Gene table of ALX4 : ALX homeobox 4

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ALX4	OMIM link	Number of associated genes	genes
PS136760	FRONTONASAL DYSPLASIA	ClinVar, OMIM	link to OMIM	3	ALX3, ALX4, ALX1
609597	PARIETAL FORAMINA 2	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	ALX4
615529	CRANIOSYNOSTOSIS 5, SUSCEPTIBILITY TO	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	ALX4

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
nucleic acid binding transcription factor activity	GO:0001071	2.65
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
double-stranded DNA binding	GO:0003690	3.09
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
regulatory region nucleic acid binding	GO:0001067	3.03
protein domain specific binding	GO:0019904	3.32
HMG box domain binding	GO:0071837	6.85
transcription regulatory region DNA binding	GO:0044212	3.03
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
protein dimerization activity	GO:0046983	2.72
protein heterodimerization activity	GO:0046982	3.64
binding	GO:0005488	0.18