Gene table of UBA1 : ubiquitin like modifier activating enzyme 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with UBA1	OMIM link	Number of associated genes	genes
301830	SPINAL MUSCULAR ATROPHY, X-LINKED 2	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	UBA1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Parkinson's disease	hsa05012	5.59
Ubiquitin mediated proteolysis	hsa04120	5.63

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Class I MHC mediated antigen processing & presentation	R-HSA-983169	4.65
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	5.19
Immune System	R-HSA-168256	2.37
Adaptive Immune System	R-HSA-1280218	3.19

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
ubiquitin activating enzyme activity	GO:0004839	8.13
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
ubiquitin-like protein transferase activity	GO:0019787	3.69
ubiquitin-protein transferase activity	GO:0004842	3.73
small protein activating enzyme activity	GO:0008641	7.44
nucleotide binding	GO:0000166	1.96
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
ATP binding	GO:0005524	2.43
poly(A) RNA binding	GO:0044822	2.69
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
ligase activity	GO:0016874	3.72
ligase activity, forming carbon-sulfur bonds	GO:0016877	6.05
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
adenyl ribonucleotide binding	GO:0032559	2.41
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19