Gene table of MECOM : MDS1 and EVI1 complex locus

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MECOM	OMIM link	Number of associated genes	genes
PS605432	RADIOULNAR SYNOSTOSIS WITH AMEGAKARYOCYTIC THROMBOCYTOPENIA	ClinVar, OMIM	link to OMIM	2	HOXA11, MECOM

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Chromatin organization	R-HSA-4839726	5.19
PKMTs methylate histone lysines	R-HSA-3214841	7.66
Chromatin modifying enzymes	R-HSA-3247509	5.19

Associated GO terms for Molecular function

GO term	GO ID	GO IC
histone-lysine N-methyltransferase activity	GO:0018024	5.93
histone methyltransferase activity	GO:0042054	5.68
lysine N-methyltransferase activity	GO:0016278	5.7
protein-lysine N-methyltransferase activity	GO:0016279	5.71
protein methyltransferase activity	GO:0008276	5.33
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
methyltransferase activity	GO:0008168	4.35
heterocyclic compound binding	GO:1901363	1.06
cation binding	GO:0043169	1.4
ion binding	GO:0043167	1.36
transferase activity	GO:0016740	1.95
transferase activity, transferring one-carbon groups	GO:0016741	4.3
metal ion binding	GO:0046872	1.41
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
S-adenosylmethionine-dependent methyltransferase activity	GO:0008757	4.81
catalytic activity	GO:0003824	1.05
N-methyltransferase activity	GO:0008170	5.26
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
protein binding	GO:0005515	0.46
protein dimerization activity	GO:0046983	2.72
nucleic acid binding transcription factor activity	GO:0001071	2.65