Gene table of MMP14 : matrix metallopeptidase 14

Gene-disease associations table

Disease IDDisease nameSource of annotation with MMP14OMIM linkNumber of associated genesgenes
277950WINCHESTER SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 1MMP14

Download the gene annotation in CSV format

Annotation of the gene MMP14

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
TNF signaling pathwayhsa046685.96
GnRH signaling pathwayhsa049126.18
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Activation of Matrix MetalloproteinasesR-HSA-15923898.03
Extracellular matrix organizationR-HSA-14742444.91
Degradation of the extracellular matrixR-HSA-14742286.11
Collagen degradationR-HSA-14424907.03
Associated GO terms for Molecular function
GO termGO IDGO IC
bindingGO:00054880.18
serine-type endopeptidase activityGO:00042524.4
endopeptidase activityGO:00041753.63
integrin bindingGO:00051785.07
macromolecular complex bindingGO:00448772.61
zinc ion bindingGO:00082702.66
peptidase activityGO:00082333.23
molecular function regulatorGO:00987722.51
metallopeptidase activityGO:00082374.5
serine-type peptidase activityGO:00082364.27
cation bindingGO:00431691.4
transition metal ion bindingGO:00469142.48
ion bindingGO:00431671.36
calcium ion bindingGO:00055093.17
protein complex bindingGO:00324033.09
metal ion bindingGO:00468721.41
hydrolase activityGO:00167871.9
metalloendopeptidase activityGO:00042225.02
serine hydrolase activityGO:00171714.26
enzyme regulator activityGO:00302342.85
peptidase regulator activityGO:00611344.37
catalytic activityGO:00038241.05
cell adhesion molecule bindingGO:00508394.5
peptidase activity, acting on L-amino acid peptidesGO:00700113.26
protein bindingGO:00055150.46
peptidase activator activityGO:00165046.13
receptor bindingGO:00051022.43
enzyme activator activityGO:00080473.56