Gene table of CHRNA5 : cholinergic receptor nicotinic alpha 5 subunit

Gene-disease associations table

Disease IDDisease nameSource of annotation with CHRNA5OMIM linkNumber of associated genesgenes
612052SMOKING AS A QUANTITATIVE TRAIT LOCUS 3ClinVar, OMIM link to OMIM 2CHRNA5, CHRNA3

Download the gene annotation in CSV format

Annotation of the gene CHRNA5

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation

The gene is in the tandem Group 676, together with the genes:

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Neuroactive ligand-receptor interactionhsa040804.58
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Acetylcholine Binding And Downstream EventsR-HSA-1814319.18
Activation of Nicotinic Acetylcholine ReceptorsR-HSA-6296029.18
Highly calcium permeable nicotinic acetylcholine receptorsR-HSA-6295979.81
Highly calcium permeable postsynaptic nicotinic acetylcholine receptorsR-HSA-6295949.52
Postsynaptic nicotinic acetylcholine receptorsR-HSA-6223279.18
Presynaptic nicotinic acetylcholine receptorsR-HSA-6223239.4
Neuronal SystemR-HSA-1123164.82
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellR-HSA-1123145.85
Transmission across Chemical SynapsesR-HSA-1123155.28
Associated GO terms for Molecular function
GO termGO IDGO IC
cation channel activityGO:00052614.04
acetylcholine receptor activityGO:00154646.3
molecular transducer activityGO:00600892.32
receptor activityGO:00048722.32
signal transducer activityGO:00048712.28
signaling receptor activityGO:00380232.49
ammonium ion bindingGO:00704055.81
protein heterodimerization activityGO:00469823.64
ligand-gated ion channel activityGO:00152764.8
ion bindingGO:00431671.36
transmembrane transporter activityGO:00228572.82
acetylcholine-activated cation-selective channel activityGO:00048896.65
passive transmembrane transporter activityGO:00228033.6
extracellular ligand-gated ion channel activityGO:00052305.42
neurotransmitter receptor activityGO:00305945.5
cation bindingGO:00431691.4
transporter activityGO:00052152.57
ion channel activityGO:00052163.71
excitatory extracellular ligand-gated ion channel activityGO:00052315.73
acetylcholine bindingGO:00421666.56
neurotransmitter bindingGO:00421656.34
cation transmembrane transporter activityGO:00083243.32
substrate-specific transmembrane transporter activityGO:00228912.9
substrate-specific transporter activityGO:00228922.72
ion transmembrane transporter activityGO:00150753.04
transmembrane signaling receptor activityGO:00048882.57
channel activityGO:00152673.6
gated channel activityGO:00228363.96
protein bindingGO:00055150.46
ligand-gated channel activityGO:00228344.8
protein dimerization activityGO:00469832.72
substrate-specific channel activityGO:00228383.67
transmembrane receptor activityGO:00996002.53
bindingGO:00054880.18