Disease table of PEROXISOME BIOGENESIS DISORDER OMIM ID: PS214100

Gene-disease associations table

GeneAssociated with PEROXISOME BIOGENESIS DISORDER inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
PEX1ClinVar, OMIM, HUMSAVARHGNC link7q21.21PS214100
PEX3ClinVar, OMIM, HUMSAVARHGNC link6q24.21PS214100
PEX2ClinVar, OMIM, HUMSAVARHGNC link8q21.131PS214100
PEX5ClinVar, OMIM, HUMSAVARHGNC link12p13.312PS214100, PS215100
PEX7ClinVar, OMIM, HUMSAVARHGNC link6q23.33PS214100, 266500, PS215100
PEX26ClinVar, OMIM, HUMSAVARHGNC link22q11.211PS214100
PEX6ClinVar, OMIM, HUMSAVARHGNC link6p21.11PS214100
PEX19OMIMHGNC link1q23.21PS214100
PEX11BClinVar, OMIMHGNC link1q21.11PS214100
PEX10ClinVar, OMIM, HUMSAVARHGNC link1p36.321PS214100
PEX13ClinVar, OMIM, HUMSAVARHGNC link2p151PS214100
PEX12ClinVar, OMIM, HUMSAVARHGNC link17q121PS214100
PEX14ClinVar, OMIMHGNC link1p36.221PS214100
PEX16ClinVar, OMIM, HUMSAVARHGNC link11p11.21PS214100

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By band
Shared bandNumber of genes associated with the diseaseGenes associated with the disease
1p362PEX10, PEX14
By region
Shared regionNumber of genes associated with the diseaseGenes associated with the disease
6q22PEX3, PEX7
1q22PEX19, PEX11B
1p32PEX10, PEX14
By arm
Shared armNumber of genes associated with the diseaseGenes associated with the disease
1q2PEX19, PEX11B
1p2PEX10, PEX14
6q2PEX3, PEX7
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
14PEX19, PEX10, PEX11B, PEX14
63PEX3, PEX7, PEX6
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
PEX1PEX26Yes1PEX6
PEX1PEX6Yes2THBS3, PEX26
PEX1PEX19No1PEX26
PEX3PEX2No1PEX14
PEX3PEX5No1PEX14
PEX3PEX7No1PEX14
PEX3PEX26No1PEX19
PEX3PEX19Yes3ABCD3, PEX14, ABCD1
PEX3PEX11BNo1PEX19
PEX3PEX10No2PEX19, PEX14
PEX3PEX13No2PEX19, PEX14
PEX3PEX12No2PEX19, PEX14
PEX3PEX14Yes3PEX19, PEX14, ABCD3
PEX3PEX16No2PEX19, PEX14
PEX2PEX5Yes2PEX14, PEX10
PEX2PEX7No2PEX14, PEX5
PEX2PEX19No2PEX14, PEX10
PEX2PEX10Yes3PEX14, PEX10, PEX5
PEX2PEX13No2PEX14, PEX5
PEX2PEX12No3PEX14, PEX10, PEX5
PEX2PEX14Yes3PEX14, PEX10, PEX5
PEX2PEX16No1PEX14
PEX5PEX7Yes3ACAA1, PEX14, PEX13
PEX5PEX19No5PEX12, PEX10, PEX13, XPO1, PEX14
PEX5PEX11BNo1FIS1
PEX5PEX10Yes5PEX12, PEX2, PEX10, PEX14, MKRN3
PEX5PEX13Yes3PEX14, PEX7, PEX13
PEX5PEX12Yes2PEX14, PEX10
PEX5PEX14Yes13SLC27A2, PEX13, PEX12, HSD17B4, GNPAT, DHRS4, PEX10, AP2M1, NEU2, AGPS, PEX14, PEX2, PEX7
PEX5PEX16No1PEX14
PEX7PEX19No2PEX14, PEX13
PEX7PEX10No2PEX14, PEX5
PEX7PEX13Yes3PEX14, PEX5, PEX13
PEX7PEX12No2PEX14, PEX5
PEX7PEX14Yes10CCT7, TCP1, PEX13, CCT5, CCT3, CCT2, PEX5, CCT4, PEX14, CCT6A
PEX7PEX16No1PEX14
PEX26PEX6Yes1PEX1
PEX26PEX19Yes1ELAVL1
PEX26PEX11BNo1PEX19
PEX26PEX10No1PEX19
PEX26PEX13No1PEX19
PEX26PEX12No1PEX19
PEX26PEX14No1PEX19
PEX26PEX16No1PEX19
PEX6PEX19No1PEX26
PEX19PEX11BYes2PEX11B, FAF2
PEX19PEX10Yes3PEX12, PEX10, PEX14
PEX19PEX13Yes2PEX14, PEX13
PEX19PEX12Yes2PEX14, PEX10
PEX19PEX14Yes7PEX16, PEX13, ABCD3, PEX12, PEX10, PEX14, PEX3
PEX19PEX16Yes1PEX14
PEX11BPEX10No1PEX19
PEX11BPEX13No1PEX19
PEX11BPEX12No1PEX19
PEX11BPEX14No1PEX19
PEX11BPEX16No1PEX19
PEX10PEX13No3PEX19, PEX14, PEX5
PEX10PEX12Yes4PEX14, PEX19, PEX10, PEX5
PEX10PEX14Yes6PEX19, PEX12, PEX5, PEX10, PEX2, PEX14
PEX10PEX16No2PEX19, PEX14
PEX13PEX12No3PEX19, PEX14, PEX5
PEX13PEX14Yes5PEX7, PEX19, PEX14, PEX5, PEX13
PEX13PEX16No2PEX19, PEX14
PEX12PEX14Yes4PEX14, PEX19, PEX10, PEX5
PEX12PEX16No2PEX19, PEX14
PEX14PEX16Yes2PEX19, PEX14

