| Disease ID | Disease name | Source of annotation with PLG | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 217090 | PLASMINOGEN DEFICIENCY, TYPE I | OMIM, HUMSAVAR | link to OMIM | 1 | PLG |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Influenza A | hsa05164 | 5.21 |
| Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
| Complement and coagulation cascades | hsa04610 | 6.58 |
| Staphylococcus aureus infection | hsa05150 | 6.64 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 8.59 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 9.28 |
| Platelet degranulation | R-HSA-114608 | 6.68 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 6.11 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.59 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 8.03 |
| Extracellular matrix organization | R-HSA-1474244 | 4.91 |
| Signaling by PDGF | R-HSA-186797 | 4.53 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| endopeptidase activity | GO:0004175 | 3.63 |
| serine-type endopeptidase activity | GO:0004252 | 4.4 |
| serine hydrolase activity | GO:0017171 | 4.26 |
| receptor binding | GO:0005102 | 2.43 |
| catalytic activity | GO:0003824 | 1.05 |
| peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| peptidase activity | GO:0008233 | 3.23 |
| apolipoprotein binding | GO:0034185 | 6.97 |
| protein domain specific binding | GO:0019904 | 3.32 |
| serine-type peptidase activity | GO:0008236 | 4.27 |