| Disease ID | Disease name | Source of annotation with ITGA6 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 226730 | EPIDERMOLYSIS BULLOSA JUNCTIONALIS WITH PYLORIC ATRESIA | OMIM | link to OMIM | 2 | ITGB4, ITGA6 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Focal adhesion | hsa04510 | 4.92 |
| Pathways in cancer | hsa05200 | 3.98 |
| Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
| ECM-receptor interaction | hsa04512 | 6.09 |
| Small cell lung cancer | hsa05222 | 6.17 |
| Hematopoietic cell lineage | hsa04640 | 6.18 |
| Toxoplasmosis | hsa05145 | 5.71 |
| Hypertrophic cardiomyopathy (HCM) | hsa05410 | 6.21 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | hsa05412 | 6.32 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| Dilated cardiomyopathy | hsa05414 | 6.08 |
| Regulation of actin cytoskeleton | hsa04810 | 4.9 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Integrin cell surface interactions | R-HSA-216083 | 6.57 |
| Laminin interactions | R-HSA-3000157 | 8.08 |
| Cell junction organization | R-HSA-446728 | 6.51 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 6.32 |
| Cell-Cell communication | R-HSA-1500931 | 5.87 |
| Extracellular matrix organization | R-HSA-1474244 | 4.91 |
| Collagen formation | R-HSA-1474290 | 6.56 |
| Basigin interactions | R-HSA-210991 | 8.34 |
| Syndecan interactions | R-HSA-3000170 | 8.23 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 7.1 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 7.2 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Type I hemidesmosome assembly | R-HSA-446107 | 9.52 |
| GO term | GO ID | GO IC |
|---|---|---|
| cation binding | GO:0043169 | 1.4 |
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| insulin-like growth factor I binding | GO:0031994 | 7.25 |
| integrin binding | GO:0005178 | 5.07 |
| growth factor binding | GO:0019838 | 4.89 |
| ion binding | GO:0043167 | 1.36 |
| neuregulin binding | GO:0038132 | 8.13 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein complex binding | GO:0032403 | 3.09 |
| insulin-like growth factor binding | GO:0005520 | 6.37 |
| metal ion binding | GO:0046872 | 1.41 |
| receptor binding | GO:0005102 | 2.43 |