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
PEX1PEX3No-3UBC, PEX5, PEX13
PEX1PEX2No-3PEX5L, PEX5, PEX13
PEX1PEX5Yesbinding3UBC, PEX6, PEX13
PEX1PEX7No-3PEX5L, PEX5, PEX13
PEX1PEX26Yesbinding1PEX6
PEX1PEX6Yesbinding3PEX26, PEX5L, PEX5
PEX1PEX19No-5UBC, PEX26, PEX5L, PEX5, PEX13
PEX1PEX10No-3PEX5L, PEX5, PEX13
PEX1PEX13Yesbinding2PEX5L, PEX5
PEX1PEX12No-3PEX5L, PEX5, PEX13
PEX1PEX14No-4UBC, PEX5L, PEX5, PEX13
PEX3PEX2No-3PEX19, PEX5, PEX13
PEX3PEX5Yesbinding3UBC, PEX19, PEX13
PEX3PEX7No-2PEX5, PEX13
PEX3PEX26No-1PEX19
PEX3PEX6No-1PEX5
PEX3PEX19Yesbinding3UBC, PEX5, PEX13
PEX3PEX10No-3PEX19, PEX5, PEX13
PEX3PEX13Yesbinding2PEX19, PEX5
PEX3PEX12No-3PEX19, PEX5, PEX13
PEX3PEX14No-4UBC, PEX19, PEX5, PEX13
PEX3PEX16No-1PEX19
PEX2PEX5Yesbinding5PEX12, PEX19, PEX10, PEX14, PEX13
PEX2PEX7No-4PEX14, PEX5L, PEX5, PEX13
PEX2PEX26No-1PEX19
PEX2PEX6No-2PEX5L, PEX5
PEX2PEX19Yesbinding6PEX13, PEX12, PEX5, PEX10, PEX5L, PEX14
PEX2PEX10Yesbinding6PEX19, PEX13, PEX12, PEX5, PEX5L, PEX14
PEX2PEX13Yesbinding6PEX19, PEX12, PEX5, PEX10, PEX5L, PEX14
PEX2PEX12Yesbinding6PEX19, PEX13, PEX5, PEX10, PEX5L, PEX14
PEX2PEX14Yesbinding6PEX19, PEX13, PEX12, PEX5, PEX10, PEX5L
PEX2PEX16No-1PEX19
PEX5PEX7Yesbinding2PEX14, PEX13
PEX5PEX26No-3PEX19, PEX6, PEX1
PEX5PEX6Yesbinding1PEX1
PEX5PEX19Yesbinding7PEX13, PEX12, PEX10, UBC, PEX2, PEX14, PEX3
PEX5PEX10Yesbinding5PEX14, PEX2, PEX12, PEX19, PEX13
PEX5PEX13Yesbinding8PEX19, PEX12, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
PEX5PEX12Yesbinding5PEX14, PEX2, PEX10, PEX19, PEX13
PEX5PEX14Yesbinding7PEX19, PEX13, PEX12, PEX10, UBC, PEX2, PEX7
PEX5PEX16No-1PEX19
PEX7PEX6No-2PEX5L, PEX5
PEX7PEX19No-4PEX14, PEX5L, PEX5, PEX13
PEX7PEX10No-4PEX14, PEX5L, PEX5, PEX13
PEX7PEX13Yesbinding3PEX14, PEX5L, PEX5
PEX7PEX12No-4PEX14, PEX5L, PEX5, PEX13
PEX7PEX14Yesbinding3PEX5L, PEX5, PEX13
PEX26PEX6Yesbinding1PEX1
PEX26PEX19Yesbinding0
PEX26PEX10No-1PEX19
PEX26PEX13No-2PEX19, PEX1
PEX26PEX12No-1PEX19
PEX26PEX14No-1PEX19
PEX26PEX16No-1PEX19
PEX6PEX19No-3PEX26, PEX5L, PEX5
PEX6PEX10No-2PEX5L, PEX5
PEX6PEX13No-3PEX5L, PEX5, PEX1
PEX6PEX12No-2PEX5L, PEX5
PEX6PEX14No-2PEX5L, PEX5
PEX19PEX10Yesbinding8PEX11G, PEX11A, PEX13, PEX12, PEX5, PEX5L, PEX2, PEX14
PEX19PEX13Yesbinding9PEX11G, PEX11A, PEX12, PEX5, PEX5L, PEX10, PEX2, PEX14, PEX3
PEX19PEX12Yesbinding8PEX11G, PEX13, PEX11A, PEX5, PEX10, PEX5L, PEX2, PEX14
PEX19PEX14Yesbinding10PEX11G, PEX13, PEX11A, ABCD3, PEX12, PEX5, PEX5L, UBC, PEX10, PEX2
PEX19PEX16Yesbinding0
PEX10PEX13Yesbinding8PEX11G, PEX11A, PEX12, PEX19, PEX5, PEX5L, PEX2, PEX14
PEX10PEX12Yesbinding8PEX11G, PEX13, PEX11A, PEX19, PEX5, PEX5L, PEX2, PEX14
PEX10PEX14Yesbinding8PEX11G, PEX13, PEX11A, PEX12, PEX19, PEX5, PEX5L, PEX2
PEX10PEX16No-1PEX19
PEX13PEX12Yesbinding8PEX11G, PEX11A, PEX19, PEX5, PEX5L, PEX10, PEX2, PEX14
PEX13PEX14Yesbinding9PEX19, PEX11A, PEX12, PEX11G, PEX5, PEX5L, PEX10, PEX2, PEX7
PEX13PEX16No-1PEX19
PEX12PEX14Yesbinding8PEX11G, PEX13, PEX11A, PEX19, PEX5, PEX5L, PEX10, PEX2
PEX12PEX16No-1PEX19
PEX14PEX16No-1PEX19

