Gene table of PRLR : prolactin receptor

Gene-disease associations table

Disease IDDisease nameSource of annotation with PRLROMIM linkNumber of associated genesgenes
615554MULTIPLE FIBROADENOMAS OF THE BREASTClinVar, OMIM, HUMSAVAR link to OMIM 1PRLR
615555HYPERPROLACTINEMIAClinVar, OMIM, HUMSAVAR link to OMIM 1PRLR

Download the gene annotation in CSV format

Annotation of the gene PRLR

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Jak-STAT signaling pathwayhsa046305.44
Neuroactive ligand-receptor interactionhsa040804.58
Prolactin signaling pathwayhsa049176.6
Cytokine-cytokine receptor interactionhsa040604.67
PI3K-Akt signaling pathwayhsa041514.21
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Growth hormone receptor signalingR-HSA-9827728.4
Immune SystemR-HSA-1682562.37
Prolactin receptor signalingR-HSA-11705469.08
Cytokine Signaling in Immune systemR-HSA-12802153.74
Signal TransductionR-HSA-1625821.78
Signaling by ERBB4R-HSA-12363944.7
Nuclear signaling by ERBB4R-HSA-12519857.7
Associated GO terms for Molecular function
GO termGO IDGO IC
peptide hormone bindingGO:00170466.13
signaling receptor activityGO:00380232.49
molecular transducer activityGO:00600892.32
bindingGO:00054880.18
signal transducer activityGO:00048712.28
molecular function regulatorGO:00987722.51
cation bindingGO:00431691.4
peptide bindingGO:00422774.22
ion bindingGO:00431671.36
receptor activityGO:00048722.32
metal ion bindingGO:00468721.41
identical protein bindingGO:00428022.63
protein homodimerization activityGO:00428033.16
amide bindingGO:00332184.14
enzyme regulator activityGO:00302342.85
hormone bindingGO:00425625.53
prolactin receptor activityGO:00049259.74
transmembrane signaling receptor activityGO:00048882.57
ornithine decarboxylase activator activityGO:00429788.64
ornithine decarboxylase regulator activityGO:00429797.79
protein bindingGO:00055150.46
protein dimerization activityGO:00469832.72
cytokine receptor activityGO:00048965.24
transmembrane receptor activityGO:00996002.53
enzyme activator activityGO:00080473.56