Disease table of MYOPIA OMIM ID: PS160700

Gene-disease associations table

GeneAssociated with MYOPIA inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
LRPAP1OMIMHGNC link4p16.31PS160700
ZNF644ClinVar, OMIM, HUMSAVARHGNC link1p22.21PS160700
SCO2ClinVar, OMIM, HUMSAVARHGNC link22q13.332604377, PS160700
PRIMPOLClinVar, OMIM, HUMSAVARHGNC link4q35.11PS160700
SLC39A5ClinVar, OMIM, HUMSAVARHGNC link12q13.31PS160700

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.184SCO2, LRPAP1, ZNF644, PRIMPOL
cation binding (GO:0043169) 1.43ZNF644, SCO2, PRIMPOL
metal ion binding (GO:0046872) 1.413ZNF644, SCO2, PRIMPOL
protein binding (GO:0005515) 0.463LRPAP1, SCO2, PRIMPOL
ion binding (GO:0043167) 1.363ZNF644, SCO2, PRIMPOL
transition metal ion binding (GO:0046914) 2.482SCO2, PRIMPOL
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cellular process (GO:0009987) 0.265SLC39A5, SCO2, LRPAP1, ZNF644, PRIMPOL
biological regulation (GO:0065007) 0.394SLC39A5, SCO2, LRPAP1, ZNF644
response to stimulus (GO:0050896) 1.223SLC39A5, SCO2, PRIMPOL
transport (GO:0006810) 1.513SLC39A5, LRPAP1, SCO2
cellular metabolic process (GO:0044237) 0.693ZNF644, SCO2, PRIMPOL
regulation of cellular process (GO:0050794) 0.53SLC39A5, LRPAP1, ZNF644
metabolic process (GO:0008152) 0.583ZNF644, SCO2, PRIMPOL
localization (GO:0051179) 1.43SLC39A5, LRPAP1, SCO2
establishment of localization (GO:0051234) 1.483SLC39A5, LRPAP1, SCO2
regulation of biological process (GO:0050789) 0.453SLC39A5, LRPAP1, ZNF644
developmental process (GO:0032502) 1.362SLC39A5, SCO2
primary metabolic process (GO:0044238) 0.692ZNF644, PRIMPOL
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.432SLC39A5, ZNF644
regulation of primary metabolic process (GO:0080090) 1.082SLC39A5, ZNF644
regulation of metabolic process (GO:0019222) 1.022SLC39A5, ZNF644
anatomical structure development (GO:0048856) 1.582SLC39A5, SCO2
regulation of cellular biosynthetic process (GO:0031326) 1.382SLC39A5, ZNF644
ion homeostasis (GO:0050801) 3.422SLC39A5, SCO2
metal ion homeostasis (GO:0055065) 3.612SLC39A5, SCO2
regulation of cellular metabolic process (GO:0031323) 1.072SLC39A5, ZNF644
homeostatic process (GO:0042592) 2.612SLC39A5, SCO2
cellular biosynthetic process (GO:0044249) 1.372ZNF644, PRIMPOL
cellular nitrogen compound metabolic process (GO:0034641) 1.222ZNF644, PRIMPOL
nitrogen compound metabolic process (GO:0006807) 1.132ZNF644, PRIMPOL
cellular macromolecule biosynthetic process (GO:0034645) 1.662ZNF644, PRIMPOL
transition metal ion homeostasis (GO:0055076) 5.092SLC39A5, SCO2
inorganic ion homeostasis (GO:0098771) 3.432SLC39A5, SCO2
macromolecule metabolic process (GO:0043170) 0.832ZNF644, PRIMPOL
organic cyclic compound biosynthetic process (GO:1901362) 1.662ZNF644, PRIMPOL
organic cyclic compound metabolic process (GO:1901360) 1.262ZNF644, PRIMPOL
RNA biosynthetic process (GO:0032774) 1.842ZNF644, PRIMPOL
organic substance biosynthetic process (GO:1901576) 1.342ZNF644, PRIMPOL
cellular response to stimulus (GO:0051716) 1.972SLC39A5, PRIMPOL
cellular transition metal ion homeostasis (GO:0046916) 5.422SLC39A5, SCO2
cellular macromolecule metabolic process (GO:0044260) 0.932ZNF644, PRIMPOL
organic substance metabolic process (GO:0071704) 0.632ZNF644, PRIMPOL
transition metal ion transport (GO:0000041) 5.052SLC39A5, SCO2
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.462SLC39A5, ZNF644
cellular metal ion homeostasis (GO:0006875) 3.752SLC39A5, SCO2
animal organ development (GO:0048513) 2.532SLC39A5, SCO2
single-organism process (GO:0044699) 0.482SLC39A5, SCO2
regulation of nucleic acid-templated transcription (GO:1903506) 1.552SLC39A5, ZNF644
