| Disease ID | Disease name | Source of annotation with TTR | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 145680 | HYPERTHYROXINEMIA, DYSTRANSTHYRETINEMIC | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | TTR |
| 115430 | CARPAL TUNNEL SYNDROME | OMIM, HUMSAVAR | link to OMIM | 1 | TTR |
| 105210 | AMYLOIDOSIS, HEREDITARY, TRANSTHYRETIN-RELATED | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | TTR |
Download the gene annotation in CSV format
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Retinoid metabolism and transport | R-HSA-975634 | 7.59 |
| Amyloids | R-HSA-977225 | 7.37 |
| Visual phototransduction | R-HSA-2187338 | 6.44 |
| Diseases of signal transduction | R-HSA-5663202 | 4.89 |
| Diseases associated with visual transduction | R-HSA-2474795 | 9.28 |
| Retinoid cycle disease events | R-HSA-2453864 | 9.28 |
| Extracellular matrix organization | R-HSA-1474244 | 4.91 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| The canonical retinoid cycle in rods (twilight vision) | R-HSA-2453902 | 8.52 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 7.1 |
| Disease | R-HSA-1643685 | 3.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| hormone activity | GO:0005179 | 4.95 |
| thyroid hormone binding | GO:0070324 | 7.95 |
| receptor binding | GO:0005102 | 2.43 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein dimerization activity | GO:0046983 | 2.72 |
| protein heterodimerization activity | GO:0046982 | 3.64 |
| hormone binding | GO:0042562 | 5.53 |
| identical protein binding | GO:0042802 | 2.63 |