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Gene1Gene2Direct InteractionComplexesNumber of shared interactorsShared genes in interaction
PEX1PEX26YesPex26-Pex6-Pex1 complex1PEX6
PEX1PEX6YesPex26-Pex6-Pex1 complex1PEX26
PEX26PEX6YesPex26-Pex6-Pex1 complex1PEX1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CENSUS
Interactions from PDB
Gene1Gene2InteractionNumber of common interactorsCommon genes in interaction
PEX3PEX19Yes2PEX19, PEX3
PEX3PEX14No1PEX19
PEX5PEX19No1PEX14
PEX5PEX14Yes2PEX14, PEX5
PEX19PEX14Yes2PEX19, PEX14

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Peroxisomehsa041466.3414PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1

NET-GE enrichment

Term New enriched termICP valueGenes
Fatty acid degradation (hsa00071) NEW7.150.0PEX19, PEX14, PEX7, PEX5
Transport and catabolismNEW3.490.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
Biosynthesis of unsaturated fatty acids (hsa01040) NEW8.380.03PEX7, PEX5
Cellular ProcessesNEW2.220.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
Peroxisome (hsa04146) -6.340.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
ABC-family proteins mediated transportR-HSA-3825567.592PEX19, PEX3
ABC transporters in lipid homeostasisR-HSA-13690629.082PEX19, PEX3
Transmembrane transport of small moleculesR-HSA-3825513.792PEX19, PEX3

NET-GE enrichment

Term New enriched termICP valueGenes
PPARA activates gene expression (R-HSA-1989781) NEW6.180.001PEX19, PEX14, PEX5, PEX13
ABC-family proteins mediated transport (R-HSA-382556) -7.590.048PEX19, PEX3
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (R-HSA-400206) NEW6.140.001PEX19, PEX14, PEX5, PEX13
Fatty acid, triacylglycerol, and ketone body metabolism (R-HSA-535734) NEW5.440.006PEX19, PEX14, PEX5, PEX13
Peroxisomal lipid metabolism (R-HSA-390918) NEW8.590.0PEX19, PEX14, PEX7, PEX5
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism (R-HSA-2046104) NEW9.280.003PEX7, PEX5
Beta-oxidation of very long chain fatty acids (R-HSA-390247) NEW10.40.0PEX14, PEX7, PEX5
ABC transporters in lipid homeostasis (R-HSA-1369062) -9.080.006PEX19, PEX3
Transmembrane transport of small molecules (R-HSA-382551) -3.790.021PEX19, PEX3
alpha-linolenic acid (ALA) metabolism (R-HSA-2046106) NEW9.280.003PEX7, PEX5
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.1814PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
protein binding (GO:0005515) 0.4614PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
protein C-terminus binding (GO:0008022) 4.57PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX1
enzyme binding (GO:0019899) 2.274PEX19, PEX7, PEX26, PEX5
cation binding (GO:0043169) 1.43PEX12, PEX2, PEX10
peptide binding (GO:0042277) 4.223PEX19, PEX7, PEX5
peroxisome targeting sequence binding (GO:0000268) 8.133PEX19, PEX7, PEX5
transition metal ion binding (GO:0046914) 2.483PEX12, PEX2, PEX10
amide binding (GO:0033218) 4.143PEX19, PEX7, PEX5
ion binding (GO:0043167) 1.363PEX12, PEX2, PEX10
protein N-terminus binding (GO:0047485) 5.113PEX19, PEX14, PEX5
catalytic activity (GO:0003824) 1.053PEX6, PEX12, PEX1
macromolecular complex binding (GO:0044877) 2.613PEX26, PEX6, PEX1
zinc ion binding (GO:0008270) 2.663PEX12, PEX2, PEX10
protein complex binding (GO:0032403) 3.093PEX26, PEX6, PEX1
protein dimerization activity (GO:0046983) 2.723PEX11B, PEX7, PEX3
metal ion binding (GO:0046872) 1.413PEX12, PEX2, PEX10
signal sequence binding (GO:0005048) 6.073PEX19, PEX7, PEX5
purine ribonucleoside triphosphate binding (GO:0035639) 2.222PEX6, PEX1
ATPase activity (GO:0016887) 3.652PEX6, PEX1
heterocyclic compound binding (GO:1901363) 1.062PEX6, PEX1
purine nucleoside binding (GO:0001883) 2.222PEX6, PEX1
nucleoside binding (GO:0001882) 2.212PEX6, PEX1
ATPase activity, coupled (GO:0042623) 3.972PEX6, PEX1
nucleotide binding (GO:0000166) 1.962PEX6, PEX1
nucleoside phosphate binding (GO:1901265) 1.962PEX6, PEX1
ribonucleoside binding (GO:0032549) 2.222PEX6, PEX1
purine nucleotide binding (GO:0017076) 2.192PEX6, PEX1
ATP binding (GO:0005524) 2.432PEX6, PEX1
protein homodimerization activity (GO:0042803) 3.162PEX11B, PEX7
hydrolase activity (GO:0016787) 1.92PEX6, PEX1
ATPase binding (GO:0051117) 5.412PEX19, PEX26
nucleoside-triphosphatase activity (GO:0017111) 3.092PEX6, PEX1
small molecule binding (GO:0036094) 1.892PEX6, PEX1
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818) 3.032PEX6, PEX1
adenyl nucleotide binding (GO:0030554) 2.42PEX6, PEX1
carbohydrate derivative binding (GO:0097367) 2.032PEX6, PEX1
organic cyclic compound binding (GO:0097159) 1.052PEX6, PEX1
hydrolase activity, acting on acid anhydrides (GO:0016817) 3.032PEX6, PEX1
pyrophosphatase activity (GO:0016462) 3.042PEX6, PEX1
adenyl ribonucleotide binding (GO:0032559) 2.412PEX6, PEX1
identical protein binding (GO:0042802) 2.632PEX11B, PEX7
purine ribonucleotide binding (GO:0032555) 2.22PEX6, PEX1
purine ribonucleoside binding (GO:0032550) 2.222PEX6, PEX1
ribonucleotide binding (GO:0032553) 2.192PEX6, PEX1

