Gene table of MYD88 : myeloid differentiation primary response 88

Gene-disease associations table

Disease IDDisease nameSource of annotation with MYD88OMIM linkNumber of associated genesgenes
612260MYD88 DEFICIENCYClinVar, OMIM, HUMSAVAR link to OMIM 1MYD88
153600MACROGLOBULINEMIA, WALDENSTROM, SUSCEPTIBILITY TO, 1OMIM link to OMIM 1MYD88

Download the gene annotation in CSV format

Annotation of the gene MYD88

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Pertussishsa051336.46
Salmonella infectionhsa051326.29
Legionellosishsa051346.88
Tuberculosishsa051525.17
Toll-like receptor signaling pathwayhsa046206.0
Chagas disease (American trypanosomiasis)hsa051425.99
African trypanosomiasishsa051437.68
Leishmaniasishsa051406.32
Herpes simplex infectionhsa051685.08
Malariahsa051447.15
Toxoplasmosishsa051455.71
Influenza Ahsa051645.21
Apoptosishsa042106.23
NF-kappa B signaling pathwayhsa040646.21
Hepatitis Bhsa051615.52
Measleshsa051625.6
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
MyD88 deficiency (TLR5)R-HSA-560268011.4
TRIF-mediated TLR3/TLR4 signaling R-HSA-9370616.47
Signaling by InterleukinsR-HSA-4491474.71
Toll Like Receptor 2 (TLR2) CascadeR-HSA-1814386.51
Immune SystemR-HSA-1682562.37
Toll Like Receptor 5 (TLR5) CascadeR-HSA-1681766.73
Cytokine Signaling in Immune systemR-HSA-12802153.74
Diseases associated with the TLR signaling cascadeR-HSA-56023588.34
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathwaysR-HSA-1689286.7
p75 NTR receptor-mediated signallingR-HSA-1937046.59
IRAK4 deficiency (TLR2/4)R-HSA-56030419.52
DiseaseR-HSA-16436853.33
Toll Like Receptor 10 (TLR10) CascadeR-HSA-1681426.73
Signalling by NGFR-HSA-1665204.23
Toll Like Receptor 3 (TLR3) CascadeR-HSA-1681646.47
Toll-Like Receptors CascadesR-HSA-1688985.91
p75NTR recruits signalling complexesR-HSA-2095439.28
MyD88-independent TLR3/TLR4 cascade R-HSA-1661666.47
ZBP1(DAI) mediated induction of type I IFNsR-HSA-16063228.28
Interleukin-1 signalingR-HSA-4466527.52
TRAF6 mediated NF-kB activationR-HSA-9335428.4
Toll Like Receptor TLR6:TLR2 CascadeR-HSA-1681886.56
TRAF6 mediated IRF7 activationR-HSA-9335417.98
Toll Like Receptor 4 (TLR4) CascadeR-HSA-1660166.11
Toll Like Receptor 7/8 (TLR7/8) CascadeR-HSA-1681816.68
Innate Immune SystemR-HSA-1682493.17
p75NTR signals via NF-kBR-HSA-1936398.98
TAK1 activates NFkB by phosphorylation and activation of IKKs complexR-HSA-4459898.08
RIP-mediated NFkB activation via ZBP1R-HSA-18104768.59
Cytosolic sensors of pathogen-associated DNA R-HSA-18349496.94
Diseases of Immune SystemR-HSA-52602718.34
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-31349639.28
IRAK4 deficiency (TLR5)R-HSA-560303710.98
Toll Like Receptor TLR1:TLR2 CascadeR-HSA-1681796.51
MyD88 deficiency (TLR2/4)R-HSA-56024989.52
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signalingR-HSA-9751109.08
MyD88 cascade initiated on plasma membraneR-HSA-9758716.73
MyD88 dependent cascade initiated on endosomeR-HSA-9751556.68
MyD88:Mal cascade initiated on plasma membraneR-HSA-1660586.56
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activationR-HSA-9751386.72
Activated TLR4 signallingR-HSA-1660546.27
Signal TransductionR-HSA-1625821.78
Toll Like Receptor 9 (TLR9) CascadeR-HSA-1681386.62
Associated GO terms for Molecular function
GO termGO IDGO IC
cytokine receptor bindingGO:00051264.14
tumor necrosis factor receptor superfamily bindingGO:00328135.89
death receptor bindingGO:00051236.91
Toll bindingGO:00051219.74
TIR domain bindingGO:00709769.74
protein domain specific bindingGO:00199043.32
bindingGO:00054880.18
protein bindingGO:00055150.46
growth factor receptor bindingGO:00708514.87
receptor bindingGO:00051022.43
identical protein bindingGO:00428022.63
interleukin-1 receptor bindingGO:00051496.85