regulation of biological quality (GO:0065008) 1.682SLC39A5, SCO2
regulation of gene expression (GO:0010468) 1.372SLC39A5, ZNF644
heterocycle biosynthetic process (GO:0018130) 1.72ZNF644, PRIMPOL
cellular homeostasis (GO:0019725) 3.232SLC39A5, SCO2
metal ion transport (GO:0030001) 3.362SLC39A5, SCO2
nucleobase-containing compound metabolic process (GO:0006139) 1.352ZNF644, PRIMPOL
regulation of macromolecule metabolic process (GO:0060255) 1.082SLC39A5, ZNF644
cation transport (GO:0006812) 3.112SLC39A5, SCO2
ion transport (GO:0006811) 2.662SLC39A5, SCO2
regulation of biosynthetic process (GO:0009889) 1.372SLC39A5, ZNF644
cellular ion homeostasis (GO:0006873) 3.572SLC39A5, SCO2
cation homeostasis (GO:0055080) 3.462SLC39A5, SCO2
response to stress (GO:0006950) 1.82SLC39A5, PRIMPOL
macromolecule biosynthetic process (GO:0009059) 1.612ZNF644, PRIMPOL
eye development (GO:0001654) 5.072SLC39A5, SCO2
regulation of nitrogen compound metabolic process (GO:0051171) 1.362SLC39A5, ZNF644
cellular cation homeostasis (GO:0030003) 3.62SLC39A5, SCO2
regulation of RNA biosynthetic process (GO:2001141) 1.552SLC39A5, ZNF644
nucleobase-containing compound biosynthetic process (GO:0034654) 1.722ZNF644, PRIMPOL
cellular chemical homeostasis (GO:0055082) 3.42SLC39A5, SCO2
cellular aromatic compound metabolic process (GO:0006725) 1.32ZNF644, PRIMPOL
heterocycle metabolic process (GO:0046483) 1.312ZNF644, PRIMPOL
RNA metabolic process (GO:0016070) 1.592ZNF644, PRIMPOL
nucleic acid metabolic process (GO:0090304) 1.462ZNF644, PRIMPOL
cellular nitrogen compound biosynthetic process (GO:0044271) 1.592ZNF644, PRIMPOL
sensory organ development (GO:0007423) 4.822SLC39A5, SCO2
regulation of RNA metabolic process (GO:0051252) 1.522SLC39A5, ZNF644
single-organism cellular process (GO:0044763) 0.652SLC39A5, SCO2
biosynthetic process (GO:0009058) 1.322ZNF644, PRIMPOL
chemical homeostasis (GO:0048878) 2.972SLC39A5, SCO2
regulation of transcription, DNA-templated (GO:0006355) 1.562SLC39A5, ZNF644
regulation of macromolecule biosynthetic process (GO:0010556) 1.432SLC39A5, ZNF644
single-organism developmental process (GO:0044767) 1.492SLC39A5, SCO2
cellular response to stress (GO:0033554) 2.512SLC39A5, PRIMPOL
aromatic compound biosynthetic process (GO:0019438) 1.72ZNF644, PRIMPOL
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cell part (GO:0044464) 0.115SLC39A5, SCO2, LRPAP1, ZNF644, PRIMPOL
membrane-bounded organelle (GO:0043227) 0.475SLC39A5, SCO2, LRPAP1, ZNF644, PRIMPOL
organelle (GO:0043226) 0.45SLC39A5, SCO2, LRPAP1, ZNF644, PRIMPOL
intracellular part (GO:0044424) 0.284SCO2, LRPAP1, ZNF644, PRIMPOL
intracellular organelle (GO:0043229) 0.514SCO2, LRPAP1, ZNF644, PRIMPOL
intracellular membrane-bounded organelle (GO:0043231) 0.64SCO2, LRPAP1, ZNF644, PRIMPOL
organelle lumen (GO:0043233) 3.053LRPAP1, SCO2, PRIMPOL
membrane (GO:0016020) 0.683SLC39A5, LRPAP1, SCO2
membrane-enclosed lumen (GO:0031974) 3.053LRPAP1, SCO2, PRIMPOL
intracellular organelle part (GO:0044446) 0.813LRPAP1, SCO2, PRIMPOL
intracellular organelle lumen (GO:0070013) 3.053LRPAP1, SCO2, PRIMPOL
cytoplasmic part (GO:0044444) 0.823LRPAP1, SCO2, PRIMPOL
organelle part (GO:0044422) 0.793LRPAP1, SCO2, PRIMPOL
vesicle (GO:0031982) 1.642SLC39A5, LRPAP1
integral component of membrane (GO:0016021) 1.142SLC39A5, LRPAP1
mitochondrion (GO:0005739) 2.422SCO2, PRIMPOL
mitochondrial part (GO:0044429) 2.922SCO2, PRIMPOL
plasma membrane (GO:0005886) 1.392SLC39A5, LRPAP1
mitochondrial matrix (GO:0005759) 4.032SCO2, PRIMPOL
membrane part (GO:0044425) 0.952SLC39A5, LRPAP1
nucleus (GO:0005634) 1.072ZNF644, PRIMPOL
intrinsic component of membrane (GO:0031224) 1.132SLC39A5, LRPAP1