Gene table of MEF2A : myocyte enhancer factor 2A

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MEF2A	OMIM link	Number of associated genes	genes
608320	CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 1	OMIM	link to OMIM	1	MEF2A

Download the gene annotation in CSV format

Annotation of the gene MEF2A

Associated genes in ENSEMBL

ENSG00000068305

Associated proteins - SwissProt Accession ID

Q02078

Associated PDB IDs

Cytogenetic Band

15q26.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
cGMP-PKG signaling pathway	hsa04022	5.32

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
TRIF-mediated TLR3/TLR4 signaling	R-HSA-937061	6.47
ERK/MAPK targets	R-HSA-198753	8.59
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	6.51
Immune System	R-HSA-168256	2.37
MyD88 cascade initiated on plasma membrane	R-HSA-975871	6.73
CDO in myogenesis	R-HSA-375170	8.12
Developmental Biology	R-HSA-1266738	3.48
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	8.08
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	6.73
Signalling by NGF	R-HSA-166520	4.23
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	6.47
Toll-Like Receptors Cascades	R-HSA-168898	5.91
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	8.4
MyD88-independent TLR3/TLR4 cascade	R-HSA-166166	6.47
Myogenesis	R-HSA-525793	8.12
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	6.56
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	6.11
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	6.68
Innate Immune System	R-HSA-168249	3.17
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	6.51
NGF signalling via TRKA from the plasma membrane	R-HSA-187037	4.51
MAP kinase activation in TLR cascade	R-HSA-450294	7.28
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	6.72
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	6.73
MyD88 dependent cascade initiated on endosome	R-HSA-975155	6.68
MyD88:Mal cascade initiated on plasma membrane	R-HSA-166058	6.56
Activated TLR4 signalling	R-HSA-166054	6.27
Signal Transduction	R-HSA-162582	1.78
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	6.62

Associated GO terms for Molecular function

GO term	GO ID	GO IC
SMAD binding	GO:0046332	5.45
activating transcription factor binding	GO:0033613	5.68
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription factor activity, RNA polymerase II transcription factor binding	GO:0001076	4.84
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
transcriptional repressor activity, RNA polymerase II activating transcription factor binding	GO:0098811	5.77
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
transcriptional repressor activity, RNA polymerase II transcription factor binding	GO:0001191	5.28
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
histone deacetylase binding	GO:0042826	5.08
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
transcription regulatory region DNA binding	GO:0044212	3.03
transcription factor binding	GO:0008134	3.46
regulatory region nucleic acid binding	GO:0001067	3.03
histone acetyltransferase binding	GO:0035035	6.41
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
transcriptional activator activity, RNA polymerase II transcription factor binding	GO:0001190	5.77
enzyme binding	GO:0019899	2.27
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
RNA polymerase II transcription factor binding	GO:0001085	5.08
RNA polymerase II transcription cofactor activity	GO:0001104	5.22
protein heterodimerization activity	GO:0046982	3.64
RNA polymerase II transcription coactivator activity	GO:0001105	6.15
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	GO:0003705	5.23
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
protein dimerization activity	GO:0046983	2.72
chromatin binding	GO:0003682	3.64
nucleic acid binding transcription factor activity	GO:0001071	2.65