Disease table of HYPERTRIGLYCERIDEMIA, FAMILIAL OMIM ID: 145750

Gene-disease associations table

GeneAssociated with HYPERTRIGLYCERIDEMIA, FAMILIAL inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
LIPIOMIM, HUMSAVARHGNC link21q11.21145750
APOA5OMIMHGNC link11q23.32144650, 145750

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
APOA5YES6PPARGC1A, SREBF1, USF2, RORA, PPARA, USF10
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
sulfur compound binding (GO:1901681) 4.322APOA5, LIPI
carbohydrate derivative binding (GO:0097367) 2.032APOA5, LIPI
glycosaminoglycan binding (GO:0005539) 4.422APOA5, LIPI
binding (GO:0005488) 0.182APOA5, LIPI
heparin binding (GO:0008201) 4.682APOA5, LIPI

NET-GE enrichment

Term New enriched termICP valueGenes
sulfur compound binding (GO:1901681) -4.320.03APOA5, LIPI
glycosaminoglycan binding (GO:0005539) -4.420.003APOA5, LIPI
heparin binding (GO:0008201) -4.680.015APOA5, LIPI
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
single-organism catabolic process (GO:0044712) 3.212APOA5, LIPI
primary metabolic process (GO:0044238) 0.692APOA5, LIPI
single-organism metabolic process (GO:0044710) 1.632APOA5, LIPI
multicellular organismal process (GO:0032501) 1.452APOA5, LIPI
lipid metabolic process (GO:0006629) 2.682APOA5, LIPI
single-multicellular organism process (GO:0044707) 1.782APOA5, LIPI
organic substance catabolic process (GO:1901575) 2.452APOA5, LIPI
lipid catabolic process (GO:0016042) 4.212APOA5, LIPI
organic substance metabolic process (GO:0071704) 0.632APOA5, LIPI
metabolic process (GO:0008152) 0.582APOA5, LIPI
catabolic process (GO:0009056) 2.382APOA5, LIPI
single-organism process (GO:0044699) 0.482APOA5, LIPI

NET-GE enrichment

Term New enriched termICP valueGenes
lipid catabolic process (GO:0016042) -4.210.021APOA5, LIPI
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
extracellular region (GO:0005576) 2.182APOA5, LIPI
extracellular region part (GO:0044421) 1.572APOA5, LIPI
extracellular space (GO:0005615) 2.632APOA5, LIPI