| Disease ID | Disease name | Source of annotation with SYT2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS601462 | MYASTHENIC SYNDROME, CONGENITAL | ClinVar, OMIM, HUMSAVAR | link to OMIM | 23 | LRP4, CHRNE, DOK7, CHRNB1, CHAT, COX10, COLQ, COL13A1, DPAGT1, ALG14, MUSK, AGRN, SNAP25, SURF1, GFPT1, CHRNA1, RAPSN, CHRND, SCN4A, TACO1, SYT2, COX15, ALG2 |
Download the gene annotation in CSV format
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 8.28 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.66 |
| Disease | R-HSA-1643685 | 3.33 |
| Toxicity of botulinum toxin type B (BoNT/B) | R-HSA-5250958 | 11.4 |
| GO term | GO ID | GO IC |
|---|---|---|
| inositol 1,3,4,5 tetrakisphosphate binding | GO:0043533 | 8.35 |
| cation binding | GO:0043169 | 1.4 |
| alcohol binding | GO:0043178 | 5.53 |
| SNARE binding | GO:0000149 | 4.87 |
| phospholipid binding | GO:0005543 | 3.91 |
| calcium-dependent phospholipid binding | GO:0005544 | 5.71 |
| lipid binding | GO:0008289 | 3.26 |
| ion binding | GO:0043167 | 1.36 |
| small molecule binding | GO:0036094 | 1.89 |
| syntaxin binding | GO:0019905 | 5.19 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| clathrin binding | GO:0030276 | 5.55 |
| metal ion binding | GO:0046872 | 1.41 |
| calcium ion binding | GO:0005509 | 3.17 |