Gene table of ISCA2 : iron-sulfur cluster assembly 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ISCA2	OMIM link	Number of associated genes	genes
PS605711	MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	4	IBA57, ISCA2, NFU1, BOLA3

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cation binding	GO:0043169	1.4
metal ion binding	GO:0046872	1.41
4 iron, 4 sulfur cluster binding	GO:0051539	6.0
transition metal ion binding	GO:0046914	2.48
iron-sulfur cluster binding	GO:0051536	5.55
2 iron, 2 sulfur cluster binding	GO:0051537	6.56
ion binding	GO:0043167	1.36
ferrous iron binding	GO:0008198	6.65
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
iron ion binding	GO:0005506	4.65
structural molecule activity	GO:0005198	3.1
metal cluster binding	GO:0051540	5.55