Gene table of RNASEL : ribonuclease L

Gene-disease associations table

Disease ID	Disease name	Source of annotation with RNASEL	OMIM link	Number of associated genes	genes
601518	PROSTATE CANCER, HEREDITARY, 1	ClinVar, OMIM	link to OMIM	1	RNASEL

Download the gene annotation in CSV format

Annotation of the gene RNASEL

Associated genes in ENSEMBL

ENSG00000135828

Associated proteins - SwissProt Accession ID

Q05823

Associated PDB IDs

Cytogenetic Band

1q25.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

BRCA1

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Influenza A	hsa05164	5.21
Herpes simplex infection	hsa05168	5.08
Hepatitis C	hsa05160	5.68

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
ABC-family proteins mediated transport	R-HSA-382556	7.59
Immune System	R-HSA-168256	2.37
Transmembrane transport of small molecules	R-HSA-382551	3.79
Cytokine Signaling in Immune system	R-HSA-1280215	3.74
Interferon alpha/beta signaling	R-HSA-909733	6.04
Interferon Signaling	R-HSA-913531	4.95

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
ion binding	GO:0043167	1.36
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
cation binding	GO:0043169	1.4
ribonuclease activity	GO:0004540	5.04
endoribonuclease activity	GO:0004521	5.58
nucleotide binding	GO:0000166	1.96
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
protein kinase activity	GO:0004672	3.27
ribonucleoprotein complex binding	GO:0043021	5.15
purine nucleotide binding	GO:0017076	2.19
metal ion binding	GO:0046872	1.41
ATP binding	GO:0005524	2.43
hydrolase activity	GO:0016787	1.9
kinase activity	GO:0016301	2.93
ribonucleoside binding	GO:0032549	2.22
hydrolase activity, acting on ester bonds	GO:0016788	3.1
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
adenyl nucleotide binding	GO:0030554	2.4
nuclease activity	GO:0004518	4.33
endonuclease activity	GO:0004519	4.78
rRNA binding	GO:0019843	5.68
carbohydrate derivative binding	GO:0097367	2.03
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
adenyl ribonucleotide binding	GO:0032559	2.41
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46
organic cyclic compound binding	GO:0097159	1.05
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19