NET-GE enrichment

Term New enriched termICP valueGenes
protein C-terminus binding (GO:0008022) -4.50.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX2, PEX1
peptide binding (GO:0042277) -4.220.042PEX19, PEX13, PEX12, PEX5, PEX14, PEX7
signal sequence binding (GO:0005048) -6.070.0PEX19, PEX7, PEX5
protein N-terminus binding (GO:0047485) -5.110.002PEX19, PEX14, PEX5
protein binding (GO:0005515) -0.460.002PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
amide binding (GO:0033218) -4.140.044PEX19, PEX13, PEX12, PEX5, PEX14, PEX7
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor (GO:0016634) NEW7.540.009PEX7, PEX5
peroxisome matrix targeting signal-1 binding (GO:0005052) NEW9.050.0PEX19, PEX5
ATPase binding (GO:0051117) -5.410.029PEX19, PEX26
peroxisome targeting sequence binding (GO:0000268) -8.130.0PEX19, PEX7, PEX5
protein dimerization activity (GO:0046983) -2.720.031PEX19, PEX13, PEX11B, PEX12, PEX5, PEX10, PEX3, PEX14, PEX7
protein homodimerization activity (GO:0042803) -3.160.012PEX19, PEX13, PEX11B, PEX12, PEX5, PEX10, PEX14, PEX7
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
organelle organization (GO:0006996) 2.0214PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cellular process (GO:0009987) 0.2614PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cellular component organization (GO:0016043) 1.2414PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cellular component organization or biogenesis (GO:0071840) 1.2214PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
protein localization (GO:0008104) 2.3613PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
establishment of localization (GO:0051234) 1.4813PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
transport (GO:0006810) 1.5113PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
establishment of protein localization (GO:0045184) 2.5313PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
peroxisome organization (GO:0007031) 6.4713PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
single-organism cellular process (GO:0044763) 0.6513PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
organic substance transport (GO:0071702) 2.1513PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein transport (GO:0015031) 2.6213PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
macromolecule localization (GO:0033036) 2.3413PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
localization (GO:0051179) 1.413PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
single-organism process (GO:0044699) 0.4813PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cellular localization (GO:0051641) 2.3213PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein transmembrane transport (GO:0071806) 5.812PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
intracellular transport (GO:0046907) 2.6712PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
cellular macromolecule localization (GO:0070727) 3.112PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
establishment of protein localization to peroxisome (GO:0072663) 7.0212PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein targeting to peroxisome (GO:0006625) 7.0212PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
intracellular protein transport (GO:0006886) 3.212PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
cellular protein localization (GO:0034613) 3.1112PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
establishment of protein localization to organelle (GO:0072594) 3.9212PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein targeting (GO:0006605) 4.0812PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
intracellular protein transmembrane transport (GO:0065002) 5.9412PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
single-organism organelle organization (GO:1902589) 2.6812PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
single-organism localization (GO:1902578) 2.0912PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein localization to peroxisome (GO:0072662) 7.0212PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein localization to organelle (GO:0033365) 3.5712PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
single-organism cellular localization (GO:1902580) 3.1612PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
transmembrane transport (GO:0055085) 2.7212PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
establishment of localization in cell (GO:0051649) 2.4712PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
peroxisomal transport (GO:0043574) 6.9612PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
single-organism intracellular transport (GO:1902582) 3.5911PEX19, PEX16, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
single-organism transport (GO:0044765) 2.1811PEX19, PEX16, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein import (GO:0017038) 4.8511PEX19, PEX16, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
intracellular protein transmembrane import (GO:0044743) 6.1211PEX19, PEX16, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein import into peroxisome matrix (GO:0016558) 7.439PEX16, PEX26, PEX12, PEX5, PEX10, PEX1, PEX2, PEX14, PEX7
