Disease ID | Disease name | Source of annotation with MAOA | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
300615 | BRUNNER SYNDROME | ClinVar, OMIM | link to OMIM | 1 | MAOA |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Drug metabolism - cytochrome P450 | hsa00982 | 6.6 |
Arginine and proline metabolism | hsa00330 | 6.84 |
Metabolic pathways | hsa01100 | 2.49 |
Cocaine addiction | hsa05030 | 7.07 |
Amphetamine addiction | hsa05031 | 6.62 |
Phenylalanine metabolism | hsa00360 | 8.6 |
Alcoholism | hsa05034 | 5.59 |
Serotonergic synapse | hsa04726 | 5.84 |
Glycine, serine and threonine metabolism | hsa00260 | 7.45 |
Dopaminergic synapse | hsa04728 | 5.69 |
Tryptophan metabolism | hsa00380 | 7.34 |
Tyrosine metabolism | hsa00350 | 7.64 |
Histidine metabolism | hsa00340 | 8.24 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Transmission across Chemical Synapses | R-HSA-112315 | 5.28 |
Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 8.81 |
Metabolism of serotonin | R-HSA-380612 | 11.98 |
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB | R-HSA-141333 | 11.98 |
Biological oxidations | R-HSA-211859 | 5.55 |
Enzymatic degradation of dopamine by COMT | R-HSA-379397 | 11.98 |
Enzymatic degradation of Dopamine by monoamine oxidase | R-HSA-379398 | 11.98 |
Dopamine clearance from the synaptic cleft | R-HSA-379401 | 11.4 |
Diseases of metabolism | R-HSA-5668914 | 6.57 |
Defective MAOA causes Brunner syndrome (BRUNS) | R-HSA-5579012 | 12.98 |
Phase 1 - Functionalization of compounds | R-HSA-211945 | 6.7 |
Serotonin clearance from the synaptic cleft | R-HSA-380615 | 11.98 |
Metabolism | R-HSA-1430728 | 2.34 |
Disease | R-HSA-1643685 | 3.33 |
Neuronal System | R-HSA-112316 | 4.82 |
Amine Oxidase reactions | R-HSA-140179 | 10.98 |
Neurotransmitter Release Cycle | R-HSA-112310 | 7.34 |
Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 7.85 |
Neurotransmitter Clearance In The Synaptic Cleft | R-HSA-112311 | 9.98 |
GO term | GO ID | GO IC |
---|---|---|
coenzyme binding | GO:0050662 | 4.53 |
serotonin binding | GO:0051378 | 7.54 |
flavin adenine dinucleotide binding | GO:0050660 | 5.41 |
oxidoreductase activity, acting on the CH-NH2 group of donors | GO:0016638 | 6.74 |
organic cyclic compound binding | GO:0097159 | 1.05 |
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | GO:0016641 | 7.03 |
primary amine oxidase activity | GO:0008131 | 7.95 |
small molecule binding | GO:0036094 | 1.89 |
catalytic activity | GO:0003824 | 1.05 |
cofactor binding | GO:0048037 | 4.16 |
binding | GO:0005488 | 0.18 |
amine binding | GO:0043176 | 7.34 |
nucleotide binding | GO:0000166 | 1.96 |
heterocyclic compound binding | GO:1901363 | 1.06 |
nucleoside phosphate binding | GO:1901265 | 1.96 |
oxidoreductase activity | GO:0016491 | 3.12 |