Disease table of EPIDERMODYSPLASIA VERRUCIFORMIS OMIM ID: 226400

Gene-disease associations table

GeneAssociated with EPIDERMODYSPLASIA VERRUCIFORMIS inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
TMC6ClinVar, OMIMHGNC link17q25.31226400
TMC8ClinVar, OMIMHGNC link17q25.31226400

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By sub-band
Shared sub_bandNumber of genes associated with the diseaseGenes associated with the disease
17q25.32TMC8, TMC6
By band
Shared bandNumber of genes associated with the diseaseGenes associated with the disease
17q252TMC8, TMC6
By region
Shared regionNumber of genes associated with the diseaseGenes associated with the disease
17q22TMC8, TMC6
By arm
Shared armNumber of genes associated with the diseaseGenes associated with the disease
17q2TMC8, TMC6
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
172TMC8, TMC6
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
Gene1Gene2Direct interactionMore information
TMC6TMC8yes, complexIn vivo TMC6 and TMC8 interact and form a complex with the zinc transporter 1 (SLC30A1).
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.182TMC6, TMC8
protein binding (GO:0005515) 0.462TMC6, TMC8
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
ion transport (GO:0006811) 2.662TMC6, TMC8
transport (GO:0006810) 1.512TMC6, TMC8
localization (GO:0051179) 1.42TMC6, TMC8
establishment of localization (GO:0051234) 1.482TMC6, TMC8
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
endoplasmic reticulum (GO:0005783) 2.562TMC6, TMC8
endoplasmic reticulum membrane (GO:0005789) 2.952TMC6, TMC8
intracellular organelle (GO:0043229) 0.512TMC6, TMC8
membrane-bounded organelle (GO:0043227) 0.472TMC6, TMC8
organelle (GO:0043226) 0.42TMC6, TMC8
intrinsic component of membrane (GO:0031224) 1.132TMC6, TMC8
cytoplasm (GO:0005737) 1.012TMC6, TMC8
extracellular exosome (GO:0070062) 1.892TMC6, TMC8
integral component of membrane (GO:0016021) 1.142TMC6, TMC8
membrane (GO:0016020) 0.682TMC6, TMC8
membrane-bounded vesicle (GO:0031988) 1.712TMC6, TMC8
endoplasmic reticulum part (GO:0044432) 2.732TMC6, TMC8
Golgi apparatus (GO:0005794) 2.72TMC6, TMC8
nuclear membrane (GO:0031965) 4.22TMC6, TMC8
vesicle (GO:0031982) 1.642TMC6, TMC8
extracellular vesicle (GO:1903561) 1.892TMC6, TMC8
organelle membrane (GO:0031090) 1.972TMC6, TMC8
extracellular organelle (GO:0043230) 1.892TMC6, TMC8
intracellular membrane-bounded organelle (GO:0043231) 0.62TMC6, TMC8
cell part (GO:0044464) 0.112TMC6, TMC8
intracellular organelle part (GO:0044446) 0.812TMC6, TMC8
cytoplasmic part (GO:0044444) 0.822TMC6, TMC8
nuclear part (GO:0044428) 1.552TMC6, TMC8
intracellular part (GO:0044424) 0.282TMC6, TMC8
membrane part (GO:0044425) 0.952TMC6, TMC8
extracellular region part (GO:0044421) 1.572TMC6, TMC8
organelle part (GO:0044422) 0.792TMC6, TMC8

NET-GE enrichment

Term New enriched termICP valueGenes
nuclear membrane (GO:0031965) -4.20.004TMC6, TMC8
endoplasmic reticulum membrane (GO:0005789) -2.950.049TMC6, TMC8