| Disease ID | Disease name | Source of annotation with CUL7 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS273750 | THREE M SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 3 | CCDC8, CUL7, OBSL1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Ubiquitin mediated proteolysis | hsa04120 | 5.63 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Unfolded Protein Response (UPR) | R-HSA-381119 | 6.56 |
| Immune System | R-HSA-168256 | 2.37 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 7.25 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 5.19 |
| IRE1alpha activates chaperones | R-HSA-381070 | 7.2 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| GO term | GO ID | GO IC |
|---|---|---|
| ubiquitin protein ligase binding | GO:0031625 | 4.17 |
| ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
| binding | GO:0005488 | 0.18 |
| enzyme binding | GO:0019899 | 2.27 |
| protein binding | GO:0005515 | 0.46 |