| Disease ID | Disease name | Source of annotation with INPPL1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 258480 | OPSISMODYSPLASIA | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | INPPL1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Inositol phosphate metabolism | hsa00562 | 6.72 |
| B cell receptor signaling pathway | hsa04662 | 6.52 |
| Insulin signaling pathway | hsa04910 | 5.55 |
| Fc gamma R-mediated phagocytosis | hsa04666 | 6.21 |
| Phosphatidylinositol signaling system | hsa04070 | 6.38 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Inositol phosphate metabolism | R-HSA-1483249 | 7.52 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 7.94 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 8.34 |
| Signaling by Interleukins | R-HSA-449147 | 4.71 |
| Immune System | R-HSA-168256 | 2.37 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 5.09 |
| Interleukin-2 signaling | R-HSA-451927 | 5.05 |
| Phospholipid metabolism | R-HSA-1483257 | 5.83 |
| PI Metabolism | R-HSA-1483255 | 7.31 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Interleukin-3, 5 and GM-CSF signaling | R-HSA-512988 | 4.99 |
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| GO term | GO ID | GO IC |
|---|---|---|
| phosphoric ester hydrolase activity | GO:0042578 | 3.82 |
| SH2 domain binding | GO:0042169 | 6.34 |
| phosphatase activity | GO:0016791 | 4.11 |
| inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity | GO:0052659 | 7.54 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| phosphatidylinositol phosphate 5-phosphatase activity | GO:0034595 | 7.17 |
| inositol tetrakisphosphate phosphatase activity | GO:0052743 | 7.34 |
| hydrolase activity | GO:0016787 | 1.9 |
| SH3 domain binding | GO:0017124 | 4.98 |
| hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
| inositol phosphate phosphatase activity | GO:0052745 | 6.74 |
| actin binding | GO:0003779 | 3.74 |
| catalytic activity | GO:0003824 | 1.05 |
| phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | GO:0034485 | 8.35 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| phosphatidylinositol trisphosphate phosphatase activity | GO:0034594 | 7.79 |
| phosphatidylinositol phosphate phosphatase activity | GO:0052866 | 6.34 |
| protein domain specific binding | GO:0019904 | 3.32 |