| Disease ID | Disease name | Source of annotation with GNAI3 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS602483 | AURICULOCONDYLAR SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 3 | GNAI3, EDN1, PLCB4 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Pertussis | hsa05133 | 6.46 |
| Platelet activation | hsa04611 | 5.66 |
| cGMP-PKG signaling pathway | hsa04022 | 5.32 |
| cAMP signaling pathway | hsa04024 | 5.05 |
| Tight junction | hsa04530 | 5.53 |
| Retrograde endocannabinoid signaling | hsa04723 | 6.03 |
| Leukocyte transendothelial migration | hsa04670 | 5.74 |
| Cholinergic synapse | hsa04725 | 5.88 |
| Glutamatergic synapse | hsa04724 | 5.84 |
| GABAergic synapse | hsa04727 | 6.24 |
| Serotonergic synapse | hsa04726 | 5.84 |
| Dopaminergic synapse | hsa04728 | 5.69 |
| Chemokine signaling pathway | hsa04062 | 5.19 |
| Oxytocin signaling pathway | hsa04921 | 5.4 |
| Chagas disease (American trypanosomiasis) | hsa05142 | 5.99 |
| Toxoplasmosis | hsa05145 | 5.71 |
| Gap junction | hsa04540 | 6.24 |
| Pathways in cancer | hsa05200 | 3.98 |
| Rap1 signaling pathway | hsa04015 | 4.97 |
| Melanogenesis | hsa04916 | 5.97 |
| Progesterone-mediated oocyte maturation | hsa04914 | 6.18 |
| Estrogen signaling pathway | hsa04915 | 6.11 |
| Circadian entrainment | hsa04713 | 6.11 |
| Long-term depression | hsa04730 | 6.74 |
| Gastric acid secretion | hsa04971 | 6.48 |
| Morphine addiction | hsa05032 | 6.15 |
| Cocaine addiction | hsa05030 | 7.07 |
| Alcoholism | hsa05034 | 5.59 |
| Axon guidance | hsa04360 | 5.63 |
| Adrenergic signaling in cardiomyocytes | hsa04261 | 5.44 |
| Parkinson's disease | hsa05012 | 5.59 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| G alpha (i) signalling events | R-HSA-418594 | 5.1 |
| G alpha (z) signalling events | R-HSA-418597 | 7.46 |
| G alpha (s) signalling events | R-HSA-418555 | 5.99 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 9.18 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
| GABA receptor activation | R-HSA-977443 | 7.2 |
| GABA B receptor activation | R-HSA-977444 | 7.7 |
| Neuronal System | R-HSA-112316 | 4.82 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | R-HSA-112314 | 5.85 |
| Transmission across Chemical Synapses | R-HSA-112315 | 5.28 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 8.52 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Signal amplification | R-HSA-392518 | 7.98 |
| Activation of GABAB receptors | R-HSA-991365 | 7.7 |
| PLC beta mediated events | R-HSA-112043 | 7.52 |
| G-protein mediated events | R-HSA-112040 | 7.49 |
| Opioid Signalling | R-HSA-111885 | 6.64 |
| G-protein activation | R-HSA-202040 | 8.18 |
| Inhibition of adenylate cyclase pathway | R-HSA-997269 | 9.18 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| purine ribonucleoside triphosphate binding | GO:0035639 | 2.22 |
| GTPase activating protein binding | GO:0032794 | 7.1 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| G-protein coupled receptor binding | GO:0001664 | 4.18 |
| nucleotide binding | GO:0000166 | 1.96 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |
| nucleoside binding | GO:0001882 | 2.21 |
| cation binding | GO:0043169 | 1.4 |
| pyrophosphatase activity | GO:0016462 | 3.04 |
| ion binding | GO:0043167 | 1.36 |
| guanyl ribonucleotide binding | GO:0032561 | 3.73 |
| purine nucleoside binding | GO:0001883 | 2.22 |
| ribonucleoside binding | GO:0032549 | 2.22 |
| protein complex binding | GO:0032403 | 3.09 |
| G-protein coupled serotonin receptor binding | GO:0031821 | 7.79 |
| metal ion binding | GO:0046872 | 1.41 |
| GTP binding | GO:0005525 | 3.78 |
| hydrolase activity | GO:0016787 | 1.9 |
| G-protein beta/gamma-subunit complex binding | GO:0031683 | 6.65 |
| GTPase activity | GO:0003924 | 4.31 |
| nucleoside-triphosphatase activity | GO:0017111 | 3.09 |
| small molecule binding | GO:0036094 | 1.89 |
| catalytic activity | GO:0003824 | 1.05 |
| protein domain specific binding | GO:0019904 | 3.32 |
| purine nucleotide binding | GO:0017076 | 2.19 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | GO:0016818 | 3.03 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| hydrolase activity, acting on acid anhydrides | GO:0016817 | 3.03 |
| guanyl nucleotide binding | GO:0019001 | 3.73 |
| GDP binding | GO:0019003 | 5.81 |
| protein binding | GO:0005515 | 0.46 |
| purine ribonucleotide binding | GO:0032555 | 2.2 |
| receptor binding | GO:0005102 | 2.43 |
| purine ribonucleoside binding | GO:0032550 | 2.22 |
| ribonucleotide binding | GO:0032553 | 2.19 |