Disease ID | Disease name | Source of annotation with HSD11B1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS604931 | CORTISONE REDUCTASE DEFICIENCY | ClinVar, OMIM | link to OMIM | 2 | H6PD, HSD11B1 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Metabolism of xenobiotics by cytochrome P450 | hsa00980 | 6.48 |
Metabolic pathways | hsa01100 | 2.49 |
Steroid hormone biosynthesis | hsa00140 | 6.93 |
Chemical carcinogenesis | hsa05204 | 6.36 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
Glucocorticoid biosynthesis | R-HSA-194002 | 9.81 |
Metabolism | R-HSA-1430728 | 2.34 |
Metabolism of steroid hormones and vitamin D | R-HSA-196071 | 7.89 |
GO term | GO ID | GO IC |
---|---|---|
steroid dehydrogenase activity | GO:0016229 | 6.34 |
oxidoreductase activity, acting on CH-OH group of donors | GO:0016614 | 4.83 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | GO:0016616 | 5.0 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | GO:0033764 | 6.48 |
catalytic activity | GO:0003824 | 1.05 |
11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity | GO:0003845 | 9.05 |
11-beta-hydroxysteroid dehydrogenase (NADP+) activity | GO:0070524 | 9.74 |
oxidoreductase activity | GO:0016491 | 3.12 |