Gene table of MMP19 : matrix metallopeptidase 19

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MMP19	OMIM link	Number of associated genes	genes
611543	CAVITARY OPTIC DISC ANOMALIES	ClinVar, OMIM	link to OMIM	1	MMP19

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Extracellular matrix organization	R-HSA-1474244	4.91
Degradation of the extracellular matrix	R-HSA-1474228	6.11
Collagen degradation	R-HSA-1442490	7.03

Associated GO terms for Molecular function

GO term	GO ID	GO IC
hydrolase activity	GO:0016787	1.9
endopeptidase activity	GO:0004175	3.63
metalloendopeptidase activity	GO:0004222	5.02
calcium ion binding	GO:0005509	3.17
transition metal ion binding	GO:0046914	2.48
serine hydrolase activity	GO:0017171	4.26
metal ion binding	GO:0046872	1.41
cation binding	GO:0043169	1.4
ion binding	GO:0043167	1.36
catalytic activity	GO:0003824	1.05
peptidase activity, acting on L-amino acid peptides	GO:0070011	3.26
zinc ion binding	GO:0008270	2.66
serine-type endopeptidase activity	GO:0004252	4.4
peptidase activity	GO:0008233	3.23
serine-type peptidase activity	GO:0008236	4.27
metallopeptidase activity	GO:0008237	4.5
binding	GO:0005488	0.18