biological regulation (GO:0065007) 0.398PEX19, PEX13, PEX11B, PEX5, PEX6, PEX2, PEX14, PEX3
regulation of biological process (GO:0050789) 0.456PEX13, PEX11B, PEX5, PEX2, PEX14, PEX3
regulation of cellular process (GO:0050794) 0.56PEX13, PEX11B, PEX5, PEX2, PEX14, PEX3
organic substance metabolic process (GO:0071704) 0.635PEX7, PEX2, PEX12, PEX5, PEX13
primary metabolic process (GO:0044238) 0.695PEX7, PEX2, PEX12, PEX5, PEX13
peroxisomal membrane transport (GO:0015919) 7.785PEX16, PEX19, PEX26, PEX5, PEX3
establishment of protein localization to membrane (GO:0090150) 4.145PEX16, PEX19, PEX26, PEX5, PEX3
protein targeting to membrane (GO:0006612) 4.655PEX16, PEX19, PEX26, PEX5, PEX3
cellular metabolic process (GO:0044237) 0.695PEX7, PEX2, PEX12, PEX5, PEX13
protein import into peroxisome membrane (GO:0045046) 7.945PEX16, PEX19, PEX26, PEX5, PEX3
membrane organization (GO:0061024) 3.045PEX16, PEX19, PEX26, PEX5, PEX3
single-organism membrane organization (GO:0044802) 3.195PEX16, PEX19, PEX26, PEX5, PEX3
protein localization to membrane (GO:0072657) 3.955PEX16, PEX19, PEX26, PEX5, PEX3
metabolic process (GO:0008152) 0.585PEX7, PEX2, PEX12, PEX5, PEX13
lipid oxidation (GO:0034440) 5.474PEX2, PEX7, PEX5, PEX13
fatty acid metabolic process (GO:0006631) 4.034PEX2, PEX7, PEX5, PEX13
carboxylic acid metabolic process (GO:0019752) 3.124PEX2, PEX7, PEX5, PEX13
movement of cell or subcellular component (GO:0006928) 2.614PEX7, PEX14, PEX5, PEX13
cellular catabolic process (GO:0044248) 2.624PEX2, PEX7, PEX5, PEX13
fatty acid catabolic process (GO:0009062) 5.484PEX2, PEX7, PEX5, PEX13
small molecule metabolic process (GO:0044281) 2.384PEX2, PEX7, PEX5, PEX13
small molecule catabolic process (GO:0044282) 3.994PEX2, PEX7, PEX5, PEX13
cellular lipid catabolic process (GO:0044242) 4.734PEX2, PEX7, PEX5, PEX13
single-organism catabolic process (GO:0044712) 3.214PEX2, PEX7, PEX5, PEX13
single-organism metabolic process (GO:0044710) 1.634PEX2, PEX7, PEX5, PEX13
catabolic process (GO:0009056) 2.384PEX2, PEX7, PEX5, PEX13
lipid catabolic process (GO:0016042) 4.214PEX2, PEX7, PEX5, PEX13
regulation of biological quality (GO:0065008) 1.684PEX19, PEX11B, PEX2, PEX6
protein to membrane docking (GO:0022615) 7.654PEX16, PEX14, PEX5, PEX13
lipid metabolic process (GO:0006629) 2.684PEX2, PEX7, PEX5, PEX13
organic substance catabolic process (GO:1901575) 2.454PEX2, PEX7, PEX5, PEX13
monocarboxylic acid metabolic process (GO:0032787) 3.574PEX2, PEX7, PEX5, PEX13
monocarboxylic acid catabolic process (GO:0072329) 5.264PEX2, PEX7, PEX5, PEX13
oxoacid metabolic process (GO:0043436) 3.124PEX2, PEX7, PEX5, PEX13
fatty acid oxidation (GO:0019395) 5.484PEX2, PEX7, PEX5, PEX13
cellular lipid metabolic process (GO:0044255) 2.924PEX2, PEX7, PEX5, PEX13
lipid modification (GO:0030258) 4.374PEX2, PEX7, PEX5, PEX13
oxidation-reduction process (GO:0055114) 2.914PEX2, PEX7, PEX5, PEX13
membrane docking (GO:0022406) 5.494PEX16, PEX14, PEX5, PEX13
organic acid metabolic process (GO:0006082) 3.014PEX2, PEX7, PEX5, PEX13
carboxylic acid catabolic process (GO:0046395) 4.584PEX2, PEX7, PEX5, PEX13
organic acid catabolic process (GO:0016054) 4.444PEX2, PEX7, PEX5, PEX13
cellular component assembly (GO:0022607) 2.143PEX11B, PEX14, PEX5
fatty acid beta-oxidation (GO:0006635) 5.783PEX2, PEX7, PEX5
macromolecular complex subunit organization (GO:0043933) 2.143PEX11B, PEX14, PEX5
neuron migration (GO:0001764) 5.03PEX7, PEX5, PEX13
mitochondrion organization (GO:0007005) 3.693PEX13, PEX5, PEX3
protein complex subunit organization (GO:0071822) 2.63PEX11B, PEX14, PEX5
peroxisome membrane biogenesis (GO:0016557) 8.343PEX19, PEX16, PEX3
macromolecular complex assembly (GO:0065003) 2.553PEX11B, PEX14, PEX5
membrane biogenesis (GO:0044091) 8.123PEX19, PEX16, PEX3
negative regulation of biological process (GO:0048519) 1.333PEX2, PEX14, PEX5
cell migration (GO:0016477) 3.123PEX7, PEX5, PEX13
protein oligomerization (GO:0051259) 3.713PEX11B, PEX14, PEX5
protein complex assembly (GO:0006461) 2.783PEX11B, PEX14, PEX5
cellular component disassembly (GO:0022411) 3.523PEX14, PEX13, PEX3
organelle localization (GO:0051640) 3.943PEX14, PEX13, PEX1
locomotion (GO:0040011) 2.913PEX7, PEX5, PEX13
microtubule-based process (GO:0007017) 3.543PEX14, PEX13, PEX1
cell motility (GO:0048870) 3.023PEX7, PEX5, PEX13
regulation of protein stability (GO:0031647) 4.333PEX19, PEX2, PEX6
cellular component biogenesis (GO:0044085) 4.463PEX19, PEX16, PEX3
protein import into peroxisome matrix, docking (GO:0016560) 8.343PEX14, PEX5, PEX13
protein import into peroxisome matrix, translocation (GO:0016561) 8.633PEX6, PEX14, PEX5
negative regulation of cellular process (GO:0048523) 1.413PEX2, PEX14, PEX5
negative regulation of cellular metabolic process (GO:0031324) 2.012PEX2, PEX14
regulation of binding (GO:0051098) 4.082PEX19, PEX14
negative regulation of metabolic process (GO:0009892) 1.932PEX2, PEX14
regulation of primary metabolic process (GO:0080090) 1.082PEX2, PEX14
regulation of metabolic process (GO:0019222) 1.022PEX2, PEX14
