Disease ID | Disease name | Source of annotation with PRSS1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
614044 | TRYPSINOGEN DEFICIENCY | OMIM | link to OMIM | 1 | PRSS1 |
167800 | PANCREATITIS, HEREDITARY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 5 | PRSS2, SPINK1, CTRC, PRSS1, CFTR |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Influenza A | hsa05164 | 5.21 |
Protein digestion and absorption | hsa04974 | 6.2 |
Pancreatic secretion | hsa04972 | 6.07 |
Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Metabolism of vitamins and cofactors | R-HSA-196854 | 6.54 |
Degradation of the extracellular matrix | R-HSA-1474228 | 6.11 |
Activation of Matrix Metalloproteinases | R-HSA-1592389 | 8.03 |
Extracellular matrix organization | R-HSA-1474244 | 4.91 |
Metabolism | R-HSA-1430728 | 2.34 |
Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 6.54 |
Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 8.73 |
GO term | GO ID | GO IC |
---|---|---|
hydrolase activity | GO:0016787 | 1.9 |
endopeptidase activity | GO:0004175 | 3.63 |
serine-type endopeptidase activity | GO:0004252 | 4.4 |
serine hydrolase activity | GO:0017171 | 4.26 |
cation binding | GO:0043169 | 1.4 |
ion binding | GO:0043167 | 1.36 |
catalytic activity | GO:0003824 | 1.05 |
peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
binding | GO:0005488 | 0.18 |
peptidase activity | GO:0008233 | 3.23 |
metal ion binding | GO:0046872 | 1.41 |
serine-type peptidase activity | GO:0008236 | 4.27 |