Gene table of HACE1 : HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with HACE1	OMIM link	Number of associated genes	genes
616756	SPASTIC PARAPLEGIA AND PSYCHOMOTOR RETARDATION WITH OR WITHOUT SEIZURES	ClinVar, OMIM	link to OMIM	1	HACE1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ubiquitin-like protein transferase activity	GO:0019787	3.69
Rho GTPase binding	GO:0017048	5.36
enzyme binding	GO:0019899	2.27
catalytic activity	GO:0003824	1.05
Rac GTPase binding	GO:0048365	6.05
Rab GTPase binding	GO:0017137	4.96
GTPase binding	GO:0051020	4.05
Ras GTPase binding	GO:0017016	4.2
small GTPase binding	GO:0031267	4.13
transferase activity	GO:0016740	1.95
ubiquitin-protein transferase activity	GO:0004842	3.73
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
ligase activity	GO:0016874	3.72