regulation of response to external stimulus (GO:0032101) 3.062PEX3, PEX13
negative regulation of cellular biosynthetic process (GO:0031327) 2.492PEX2, PEX14
regulation of cellular biosynthetic process (GO:0031326) 1.382PEX2, PEX14
very long-chain fatty acid metabolic process (GO:0000038) 6.332PEX2, PEX5
regulation of response to stimulus (GO:0048583) 1.542PEX13, PEX3
negative regulation of binding (GO:0051100) 4.852PEX19, PEX14
negative regulation of cellular component organization (GO:0051129) 3.352PEX14, PEX5
regulation of cellular component organization (GO:0051128) 2.012PEX14, PEX5
mitophagy in response to mitochondrial depolarization (GO:0098779) 4.852PEX13, PEX3
negative regulation of gene expression (GO:0010629) 2.482PEX2, PEX14
microtubule-based peroxisome localization (GO:0060152) 9.042PEX13, PEX1
forebrain cell migration (GO:0021885) 5.922PEX5, PEX13
peroxisome localization (GO:0060151) 9.042PEX13, PEX1
regulation of defense response (GO:0031347) 3.112PEX13, PEX3
regulation of defense response to virus (GO:0050688) 4.532PEX13, PEX3
negative regulation of macromolecule metabolic process (GO:0010605) 2.012PEX2, PEX14
negative regulation of biosynthetic process (GO:0009890) 2.472PEX2, PEX14
peroxisome fission (GO:0016559) 7.432PEX19, PEX11B
regulation of cellular component biogenesis (GO:0044087) 3.082PEX14, PEX5
regulation of viral process (GO:0050792) 3.892PEX13, PEX3
protein homooligomerization (GO:0051260) 4.212PEX11B, PEX14
negative regulation of cellular macromolecule biosynthetic process (GO:2000113) 2.62PEX2, PEX14
mitochondrion disassembly (GO:0061726) 4.632PEX13, PEX3
positive regulation of defense response to virus by host (GO:0002230) 4.982PEX3, PEX13
regulation of immune system process (GO:0002682) 2.52PEX3, PEX13
negative regulation of molecular function (GO:0044092) 2.742PEX19, PEX14
regulation of molecular function (GO:0065009) 1.782PEX19, PEX14
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.462PEX2, PEX14
negative regulation of protein oligomerization (GO:0032460) 7.242PEX14, PEX5
cerebral cortex cell migration (GO:0021795) 6.362PEX5, PEX13
regulation of protein homooligomerization (GO:0032462) 6.962PEX14, PEX5
regulation of protein oligomerization (GO:0032459) 6.172PEX14, PEX5
multicellular organismal process (GO:0032501) 1.452PEX7, PEX5
negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 2.552PEX2, PEX14
negative regulation of protein homooligomerization (GO:0032463) 7.782PEX14, PEX5
regulation of macromolecule metabolic process (GO:0060255) 1.082PEX2, PEX14
regulation of response to biotic stimulus (GO:0002831) 4.32PEX13, PEX3
macroautophagy (GO:0016236) 4.32PEX3, PEX13
negative regulation of protein complex assembly (GO:0031333) 5.072PEX14, PEX5
regulation of biosynthetic process (GO:0009889) 1.372PEX2, PEX14
regulation of nucleic acid-templated transcription (GO:1903506) 1.552PEX2, PEX14
organelle disassembly (GO:1903008) 4.522PEX13, PEX3
regulation of cellular metabolic process (GO:0031323) 1.072PEX2, PEX14
regulation of symbiosis, encompassing mutualism through parasitism (GO:0043903) 3.822PEX3, PEX13
regulation of multi-organism process (GO:0043900) 3.62PEX13, PEX3
regulation of protein homotetramerization (GO:1901093) 9.042PEX14, PEX5
negative regulation of protein homotetramerization (GO:1901094) 9.042PEX14, PEX5
regulation of nitrogen compound metabolic process (GO:0051171) 1.362PEX2, PEX14
negative regulation of nitrogen compound metabolic process (GO:0051172) 2.472PEX2, PEX14
regulation of RNA biosynthetic process (GO:2001141) 1.552PEX2, PEX14
regulation of response to stress (GO:0080134) 2.532PEX3, PEX13
regulation of protein complex assembly (GO:0043254) 3.832PEX14, PEX5
negative regulation of nucleic acid-templated transcription (GO:1903507) 2.712PEX2, PEX14
telencephalon cell migration (GO:0022029) 5.992PEX5, PEX13
regulation of defense response to virus by host (GO:0050691) 4.892PEX13, PEX3
autophagy (GO:0006914) 3.822PEX13, PEX3
protein stabilization (GO:0050821) 4.862PEX19, PEX6
mitophagy (GO:0000422) 4.632PEX3, PEX13
macromitophagy (GO:0000423) 4.852PEX3, PEX13
negative regulation of RNA metabolic process (GO:0051253) 2.662PEX2, PEX14
regulation of RNA metabolic process (GO:0051252) 1.522PEX2, PEX14
negative regulation of protein tetramerization (GO:1901091) 9.042PEX14, PEX5
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.432PEX2, PEX14
regulation of gene expression (GO:0010468) 1.372PEX2, PEX14
regulation of transcription, DNA-templated (GO:0006355) 1.562PEX2, PEX14
regulation of immune effector process (GO:0002697) 3.712PEX3, PEX13
regulation of macromolecule biosynthetic process (GO:0010556) 1.432PEX2, PEX14
regulation of protein tetramerization (GO:1901090) 9.042PEX14, PEX5
organelle fission (GO:0048285) 3.792PEX19, PEX11B
negative regulation of RNA biosynthetic process (GO:1902679) 2.72PEX2, PEX14
negative regulation of transcription, DNA-templated (GO:0045892) 2.752PEX2, PEX14
xenophagy (GO:0098792) 5.172PEX3, PEX13
negative regulation of macromolecule biosynthetic process (GO:0010558) 2.532PEX2, PEX14

