Gene table of KCNJ6 : potassium voltage-gated channel subfamily J member 6

Gene-disease associations table

Disease ID	Disease name	Source of annotation with KCNJ6	OMIM link	Number of associated genes	genes
614098	KEPPEN-LUBINSKY SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	KCNJ6

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Estrogen signaling pathway	hsa04915	6.11
Morphine addiction	hsa05032	6.15
Retrograde endocannabinoid signaling	hsa04723	6.03
Cholinergic synapse	hsa04725	5.88
GABAergic synapse	hsa04727	6.24
Serotonergic synapse	hsa04726	5.84
Dopaminergic synapse	hsa04728	5.69
Circadian entrainment	hsa04713	6.11
Oxytocin signaling pathway	hsa04921	5.4

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Inwardly rectifying K+ channels	R-HSA-1296065	8.03
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	R-HSA-997272	8.34
Activation of G protein gated Potassium channels	R-HSA-1296041	8.34
Potassium Channels	R-HSA-1296071	6.35
GABA receptor activation	R-HSA-977443	7.2
Activation of GABAB receptors	R-HSA-991365	7.7
G protein gated Potassium channels	R-HSA-1296059	8.34
GABA B receptor activation	R-HSA-977444	7.7
Neuronal System	R-HSA-112316	4.82
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	R-HSA-112314	5.85
Transmission across Chemical Synapses	R-HSA-112315	5.28

Associated GO terms for Molecular function

GO term	GO ID	GO IC
potassium channel activity	GO:0005267	4.94
cation channel activity	GO:0005261	4.04
G-protein activated inward rectifier potassium channel activity	GO:0015467	7.44
molecular transducer activity	GO:0060089	2.32
binding	GO:0005488	0.18
substrate-specific channel activity	GO:0022838	3.67
ligand-gated ion channel activity	GO:0015276	4.8
transmembrane transporter activity	GO:0022857	2.82
voltage-gated cation channel activity	GO:0022843	4.83
passive transmembrane transporter activity	GO:0022803	3.6
metal ion transmembrane transporter activity	GO:0046873	3.71
voltage-gated potassium channel activity	GO:0005249	5.24
transporter activity	GO:0005215	2.57
ion channel activity	GO:0005216	3.71
cation transmembrane transporter activity	GO:0008324	3.32
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
ion transmembrane transporter activity	GO:0015075	3.04
voltage-gated channel activity	GO:0022832	4.49
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
channel activity	GO:0015267	3.6
gated channel activity	GO:0022836	3.96
protein binding	GO:0005515	0.46
ligand-gated channel activity	GO:0022834	4.8
voltage-gated ion channel activity	GO:0005244	4.49
potassium ion transmembrane transporter activity	GO:0015079	4.77
inward rectifier potassium channel activity	GO:0005242	6.65
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32