Gene table of SLC6A2 : solute carrier family 6 member 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC6A2	OMIM link	Number of associated genes	genes
604715	ORTHOSTATIC INTOLERANCE	OMIM, HUMSAVAR	link to OMIM	1	SLC6A2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Na+/Cl- dependent neurotransmitter transporters	R-HSA-442660	8.73
SLC-mediated transmembrane transport	R-HSA-425407	4.95
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	R-HSA-425366	6.34
Transmembrane transport of small molecules	R-HSA-382551	3.79

Associated GO terms for Molecular function

GO term	GO ID	GO IC
neurotransmitter:sodium symporter activity	GO:0005328	6.79
dopamine transmembrane transporter activity	GO:0005329	8.13
neurotransmitter transporter activity	GO:0005326	6.52
binding	GO:0005488	0.18
cation binding	GO:0043169	1.4
sodium ion transmembrane transporter activity	GO:0015081	4.83
monoamine transmembrane transporter activity	GO:0008504	7.54
organic hydroxy compound transmembrane transporter activity	GO:1901618	6.02
ion binding	GO:0043167	1.36
transmembrane transporter activity	GO:0022857	2.82
solute:sodium symporter activity	GO:0015370	5.83
metal ion transmembrane transporter activity	GO:0046873	3.71
metal ion binding	GO:0046872	1.41
active transmembrane transporter activity	GO:0022804	3.85
norepinephrine transmembrane transporter activity	GO:0005333	9.05
solute:cation symporter activity	GO:0015294	5.15
dopamine:sodium symporter activity	GO:0005330	9.05
secondary active transmembrane transporter activity	GO:0015291	4.29
symporter activity	GO:0015293	4.78
norepinephrine:sodium symporter activity	GO:0005334	9.74
transporter activity	GO:0005215	2.57
cation transmembrane transporter activity	GO:0008324	3.32
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
ion transmembrane transporter activity	GO:0015075	3.04
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
protein binding	GO:0005515	0.46