Gene table of MED17 : mediator complex subunit 17

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MED17	OMIM link	Number of associated genes	genes
613668	MICROCEPHALY, POSTNATAL PROGRESSIVE, WITH SEIZURES AND BRAIN ATROPHY	OMIM, HUMSAVAR	link to OMIM	1	MED17

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Thyroid hormone signaling pathway	hsa04919	5.82

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
PPARA activates gene expression	R-HSA-1989781	6.18
Generic Transcription Pathway	R-HSA-212436	3.86
Gene Expression	R-HSA-74160	2.72
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	R-HSA-400206	6.14
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	6.7
Metabolism	R-HSA-1430728	2.34
Fatty acid, triacylglycerol, and ketone body metabolism	R-HSA-535734	5.44
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Developmental Biology	R-HSA-1266738	3.48

Associated GO terms for Molecular function

GO term	GO ID	GO IC
molecular transducer activity	GO:0060089	2.32
transcription factor activity, RNA polymerase II transcription factor binding	GO:0001076	4.84
binding	GO:0005488	0.18
ubiquitin-like protein transferase activity	GO:0019787	3.69
ubiquitin-protein transferase activity	GO:0004842	3.73
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
transferase activity	GO:0016740	1.95
vitamin D receptor binding	GO:0042809	6.91
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
transcription factor binding	GO:0008134	3.46
nuclear hormone receptor binding	GO:0035257	4.7
ligand-dependent nuclear receptor transcription coactivator activity	GO:0030374	5.77
RNA polymerase II transcription cofactor activity	GO:0001104	5.22
thyroid hormone receptor binding	GO:0046966	6.34
hormone receptor binding	GO:0051427	4.57
ubiquitin protein ligase activity	GO:0061630	4.47
ubiquitin-like protein ligase activity	GO:0061659	4.44
catalytic activity	GO:0003824	1.05
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43
receptor activity	GO:0004872	2.32