Disease ID | Disease name | Source of annotation with CUL7 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS273750 | THREE M SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 3 | CCDC8, CUL7, OBSL1 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Ubiquitin mediated proteolysis | hsa04120 | 5.63 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Unfolded Protein Response (UPR) | R-HSA-381119 | 6.56 |
Immune System | R-HSA-168256 | 2.37 |
XBP1(S) activates chaperone genes | R-HSA-381038 | 7.25 |
Metabolism of proteins | R-HSA-392499 | 3.41 |
Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 5.19 |
IRE1alpha activates chaperones | R-HSA-381070 | 7.2 |
Adaptive Immune System | R-HSA-1280218 | 3.19 |
GO term | GO ID | GO IC |
---|---|---|
ubiquitin protein ligase binding | GO:0031625 | 4.17 |
ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
binding | GO:0005488 | 0.18 |
enzyme binding | GO:0019899 | 2.27 |
protein binding | GO:0005515 | 0.46 |