Gene table of STRADA : STE20-related kinase adaptor alpha

Gene-disease associations table

Disease ID	Disease name	Source of annotation with STRADA	OMIM link	Number of associated genes	genes
611087	POLYHYDRAMNIOS, MEGALENCEPHALY, AND SYMPTOMATIC EPILEPSY	OMIM	link to OMIM	1	STRADA

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
AMPK signaling pathway	hsa04152	5.8
mTOR signaling pathway	hsa04150	6.72

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	4.85
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	8.18
IRS-mediated signalling	R-HSA-112399	4.87
PI3K Cascade	R-HSA-109704	6.68
IGF1R signaling cascade	R-HSA-2428924	4.85
PKB-mediated events	R-HSA-109703	7.66
IRS-related events triggered by IGF1R	R-HSA-2428928	4.85
mTOR signalling	R-HSA-165159	7.7
Signaling by Insulin receptor	R-HSA-74752	4.73
Signal Transduction	R-HSA-162582	1.78
Insulin receptor signalling cascade	R-HSA-74751	4.85

Associated GO terms for Molecular function

GO term	GO ID	GO IC
kinase regulator activity	GO:0019207	4.5
purine ribonucleoside triphosphate binding	GO:0035639	2.22
kinase activator activity	GO:0019209	5.58
enzyme binding	GO:0019899	2.27
enzyme activator activity	GO:0008047	3.56
molecular function regulator	GO:0098772	2.51
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
ribonucleoside binding	GO:0032549	2.22
nucleotide binding	GO:0000166	1.96
transferase activity	GO:0016740	1.95
nucleoside phosphate binding	GO:1901265	1.96
protein kinase activity	GO:0004672	3.27
purine nucleotide binding	GO:0017076	2.19
ATP binding	GO:0005524	2.43
protein kinase regulator activity	GO:0019887	4.6
enzyme regulator activity	GO:0030234	2.85
kinase activity	GO:0016301	2.93
small molecule binding	GO:0036094	1.89
kinase binding	GO:0019900	3.32
protein kinase activator activity	GO:0030295	5.68
protein serine/threonine kinase activator activity	GO:0043539	6.91
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
catalytic activity	GO:0003824	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
adenyl ribonucleotide binding	GO:0032559	2.41
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19
binding	GO:0005488	0.18