Gene table of ASNS : asparagine synthetase (glutamine-hydrolyzing)

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ASNS	OMIM link	Number of associated genes	genes
615574	ASPARAGINE SYNTHETASE DEFICIENCY	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	ASNS

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Alanine, aspartate and glutamate metabolism	hsa00250	7.64
Metabolic pathways	hsa01100	2.49

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
PERK regulates gene expression	R-HSA-381042	8.18
Unfolded Protein Response (UPR)	R-HSA-381119	6.56
Metabolism of amino acids and derivatives	R-HSA-71291	5.4
ATF4 activates genes	R-HSA-380994	8.34
Metabolism of proteins	R-HSA-392499	3.41
Metabolism	R-HSA-1430728	2.34
Amino acid synthesis and interconversion (transamination)	R-HSA-70614	8.89

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
ATP binding	GO:0005524	2.43
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
nucleotide binding	GO:0000166	1.96
ligase activity, forming carbon-nitrogen bonds	GO:0016879	5.7
purine nucleoside binding	GO:0001883	2.22
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
cofactor binding	GO:0048037	4.16
ligase activity	GO:0016874	3.72
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
adenyl ribonucleotide binding	GO:0032559	2.41
	GO:0004066	9.05
protein binding	GO:0005515	0.46
purine ribonucleotide binding	GO:0032555	2.2
protein dimerization activity	GO:0046983	2.72
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	GO:0016884	7.25