NET-GE enrichment

Term New enriched termICP valueGenes
lipid oxidation (GO:0034440) -5.470.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
fatty acid metabolic process (GO:0006631) -4.030.001PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
regulation of protein stability (GO:0031647) -4.330.043PEX19, PEX2, PEX6
establishment of localization (GO:0051234) -1.480.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
fatty acid beta-oxidation (GO:0006635) -5.780.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
peroxisomal membrane transport (GO:0015919) -7.780.0PEX16, PEX19, PEX26, PEX5, PEX3
establishment of protein localization to peroxisome (GO:0072663) -7.020.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein targeting to membrane (GO:0006612) -4.650.0PEX16, PEX19, PEX26, PEX5, PEX3
regulation of protein homooligomerization (GO:0032462) -6.960.018PEX14, PEX5
membrane docking (GO:0022406) -5.490.0PEX16, PEX19, PEX14, PEX5, PEX13
fatty acid catabolic process (GO:0009062) -5.480.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
cytoplasmic transport (GO:0016482) NEW4.980.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
microtubule-based peroxisome localization (GO:0060152) -9.040.001PEX13, PEX1
small molecule catabolic process (GO:0044282) -3.990.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
peroxisome localization (GO:0060151) -9.040.001PEX13, PEX1
fatty acid alpha-oxidation (GO:0001561) NEW7.780.016PEX7, PEX13
cellular lipid catabolic process (GO:0044242) -4.730.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
lipid catabolic process (GO:0016042) -4.210.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
purine nucleoside monophosphate metabolic process (GO:0009126) NEW4.690.036PEX19, PEX13, PEX5, PEX6, PEX14, PEX1
peroxisome organization (GO:0007031) -6.470.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cellular component organization or biogenesis (GO:0071840) -1.220.0PEX19, PEX16, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
protein localization to endoplasmic reticulum (GO:0070972) NEW5.040.013PEX19, PEX16
protein transmembrane transport (GO:0071806) -5.80.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
peroxisome fission (GO:0016559) -7.430.0PEX19, PEX11B, PEX13, PEX5
protein import into peroxisome matrix (GO:0016558) -7.430.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX10, PEX1, PEX2, PEX14, PEX7
peroxisome membrane biogenesis (GO:0016557) -8.340.0PEX19, PEX16, PEX3
intracellular protein transport (GO:0006886) -3.20.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cellular component organization (GO:0016043) -1.240.0PEX19, PEX16, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
localization (GO:0051179) -1.40.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
intracellular protein transmembrane transport (GO:0065002) -5.940.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
neuron migration (GO:0001764) -5.00.001PEX13, PEX5, PEX10, PEX2, PEX14, PEX7
membrane biogenesis (GO:0044091) -8.120.0PEX19, PEX16, PEX3
ether lipid biosynthetic process (GO:0008611) NEW8.340.006PEX7, PEX5
establishment of protein localization to organelle (GO:0072594) -3.920.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
glycerol ether biosynthetic process (GO:0046504) NEW8.340.006PEX7, PEX5
peroxisomal transport (GO:0043574) -6.960.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
establishment of localization in cell (GO:0051649) -2.470.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
negative regulation of protein oligomerization (GO:0032460) -7.240.008PEX14, PEX5
negative regulation of protein homooligomerization (GO:0032463) -7.780.008PEX14, PEX5
organelle fission (GO:0048285) -3.790.026PEX19, PEX13, PEX11B, PEX5, PEX10, PEX14
transport (GO:0006810) -1.510.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
purine ribonucleoside monophosphate metabolic process (GO:0009167) NEW4.70.036PEX19, PEX13, PEX5, PEX6, PEX14, PEX1
ribonucleoside monophosphate metabolic process (GO:0009161) NEW4.620.048PEX19, PEX13, PEX5, PEX6, PEX14, PEX1
protein targeting to peroxisome (GO:0006625) -7.020.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
monocarboxylic acid catabolic process (GO:0072329) -5.260.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
protein import (GO:0017038) -4.850.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
regulation of protein homotetramerization (GO:1901093) -9.040.0PEX14, PEX5
protein targeting (GO:0006605) -4.080.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
regulation of protein tetramerization (GO:1901090) -9.040.0PEX14, PEX5
negative regulation of protein tetramerization (GO:1901091) -9.040.0PEX14, PEX5
single-organism transport (GO:0044765) -2.180.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
alpha-linolenic acid metabolic process (GO:0036109) NEW7.160.036PEX7, PEX5
negative regulation of protein homotetramerization (GO:1901094) -9.040.0PEX14, PEX5
very long-chain fatty acid metabolic process (GO:0000038) -6.330.0PEX19, PEX7, PEX2, PEX5
fatty acid oxidation (GO:0019395) -5.480.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
bile acid metabolic process (GO:0008206) NEW6.150.026PEX2, PEX7, PEX5
monocarboxylic acid metabolic process (GO:0032787) -3.570.014PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
lipid modification (GO:0030258) -4.370.001PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
transmembrane transport (GO:0055085) -2.720.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
intracellular protein transmembrane import (GO:0044743) -6.120.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
lipid biosynthetic process (GO:0008610) NEW3.490.013PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
organelle organization (GO:0006996) -2.020.0PEX19, PEX16, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
establishment of protein localization (GO:0045184) -2.530.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
replacement ossification (GO:0036075) NEW6.470.013PEX14, PEX7, PEX5
organic substance transport (GO:0071702) -2.150.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
intracellular transport (GO:0046907) -2.670.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
endochondral ossification (GO:0001958) NEW6.470.013PEX14, PEX7, PEX5
carboxylic acid catabolic process (GO:0046395) -4.580.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
organic acid catabolic process (GO:0016054) -4.440.0PEX19, PEX13, PEX12, PEX5, PEX2, PEX14, PEX7
ether lipid metabolic process (GO:0046485) NEW7.940.02PEX7, PEX5
single-organism cellular process (GO:0044763) -0.650.033PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
protein import into peroxisome membrane (GO:0045046) -7.940.0PEX16, PEX19, PEX26, PEX5, PEX3
ether biosynthetic process (GO:1901503) NEW8.340.006PEX7, PEX5
cellular lipid biosynthetic process (GO:0097384) NEW8.340.006PEX7, PEX5
cellular component biogenesis (GO:0044085) -4.460.011PEX19, PEX16, PEX3
protein to membrane docking (GO:0022615) -7.650.0PEX16, PEX19, PEX14, PEX5, PEX13
protein import into peroxisome matrix, docking (GO:0016560) -8.340.0PEX14, PEX5, PEX13
establishment of protein localization to membrane (GO:0090150) -4.140.012PEX16, PEX19, PEX26, PEX5, PEX3
protein transport (GO:0015031) -2.620.0PEX19, PEX16, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1
single-organism intracellular transport (GO:1902582) -3.590.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) NEW7.160.0PEX14, PEX7, PEX5
protein import into peroxisome matrix, translocation (GO:0016561) -8.630.0PEX6, PEX14, PEX5
regulation of cellular component size (GO:0032535) NEW4.210.008PEX14, PEX19, PEX10, PEX11B, PEX13
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
intracellular membrane-bounded organelle (GO:0043231) 0.614PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cell part (GO:0044464) 0.1114PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
peroxisome (GO:0005777) 5.0114PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cytoplasmic part (GO:0044444) 0.8214PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
intracellular organelle part (GO:0044446) 0.8114PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
microbody (GO:0042579) 4.9314PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
intracellular organelle (GO:0043229) 0.5114PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
intracellular part (GO:0044424) 0.2814PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
peroxisomal part (GO:0044439) 5.2814PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
microbody part (GO:0044438) 5.2814PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
membrane-bounded organelle (GO:0043227) 0.4714PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
organelle (GO:0043226) 0.414PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
organelle part (GO:0044422) 0.7914PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
peroxisomal membrane (GO:0005778) 5.7613PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX11B, PEX3
organelle membrane (GO:0031090) 1.9713PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX11B, PEX3
whole membrane (GO:0098805) 2.8513PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX11B, PEX3
membrane (GO:0016020) 0.6813PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX11B, PEX3
microbody membrane (GO:0031903) 5.7613PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX11B, PEX3
bounding membrane of organelle (GO:0098588) 2.3913PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX11B, PEX3
membrane part (GO:0044425) 0.9510PEX19, PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX14, PEX26, PEX3
integral component of membrane (GO:0016021) 1.1410PEX19, PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX14, PEX26, PEX3
intrinsic component of membrane (GO:0031224) 1.1310PEX19, PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX14, PEX26, PEX3
intrinsic component of peroxisomal membrane (GO:0031231) 7.168PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX26, PEX3
integral component of peroxisomal membrane (GO:0005779) 7.168PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX26, PEX3
integral component of organelle membrane (GO:0031301) 4.858PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX26, PEX3
intrinsic component of organelle membrane (GO:0031300) 4.88PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX26, PEX3
protein complex (GO:0043234) 1.517PEX19, PEX11B, PEX12, PEX5, PEX2, PEX14, PEX3
macromolecular complex (GO:0032991) 1.357PEX19, PEX11B, PEX12, PEX5, PEX2, PEX14, PEX3
cytosol (GO:0005829) 1.686PEX19, PEX5, PEX6, PEX3, PEX7, PEX1
cytoplasm (GO:0005737) 1.015PEX19, PEX6, PEX7, PEX5, PEX1
nuclear part (GO:0044428) 1.554PEX19, PEX14, PEX2, PEX3
intracellular (GO:0005622) 2.373PEX14, PEX10, PEX5
peroxisomal matrix (GO:0005782) 6.02PEX7, PEX5
endoplasmic reticulum (GO:0005783) 2.562PEX16, PEX3
organelle lumen (GO:0043233) 3.052PEX7, PEX5
extracellular exosome (GO:0070062) 1.892PEX11B, PEX1
nucleus (GO:0005634) 1.072PEX19, PEX14
membrane-enclosed lumen (GO:0031974) 3.052PEX7, PEX5
membrane-bounded vesicle (GO:0031988) 1.712PEX11B, PEX1
nucleoplasm (GO:0005654) 1.892PEX19, PEX3
intracellular organelle lumen (GO:0070013) 3.052PEX7, PEX5
microbody lumen (GO:0031907) 6.02PEX7, PEX5
extracellular organelle (GO:0043230) 1.892PEX11B, PEX1
extracellular vesicle (GO:1903561) 1.892PEX11B, PEX1
extracellular region part (GO:0044421) 1.572PEX11B, PEX1
vesicle (GO:0031982) 1.642PEX11B, PEX1

