Disease ID | Disease name | Source of annotation with TLR5 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
608556 | LEGIONNAIRE DISEASE, SUSCEPTIBILITY TO | ClinVar, OMIM | link to OMIM | 1 | TLR5 |
615557 | MELIOIDOSIS, SUSCEPTIBILITY TO | OMIM | link to OMIM | 1 | TLR5 |
601744 | SYSTEMIC LUPUS ERYTHEMATOSUS, SUSCEPTIBILITY TO, 1 | OMIM | link to OMIM | 1 | TLR5 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Salmonella infection | hsa05132 | 6.29 |
Pathogenic Escherichia coli infection | hsa05130 | 6.99 |
Toll-like receptor signaling pathway | hsa04620 | 6.0 |
Inflammatory bowel disease (IBD) | hsa05321 | 6.43 |
Legionellosis | hsa05134 | 6.88 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
MyD88 deficiency (TLR5) | R-HSA-5602680 | 11.4 |
Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 6.73 |
Innate Immune System | R-HSA-168249 | 3.17 |
Immune System | R-HSA-168256 | 2.37 |
Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 6.73 |
MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 6.73 |
Toll-Like Receptors Cascades | R-HSA-168898 | 5.91 |
Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 8.34 |
Diseases of Immune System | R-HSA-5260271 | 8.34 |
IRAK4 deficiency (TLR5) | R-HSA-5603037 | 10.98 |
Disease | R-HSA-1643685 | 3.33 |
GO term | GO ID | GO IC |
---|---|---|
cytokine receptor binding | GO:0005126 | 4.14 |
signaling receptor activity | GO:0038023 | 2.49 |
interleukin-1 receptor binding | GO:0005149 | 6.85 |
protein binding | GO:0005515 | 0.46 |
growth factor receptor binding | GO:0070851 | 4.87 |
molecular transducer activity | GO:0060089 | 2.32 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
receptor activity | GO:0004872 | 2.32 |
signal transducer activity | GO:0004871 | 2.28 |
receptor binding | GO:0005102 | 2.43 |
transmembrane receptor activity | GO:0099600 | 2.53 |
binding | GO:0005488 | 0.18 |