| Disease ID | Disease name | Source of annotation with LCAT | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 245900 | LECITHIN:CHOLESTEROL ACYLTRANSFERASE DEFICIENCY | OMIM, HUMSAVAR | link to OMIM | 1 | LCAT |
| 136120 | FISH-EYE DISEASE | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | LCAT |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Glycerophospholipid metabolism | hsa00564 | 6.15 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| Lipoprotein metabolism | R-HSA-174824 | 8.23 |
| Lipid digestion, mobilization, and transport | R-HSA-73923 | 7.2 |
| Metabolism | R-HSA-1430728 | 2.34 |
| HDL-mediated lipid transport | R-HSA-194223 | 9.08 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| carboxylic ester hydrolase activity | GO:0052689 | 4.81 |
| hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
| catalytic activity | GO:0003824 | 1.05 |
| transferase activity | GO:0016740 | 1.95 |
| transferase activity, transferring acyl groups | GO:0016746 | 4.2 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| O-acyltransferase activity | GO:0008374 | 5.85 |
| phospholipase A2 activity | GO:0004623 | 6.24 |
| phospholipase activity | GO:0004620 | 5.16 |
| phosphatidylcholine-sterol O-acyltransferase activity | GO:0004607 | 9.74 |
| lipase activity | GO:0016298 | 4.96 |
| apolipoprotein binding | GO:0034185 | 6.97 |
| apolipoprotein A-I binding | GO:0034186 | 8.64 |
| transferase activity, transferring acyl groups other than amino-acyl groups | GO:0016747 | 4.37 |