Gene table of TLR5 : toll like receptor 5

Gene-disease associations table

Disease IDDisease nameSource of annotation with TLR5OMIM linkNumber of associated genesgenes
608556LEGIONNAIRE DISEASE, SUSCEPTIBILITY TOClinVar, OMIM link to OMIM 1TLR5
615557MELIOIDOSIS, SUSCEPTIBILITY TOOMIM link to OMIM 1TLR5
601744SYSTEMIC LUPUS ERYTHEMATOSUS, SUSCEPTIBILITY TO, 1OMIM link to OMIM 1TLR5

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Annotation of the gene TLR5

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Salmonella infectionhsa051326.29
Pathogenic Escherichia coli infectionhsa051306.99
Toll-like receptor signaling pathwayhsa046206.0
Inflammatory bowel disease (IBD)hsa053216.43
Legionellosishsa051346.88
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
MyD88 deficiency (TLR5)R-HSA-560268011.4
Toll Like Receptor 10 (TLR10) CascadeR-HSA-1681426.73
Innate Immune SystemR-HSA-1682493.17
Immune SystemR-HSA-1682562.37
Toll Like Receptor 5 (TLR5) CascadeR-HSA-1681766.73
MyD88 cascade initiated on plasma membraneR-HSA-9758716.73
Toll-Like Receptors CascadesR-HSA-1688985.91
Diseases associated with the TLR signaling cascadeR-HSA-56023588.34
Diseases of Immune SystemR-HSA-52602718.34
IRAK4 deficiency (TLR5)R-HSA-560303710.98
DiseaseR-HSA-16436853.33
Associated GO terms for Molecular function
GO termGO IDGO IC
cytokine receptor bindingGO:00051264.14
signaling receptor activityGO:00380232.49
interleukin-1 receptor bindingGO:00051496.85
protein bindingGO:00055150.46
growth factor receptor bindingGO:00708514.87
molecular transducer activityGO:00600892.32
transmembrane signaling receptor activityGO:00048882.57
receptor activityGO:00048722.32
signal transducer activityGO:00048712.28
receptor bindingGO:00051022.43
transmembrane receptor activityGO:00996002.53
bindingGO:00054880.18