NET-GE enrichment

Term New enriched termICP valueGenes
integral component of peroxisomal membrane (GO:0005779) -7.160.0PEX19, PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX26, PEX3
peroxisomal membrane (GO:0005778) -5.760.0PEX19, PEX16, PEX13, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX3
peroxisomal matrix (GO:0005782) -6.00.017PEX14, PEX19, PEX12, PEX7, PEX5
intracellular membrane-bounded organelle (GO:0043231) -0.60.001PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
microbody membrane (GO:0031903) -5.760.0PEX19, PEX16, PEX13, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX3
bounding membrane of organelle (GO:0098588) -2.390.0PEX19, PEX16, PEX13, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX3
membrane (GO:0016020) -0.680.019PEX19, PEX16, PEX13, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX1, PEX2, PEX14, PEX3
peroxisome (GO:0005777) -5.010.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX14, PEX11B, PEX7, PEX1
intracellular organelle (GO:0043229) -0.510.004PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
intracellular organelle part (GO:0044446) -0.810.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
microbody (GO:0042579) -4.930.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
cytoplasmic part (GO:0044444) -0.820.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
integral component of organelle membrane (GO:0031301) -4.850.0PEX19, PEX16, PEX13, PEX11B, PEX12, PEX10, PEX2, PEX14, PEX26, PEX3
intrinsic component of membrane (GO:0031224) -1.130.029PEX19, PEX14, PEX5
microbody lumen (GO:0031907) -6.00.017PEX14, PEX19, PEX12, PEX7, PEX5
peroxisomal part (GO:0044439) -5.280.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
microbody part (GO:0044438) -5.280.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
membrane-bounded organelle (GO:0043227) -0.470.007PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
organelle (GO:0043226) -0.40.027PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
organelle part (GO:0044422) -0.790.0PEX19, PEX16, PEX13, PEX26, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX11B, PEX7, PEX1
organelle membrane (GO:0031090) -1.970.001PEX19, PEX16, PEX13, PEX11B, PEX12, PEX5, PEX6, PEX10, PEX3, PEX2, PEX14, PEX7, PEX1