| Disease ID | Disease name | Source of annotation with RAC2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 608203 | NEUTROPHIL IMMUNODEFICIENCY SYNDROME | OMIM, HUMSAVAR | link to OMIM | 1 | RAC2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| B cell receptor signaling pathway | hsa04662 | 6.52 |
| Ras signaling pathway | hsa04014 | 4.9 |
| Focal adhesion | hsa04510 | 4.92 |
| VEGF signaling pathway | hsa04370 | 6.77 |
| Pancreatic cancer | hsa05212 | 6.56 |
| Chemokine signaling pathway | hsa04062 | 5.19 |
| Colorectal cancer | hsa05210 | 6.52 |
| MAPK signaling pathway | hsa04010 | 4.63 |
| Pathways in cancer | hsa05200 | 3.98 |
| cAMP signaling pathway | hsa04024 | 5.05 |
| Rap1 signaling pathway | hsa04015 | 4.97 |
| Leukocyte transendothelial migration | hsa04670 | 5.74 |
| Fc epsilon RI signaling pathway | hsa04664 | 6.6 |
| Choline metabolism in cancer | hsa05231 | 6.09 |
| Fc gamma R-mediated phagocytosis | hsa04666 | 6.21 |
| Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
| Axon guidance | hsa04360 | 5.63 |
| Adherens junction | hsa04520 | 6.26 |
| Wnt signaling pathway | hsa04310 | 5.49 |
| Viral myocarditis | hsa05416 | 6.45 |
| Regulation of actin cytoskeleton | hsa04810 | 4.9 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| RHO GTPases Activate NADPH Oxidases | R-HSA-5668599 | 9.52 |
| RHO GTPase Effectors | R-HSA-195258 | 4.94 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 8.4 |
| beta-catenin independent WNT signaling | R-HSA-3858494 | 5.83 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 8.23 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| G alpha (12/13) signalling events | R-HSA-416482 | 6.75 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| PCP/CE pathway | R-HSA-4086400 | 6.47 |
| GPVI-mediated activation cascade | R-HSA-114604 | 7.18 |
| Signaling by Wnt | R-HSA-195721 | 4.79 |
| Rho GTPase cycle | R-HSA-194840 | 6.04 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Semaphorin interactions | R-HSA-373755 | 6.92 |
| Axon guidance | R-HSA-422475 | 3.93 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Developmental Biology | R-HSA-1266738 | 3.48 |
| GO term | GO ID | GO IC |
|---|---|---|
| kinase regulator activity | GO:0019207 | 4.5 |
| purine ribonucleoside triphosphate binding | GO:0035639 | 2.22 |
| binding | GO:0005488 | 0.18 |
| molecular function regulator | GO:0098772 | 2.51 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| purine nucleoside binding | GO:0001883 | 2.22 |
| nucleoside binding | GO:0001882 | 2.21 |
| pyrophosphatase activity | GO:0016462 | 3.04 |
| nucleotide binding | GO:0000166 | 1.96 |
| guanyl ribonucleotide binding | GO:0032561 | 3.73 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |
| ribonucleoside binding | GO:0032549 | 2.22 |
| purine nucleotide binding | GO:0017076 | 2.19 |
| GTP binding | GO:0005525 | 3.78 |
| hydrolase activity | GO:0016787 | 1.9 |
| protein kinase regulator activity | GO:0019887 | 4.6 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| GTPase activity | GO:0003924 | 4.31 |
| nucleoside-triphosphatase activity | GO:0017111 | 3.09 |
| small molecule binding | GO:0036094 | 1.89 |
| catalytic activity | GO:0003824 | 1.05 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | GO:0016818 | 3.03 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| hydrolase activity, acting on acid anhydrides | GO:0016817 | 3.03 |
| guanyl nucleotide binding | GO:0019001 | 3.73 |
| purine ribonucleotide binding | GO:0032555 | 2.2 |
| purine ribonucleoside binding | GO:0032550 | 2.22 |
| ribonucleotide binding | GO:0032553 | 2.19 |