| Disease ID | Disease name | Source of annotation with DRD5 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 606798 | BLEPHAROSPASM, BENIGN ESSENTIAL | OMIM | link to OMIM | 1 | DRD5 |
| 143465 | ATTENTION DEFICIT-HYPERACTIVITY DISORDER | OMIM | link to OMIM | 3 | DRD4, MECP2, DRD5 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Dopaminergic synapse | hsa04728 | 5.69 |
| Calcium signaling pathway | hsa04020 | 5.22 |
| Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
| cAMP signaling pathway | hsa04024 | 5.05 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Amine ligand-binding receptors | R-HSA-375280 | 7.59 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| G alpha (s) signalling events | R-HSA-418555 | 5.99 |
| Dopamine receptors | R-HSA-390651 | 10.66 |
| GO term | GO ID | GO IC |
|---|---|---|
| dopamine neurotransmitter receptor activity, coupled via Gs | GO:0001588 | 7.95 |
| G-protein coupled receptor activity | GO:0004930 | 2.95 |
| neurotransmitter receptor activity | GO:0030594 | 5.5 |
| signaling receptor activity | GO:0038023 | 2.49 |
| catecholamine binding | GO:1901338 | 6.97 |
| dopamine neurotransmitter receptor activity | GO:0004952 | 7.79 |
| molecular transducer activity | GO:0060089 | 2.32 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| dopamine binding | GO:0035240 | 7.34 |
| receptor activity | GO:0004872 | 2.32 |
| signal transducer activity | GO:0004871 | 2.28 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| binding | GO:0005488 | 0.18 |