Gene table of GABBR2 : gamma-aminobutyric acid type B receptor subunit 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with GABBR2OMIM linkNumber of associated genesgenes
188890TOBACCO ADDICTION, SUSCEPTIBILITY TOClinVar, OMIM link to OMIM 4SLC6A3, CYP2A6, GABBR2, CHRNA4

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Annotation of the gene GABBR2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Morphine addictionhsa050326.15
Neuroactive ligand-receptor interactionhsa040804.58
GABAergic synapsehsa047276.24
cAMP signaling pathwayhsa040245.05
Estrogen signaling pathwayhsa049156.11
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Inwardly rectifying K+ channelsR-HSA-12960658.03
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunitsR-HSA-9972728.34
Activation of G protein gated Potassium channelsR-HSA-12960418.34
Transmission across Chemical SynapsesR-HSA-1123155.28
Signaling by GPCRR-HSA-3727902.68
Potassium ChannelsR-HSA-12960716.35
GPCR downstream signalingR-HSA-3883963.07
GABA B receptor activationR-HSA-9774447.7
GABA receptor activationR-HSA-9774437.2
Activation of GABAB receptorsR-HSA-9913657.7
G protein gated Potassium channelsR-HSA-12960598.34
G alpha (i) signalling eventsR-HSA-4185945.1
Neuronal SystemR-HSA-1123164.82
Class C/3 (Metabotropic glutamate/pheromone receptors)R-HSA-4204997.66
GPCR ligand bindingR-HSA-5007924.19
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellR-HSA-1123145.85
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
G-protein coupled receptor activityGO:00049302.95
signaling receptor activityGO:00380232.49
signal transducer activityGO:00048712.28
GABA receptor activityGO:00169176.65
molecular transducer activityGO:00600892.32
transmembrane signaling receptor activityGO:00048882.57
receptor activityGO:00048722.32
protein bindingGO:00055150.46
G-protein coupled GABA receptor activityGO:00049658.64
transmembrane receptor activityGO:00996002.53
bindingGO:00054880.18