Gene table of THRB : thyroid hormone receptor beta

Gene-disease associations table

Disease IDDisease nameSource of annotation with THRBOMIM linkNumber of associated genesgenes
274300THYROID HORMONE RESISTANCE, GENERALIZED, AUTOSOMAL RECESSIVEClinVar, OMIM link to OMIM 1THRB
188570THYROID HORMONE RESISTANCE, GENERALIZED, AUTOSOMAL DOMINANTClinVar, OMIM, HUMSAVAR link to OMIM 1THRB
145650THYROID HORMONE RESISTANCE, SELECTIVE PITUITARYClinVar, OMIM, HUMSAVAR link to OMIM 1THRB

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Annotation of the gene THRB

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Thyroid hormone signaling pathwayhsa049195.82
Neuroactive ligand-receptor interactionhsa040804.58
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Nuclear Receptor transcription pathwayR-HSA-3832807.31
Generic Transcription PathwayR-HSA-2124363.86
Gene ExpressionR-HSA-741602.72
Associated GO terms for Molecular function
GO termGO IDGO IC
signaling receptor activityGO:00380232.49
nucleic acid bindingGO:00036761.44
enzyme bindingGO:00198992.27
molecular transducer activityGO:00600892.32
transcription factor activity, direct ligand regulated sequence-specific DNA bindingGO:00985315.87
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
signal transducer activityGO:00048712.28
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingGO:00048795.87
sequence-specific DNA bindingGO:00435652.79
structure-specific DNA bindingGO:00435664.98
transition metal ion bindingGO:00469142.48
transcription corepressor activityGO:00037144.33
zinc ion bindingGO:00082702.66
transcription cofactor activityGO:00037123.44
ion bindingGO:00431671.36
transcription factor activity, transcription factor bindingGO:00009893.36
transcription factor activity, protein bindingGO:00009883.35
metal ion bindingGO:00468721.41
RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009813.29
cation bindingGO:00431691.4
thyroid hormone bindingGO:00703247.95
hormone bindingGO:00425625.53
chromatin DNA bindingGO:00314905.37
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
nucleic acid binding transcription factor activityGO:00010712.65
steroid hormone receptor activityGO:00037075.66
protein bindingGO:00055150.46
chromatin bindingGO:00036823.64
thyroid hormone receptor activityGO:00048877.66
receptor activityGO:00048722.32