Gene table of SLC11A2 : solute carrier family 11 member 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC11A2	OMIM link	Number of associated genes	genes
PS206100	ANEMIA, HYPOCHROMIC MICROCYTIC, WITH IRON OVERLOAD	ClinVar, OMIM, HUMSAVAR	link to OMIM	2	SLC11A2, STEAP3

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Annotation of the gene SLC11A2

Associated genes in ENSEMBL

ENSG00000110911

Associated proteins - SwissProt Accession ID

P49281

Associated PDB IDs

Cytogenetic Band

12q13.12

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Mineral absorption	hsa04978	7.09
Lysosome	hsa04142	5.78

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
SLC-mediated transmembrane transport	R-HSA-425407	4.95
Metal ion SLC transporters	R-HSA-425410	8.34
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	R-HSA-425366	6.34
Iron uptake and transport	R-HSA-917937	7.56
Transmembrane transport of small molecules	R-HSA-382551	3.79

Associated GO terms for Molecular function

GO term	GO ID	GO IC
metal ion binding	GO:0046872	1.41
binding	GO:0005488	0.18
ion binding	GO:0043167	1.36
protein transporter activity	GO:0008565	5.17
calcium ion transmembrane transporter activity	GO:0015085	4.89
cadmium ion transmembrane transporter activity	GO:0015086	9.74
cobalt ion transmembrane transporter activity	GO:0015087	9.74
transition metal ion binding	GO:0046914	2.48
transition metal ion transmembrane transporter activity	GO:0046915	6.05
transmembrane transporter activity	GO:0022857	2.82
divalent inorganic cation transmembrane transporter activity	GO:0072509	4.62
primary active transmembrane transporter activity	GO:0015399	4.98
vanadium ion transmembrane transporter activity	GO:0015100	9.74
cadmium ion binding	GO:0046870	8.13
copper ion transmembrane transporter activity	GO:0005375	7.95
lead ion transmembrane transporter activity	GO:0015094	9.74
active transmembrane transporter activity	GO:0022804	3.85
solute:proton symporter activity	GO:0015295	6.48
solute:cation symporter activity	GO:0015294	5.15
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	GO:0015450	7.54
secondary active transmembrane transporter activity	GO:0015291	4.29
manganese ion transmembrane transporter activity	GO:0005384	7.95
symporter activity	GO:0015293	4.78
cation binding	GO:0043169	1.4
transporter activity	GO:0005215	2.57
ferrous iron uptake transmembrane transporter activity	GO:0015639	9.74
cation transmembrane transporter activity	GO:0008324	3.32
protein transmembrane transporter activity	GO:0008320	6.79
nickel cation transmembrane transporter activity	GO:0015099	9.74
ferrous iron transmembrane transporter activity	GO:0015093	8.64
ferric iron transmembrane transporter activity	GO:0015091	8.64
metal ion transmembrane transporter activity	GO:0046873	3.71
trivalent inorganic cation transmembrane transporter activity	GO:0072510	8.64
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
macromolecule transmembrane transporter activity	GO:0022884	6.65
chromium ion transmembrane transporter activity	GO:0070835	9.74
hydrogen ion transmembrane transporter activity	GO:0015078	5.01
ion transmembrane transporter activity	GO:0015075	3.04
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
iron ion transmembrane transporter activity	GO:0005381	7.66
transferrin transmembrane transporter activity	GO:0033570	9.05
protein binding	GO:0005515	0.46
zinc ion transmembrane transporter activity	GO:0005385	6.56
P-P-bond-hydrolysis-driven transmembrane transporter activity	GO:0015405	4.98