Gene table of TAB2 : TGF-beta activated kinase 1/MAP3K7 binding protein 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with TAB2OMIM linkNumber of associated genesgenes
614980CONGENITAL HEART DEFECTS, MULTIPLE TYPES, 2ClinVar, OMIM, HUMSAVAR link to OMIM 1TAB2

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Annotation of the gene TAB2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
MAPK signaling pathwayhsa040104.63
Toll-like receptor signaling pathwayhsa046206.0
NOD-like receptor signaling pathwayhsa046216.88
Leishmaniasishsa051406.32
Herpes simplex infectionhsa051685.08
Epstein-Barr virus infectionhsa051694.97
Osteoclast differentiationhsa043805.64
TNF signaling pathwayhsa046685.96
NF-kappa B signaling pathwayhsa040646.21
Toxoplasmosishsa051455.71
Measleshsa051625.6
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
TRIF-mediated TLR3/TLR4 signaling R-HSA-9370616.47
Signaling by InterleukinsR-HSA-4491474.71
IRAK2 mediated activation of TAK1 complexR-HSA-9370429.66
Toll Like Receptor 2 (TLR2) CascadeR-HSA-1814386.51
Immune SystemR-HSA-1682562.37
Toll Like Receptor TLR6:TLR2 CascadeR-HSA-1681886.56
Toll Like Receptor 5 (TLR5) CascadeR-HSA-1681766.73
Cytokine Signaling in Immune systemR-HSA-12802153.74
Innate Immune SystemR-HSA-1682493.17
Downstream TCR signalingR-HSA-2024247.01
Signaling by ERBB4R-HSA-12363944.7
Adaptive Immune SystemR-HSA-12802183.19
Toll Like Receptor 10 (TLR10) CascadeR-HSA-1681426.73
Toll Like Receptor 3 (TLR3) CascadeR-HSA-1681646.47
MyD88 dependent cascade initiated on endosomeR-HSA-9751556.68
Toll-Like Receptors CascadesR-HSA-1688985.91
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulationR-HSA-9751639.66
Toll Like Receptor 9 (TLR9) CascadeR-HSA-1681386.62
MyD88-independent TLR3/TLR4 cascade R-HSA-1661666.47
TCR signalingR-HSA-2024036.64
Interleukin-1 signalingR-HSA-4466527.52
C-type lectin receptors (CLRs)R-HSA-56214816.06
activated TAK1 mediates p38 MAPK activationR-HSA-4503028.59
TRAF6 mediated induction of TAK1 complexR-HSA-9370728.98
Fc epsilon receptor (FCERI) signalingR-HSA-24542024.03
Toll Like Receptor 4 (TLR4) CascadeR-HSA-1660166.11
Toll Like Receptor 7/8 (TLR7/8) CascadeR-HSA-1681816.68
NOD1/2 Signaling PathwayR-HSA-1686387.85
MAP kinase activation in TLR cascadeR-HSA-4502947.28
TAK1 activates NFkB by phosphorylation and activation of IKKs complexR-HSA-4459898.08
CLEC7A (Dectin-1) signalingR-HSA-56077646.38
Nuclear signaling by ERBB4R-HSA-12519857.7
Toll Like Receptor TLR1:TLR2 CascadeR-HSA-1681796.51
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activationR-HSA-9751386.72
MyD88 cascade initiated on plasma membraneR-HSA-9758716.73
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathwaysR-HSA-1686437.31
MyD88:Mal cascade initiated on plasma membraneR-HSA-1660586.56
Activated TLR4 signallingR-HSA-1660546.27
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1R-HSA-4503218.66
Signal TransductionR-HSA-1625821.78
FCERI mediated NF-kB activationR-HSA-28718375.11
Associated GO terms for Molecular function
GO termGO IDGO IC
cation bindingGO:00431691.4
transition metal ion bindingGO:00469142.48
ubiquitin-like protein bindingGO:00321824.93
ion bindingGO:00431671.36
ubiquitin bindingGO:00431305.09
bindingGO:00054880.18
protein bindingGO:00055150.46
polyubiquitin bindingGO:00315935.98
K63-linked polyubiquitin bindingGO:00705306.79
metal ion bindingGO:00468721.41
zinc ion bindingGO:00082702.66