Gene table of KDM6A : lysine demethylase 6A

Gene-disease associations table

Disease IDDisease nameSource of annotation with KDM6AOMIM linkNumber of associated genesgenes
PS147920KABUKI SYNDROMEClinVar, OMIM link to OMIM 2KMT2D, KDM6A

Download the gene annotation in CSV format

Annotation of the gene KDM6A

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Transcriptional misregulation in cancerhsa052025.21
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Chromatin organizationR-HSA-48397265.19
HDMs demethylate histonesR-HSA-32148428.4
Chromatin modifying enzymesR-HSA-32475095.19
Associated GO terms for Molecular function
GO termGO IDGO IC
RNA polymerase II regulatory region DNA bindingGO:00010123.36
core promoter proximal region DNA bindingGO:00011593.82
chromatin DNA bindingGO:00314905.37
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
oxidoreductase activityGO:00164913.12
sequence-specific DNA bindingGO:00435652.79
structure-specific DNA bindingGO:00435664.98
sequence-specific double-stranded DNA bindingGO:19908373.2
ion bindingGO:00431671.36
core promoter proximal region sequence-specific DNA bindingGO:00009873.83
double-stranded DNA bindingGO:00036903.09
metal ion bindingGO:00468721.41
histone demethylase activity (H3-K27 specific)GO:00715588.13
identical protein bindingGO:00428022.63
cation bindingGO:00431691.4
regulatory region nucleic acid bindingGO:00010673.03
catalytic activityGO:00038241.05
transcription regulatory region DNA bindingGO:00442123.03
dioxygenase activityGO:00512135.25
organic cyclic compound bindingGO:00971591.05
demethylase activityGO:00324516.21
histone demethylase activityGO:00324526.48
transcription regulatory region sequence-specific DNA bindingGO:00009763.24
RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009773.37
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:00009783.88
chromatin bindingGO:00036823.64