Gene table of LTC4S : leukotriene C4 synthase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with LTC4S	OMIM link	Number of associated genes	genes
614037	LEUKOTRIENE C4 SYNTHASE DEFICIENCY	OMIM	link to OMIM	1	LTC4S

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Arachidonic acid metabolism	hsa00590	6.79
Metabolic pathways	hsa01100	2.49

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Synthesis of Lipoxins (LX)	R-HSA-2142700	10.4
Metabolism	R-HSA-1430728	2.34
Synthesis of 5-eicosatetraenoic acids	R-HSA-2142688	10.4
Arachidonic acid metabolism	R-HSA-2142753	7.34
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	8.59

Associated GO terms for Molecular function

GO term	GO ID	GO IC
binding	GO:0005488	0.18
enzyme activator activity	GO:0008047	3.56
molecular function regulator	GO:0098772	2.51
oxidoreductase activity	GO:0016491	3.12
sulfur compound binding	GO:1901681	4.32
glutathione transferase activity	GO:0004364	6.18
peptide binding	GO:0042277	4.22
lyase activity	GO:0016829	4.53
leukotriene-C4 synthase activity	GO:0004464	8.64
transferase activity, transferring alkyl or aryl (other than methyl) groups	GO:0016765	5.58
transferase activity	GO:0016740	1.95
oxidoreductase activity, acting on peroxide as acceptor	GO:0016684	6.0
oligopeptide binding	GO:1900750	7.25
enzyme regulator activity	GO:0030234	2.85
amide binding	GO:0033218	4.14
antioxidant activity	GO:0016209	5.49
lipid binding	GO:0008289	3.26
catalytic activity	GO:0003824	1.05
carbon-sulfur lyase activity	GO:0016846	7.54
modified amino acid binding	GO:0072341	5.56
protein binding	GO:0005515	0.46
protein dimerization activity	GO:0046983	2.72
protein heterodimerization activity	GO:0046982	3.64
peroxidase activity	GO:0004601	6.05
glutathione peroxidase activity	GO:0004602	6.85
glutathione binding	GO:0043295	7.34