Disease table of AMYLOIDOSIS, PRIMARY LOCALIZED CUTANEOUS OMIM ID: PS105250

Gene-disease associations table

GeneAssociated with AMYLOIDOSIS, PRIMARY LOCALIZED CUTANEOUS inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
OSMRClinVar, OMIM, HUMSAVARHGNC link5p13.11PS105250
IL31RAClinVar, OMIM, HUMSAVARHGNC link5q11.21PS105250

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
52OSMR, IL31RA
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
Gene1Gene2Direct interactionMore information
IL31RAOSMRyes, complexThey associate to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. [UniProt]
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
signaling receptor activity (GO:0038023) 2.492IL31RA, OSMR
protein binding (GO:0005515) 0.462IL31RA, OSMR
molecular transducer activity (GO:0060089) 2.322IL31RA, OSMR
transmembrane signaling receptor activity (GO:0004888) 2.572IL31RA, OSMR
binding (GO:0005488) 0.182IL31RA, OSMR
signal transducer activity (GO:0004871) 2.282IL31RA, OSMR
cytokine receptor activity (GO:0004896) 5.242IL31RA, OSMR
transmembrane receptor activity (GO:0099600) 2.532IL31RA, OSMR
receptor activity (GO:0004872) 2.322IL31RA, OSMR
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
regulation of cell proliferation (GO:0042127) 2.412IL31RA, OSMR
positive regulation of cell proliferation (GO:0008284) 3.012IL31RA, OSMR
cytokine-mediated signaling pathway (GO:0019221) 3.62IL31RA, OSMR
response to stimulus (GO:0050896) 1.222IL31RA, OSMR
positive regulation of response to stimulus (GO:0048584) 2.182IL31RA, OSMR
regulation of response to stimulus (GO:0048583) 1.542IL31RA, OSMR
regulation of cellular process (GO:0050794) 0.52IL31RA, OSMR
biological regulation (GO:0065007) 0.392IL31RA, OSMR
signal transduction (GO:0007165) 1.282IL31RA, OSMR
cell surface receptor signaling pathway (GO:0007166) 2.092IL31RA, OSMR
positive regulation of biological process (GO:0048518) 1.22IL31RA, OSMR
regulation of biological process (GO:0050789) 0.452IL31RA, OSMR
positive regulation of cellular process (GO:0048522) 1.32IL31RA, OSMR
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
plasma membrane region (GO:0098590) 2.972IL31RA, OSMR
integral component of membrane (GO:0016021) 1.142IL31RA, OSMR
membrane (GO:0016020) 0.682IL31RA, OSMR
cell part (GO:0044464) 0.112IL31RA, OSMR
plasma membrane (GO:0005886) 1.392IL31RA, OSMR
membrane part (GO:0044425) 0.952IL31RA, OSMR
plasma membrane part (GO:0044459) 1.952IL31RA, OSMR
intrinsic component of membrane (GO:0031224) 1.132IL31RA, OSMR