Gene table of SCARB1 : scavenger receptor class B member 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SCARB1	OMIM link	Number of associated genes	genes
610762	HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 6	ClinVar, OMIM	link to OMIM	1	SCARB1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Fat digestion and absorption	hsa04975	7.45
Bile secretion	hsa04976	6.56
Vitamin digestion and absorption	hsa04977	8.24
Ovarian steroidogenesis	hsa04913	7.07
Phagosome	hsa04145	5.27
Hepatitis C	hsa05160	5.68

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Lipoprotein metabolism	R-HSA-174824	8.23
HDL-mediated lipid transport	R-HSA-194223	9.08
Scavenging by Class B Receptors	R-HSA-3000471	10.66
Lipid digestion, mobilization, and transport	R-HSA-73923	7.2
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Metabolism	R-HSA-1430728	2.34
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	5.38
Vesicle-mediated transport	R-HSA-5653656	4.33

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cargo receptor activity	GO:0038024	5.53
signaling receptor activity	GO:0038023	2.49
lipoprotein particle receptor activity	GO:0030228	6.97
molecular transducer activity	GO:0060089	2.32
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
lipopolysaccharide binding	GO:0001530	6.69
phospholipid binding	GO:0005543	3.91
1-phosphatidylinositol binding	GO:0005545	6.74
apolipoprotein binding	GO:0034185	6.97
low-density lipoprotein particle binding	GO:0030169	7.03
phosphatidylserine binding	GO:0001786	6.24
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
high-density lipoprotein particle binding	GO:0008035	7.66
signaling pattern recognition receptor activity	GO:0008329	6.91
transporter activity	GO:0005215	2.57
lipid binding	GO:0008289	3.26
protein dimerization activity	GO:0046983	2.72
apolipoprotein A-I binding	GO:0034186	8.64
protein-lipid complex binding	GO:0071814	6.56
lipoprotein particle binding	GO:0071813	6.56
modified amino acid binding	GO:0072341	5.56
phosphatidylinositol binding	GO:0035091	4.47
virus receptor activity	GO:0001618	5.49
pattern recognition receptor activity	GO:0038187	6.91
carbohydrate derivative binding	GO:0097367	2.03
protein binding	GO:0005515	0.46
lipopolysaccharide receptor activity	GO:0001875	8.13
high-density lipoprotein particle receptor activity	GO:0070506	9.05
receptor activity	GO:0004872	2.32