Gene table of EIF2AK4 : eukaryotic translation initiation factor 2 alpha kinase 4

Gene-disease associations table

Disease ID	Disease name	Source of annotation with EIF2AK4	OMIM link	Number of associated genes	genes
PS265450	PULMONARY VENOOCCLUSIVE DISEASE	ClinVar, OMIM, HUMSAVAR	link to OMIM	2	EIF2AK4, BMPR2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Protein processing in endoplasmic reticulum	hsa04141	5.35
Herpes simplex infection	hsa05168	5.08
Epstein-Barr virus infection	hsa05169	4.97
Influenza A	hsa05164	5.21
Hepatitis C	hsa05160	5.68
Measles	hsa05162	5.6

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
tRNA binding	GO:0000049	5.95
nucleotide binding	GO:0000166	1.96
protein serine/threonine kinase activity	GO:0004674	3.64
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
protein kinase activity	GO:0004672	3.27
eukaryotic translation initiation factor 2alpha kinase activity	GO:0004694	8.35
ATP binding	GO:0005524	2.43
kinase activity	GO:0016301	2.93
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
adenyl ribonucleotide binding	GO:0032559	2.41
RNA binding	GO:0003723	2.36
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19