Gene table of SPRTN : SprT-like N-terminal domain

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SPRTN	OMIM link	Number of associated genes	genes
616200	RUIJS-AALFS SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	SPRTN

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
DNA Repair	R-HSA-73894	5.8
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	7.77
Translesion Synthesis by POLH	R-HSA-110320	8.73
DNA Damage Bypass	R-HSA-73893	7.46

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cation binding	GO:0043169	1.4
nucleic acid binding	GO:0003676	1.44
organic cyclic compound binding	GO:0097159	1.05
DNA binding	GO:0003677	1.92
ubiquitin-like protein binding	GO:0032182	4.93
ion binding	GO:0043167	1.36
ubiquitin binding	GO:0043130	5.09
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
polyubiquitin binding	GO:0031593	5.98
K63-linked polyubiquitin binding	GO:0070530	6.79
metal ion binding	GO:0046872	1.41
heterocyclic compound binding	GO:1901363	1.06