Gene table of SLC5A5 : solute carrier family 5 member 5

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC5A5	OMIM link	Number of associated genes	genes
274400	THYROID DYSHORMONOGENESIS 1	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	SLC5A5

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Thyroid hormone synthesis	hsa04918	6.56

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Organic anion transporters	R-HSA-428643	9.98
Metabolism of amino acids and derivatives	R-HSA-71291	5.4
Transmembrane transport of small molecules	R-HSA-382551	3.79
Transport of inorganic cations/anions and amino acids/oligopeptides	R-HSA-425393	6.41
Amine-derived hormones	R-HSA-209776	8.98
Metabolism	R-HSA-1430728	2.34
SLC-mediated transmembrane transport	R-HSA-425407	4.95
Thyroxine biosynthesis	R-HSA-209968	9.98

Associated GO terms for Molecular function

GO term	GO ID	GO IC
sodium:iodide symporter activity	GO:0008507	9.74
sodium ion transmembrane transporter activity	GO:0015081	4.83
anion transmembrane transporter activity	GO:0008509	4.43
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
monovalent anion:sodium symporter activity	GO:0015373	9.74
solute:sodium symporter activity	GO:0015370	5.83
inorganic anion transmembrane transporter activity	GO:0015103	4.87
metal ion transmembrane transporter activity	GO:0046873	3.71
active transmembrane transporter activity	GO:0022804	3.85
solute:cation symporter activity	GO:0015294	5.15
anion:cation symporter activity	GO:0015296	6.15
secondary active transmembrane transporter activity	GO:0015291	4.29
symporter activity	GO:0015293	4.78
transporter activity	GO:0005215	2.57
cation transmembrane transporter activity	GO:0008324	3.32
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
ion transmembrane transporter activity	GO:0015075	3.04
transmembrane transporter activity	GO:0022857	2.82
active ion transmembrane transporter activity	GO:0022853	5.06
iodide transmembrane transporter activity	GO:0015111	8.64