Disease table of EXFOLIATION SYNDROME OMIM ID: 177650

Gene-disease associations table

GeneAssociated with EXFOLIATION SYNDROME inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
LOXL1OMIMHGNC link15q24.11177650
LTBP2ClinVarHGNC link14q24.37154700, 251750, 129600, PS277600, 177650, 613086, 137760

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Elastic fibre formationR-HSA-15669487.492LOXL1, LTBP2
Extracellular matrix organizationR-HSA-14742444.912LOXL1, LTBP2

NET-GE enrichment

Term New enriched termICP valueGenes
Elastic fibre formation (R-HSA-1566948) -7.490.0LOXL1, LTBP2
Extracellular matrix organization (R-HSA-1474244) -4.910.023LOXL1, LTBP2
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cation binding (GO:0043169) 1.42LOXL1, LTBP2
metal ion binding (GO:0046872) 1.412LOXL1, LTBP2
binding (GO:0005488) 0.182LOXL1, LTBP2
ion binding (GO:0043167) 1.362LOXL1, LTBP2
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cellular process (GO:0009987) 0.262LOXL1, LTBP2
cellular component organization (GO:0016043) 1.242LOXL1, LTBP2
extracellular matrix organization (GO:0030198) 4.012LOXL1, LTBP2
single-organism cellular process (GO:0044763) 0.652LOXL1, LTBP2
single-organism process (GO:0044699) 0.482LOXL1, LTBP2
extracellular structure organization (GO:0043062) 4.02LOXL1, LTBP2
cellular component organization or biogenesis (GO:0071840) 1.222LOXL1, LTBP2
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
extracellular space (GO:0005615) 2.632LOXL1, LTBP2
extracellular region part (GO:0044421) 1.572LOXL1, LTBP2
proteinaceous extracellular matrix (GO:0005578) 4.012LOXL1, LTBP2
cell part (GO:0044464) 0.112LOXL1, LTBP2
membrane-bounded vesicle (GO:0031988) 1.712LOXL1, LTBP2
extracellular region (GO:0005576) 2.182LOXL1, LTBP2
extracellular matrix (GO:0031012) 3.812LOXL1, LTBP2
membrane-bounded organelle (GO:0043227) 0.472LOXL1, LTBP2
organelle (GO:0043226) 0.42LOXL1, LTBP2
vesicle (GO:0031982) 1.642LOXL1, LTBP2

NET-GE enrichment

Term New enriched termICP valueGenes
extracellular space (GO:0005615) -2.630.047LOXL1, LTBP2
proteinaceous extracellular matrix (GO:0005578) -4.010.007LOXL1, LTBP2
extracellular matrix (GO:0031012) -3.810.003LOXL1, LTBP2