| Disease ID | Disease name | Source of annotation with AGXT | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS259900 | HYPEROXALURIA, PRIMARY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 3 | HOGA1, AGXT, GRHPR |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Carbon metabolism | hsa01200 | 6.03 |
| Metabolic pathways | hsa01100 | 2.49 |
| Glyoxylate and dicarboxylate metabolism | hsa00630 | 8.07 |
| Alanine, aspartate and glutamate metabolism | hsa00250 | 7.64 |
| Peroxisome | hsa04146 | 6.34 |
| Glycine, serine and threonine metabolism | hsa00260 | 7.45 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Glyoxylate metabolism | R-HSA-389661 | 10.66 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 5.4 |
| GO term | GO ID | GO IC |
|---|---|---|
| anion binding | GO:0043168 | 4.17 |
| GO:0008453 | 9.05 | |
| catalytic activity | GO:0003824 | 1.05 |
| protein self-association | GO:0043621 | 5.93 |
| protein dimerization activity | GO:0046983 | 2.72 |
| carboxylic acid binding | GO:0031406 | 4.64 |
| ion binding | GO:0043167 | 1.36 |
| transaminase activity | GO:0008483 | 6.74 |
| transferase activity | GO:0016740 | 1.95 |
| GO:0004760 | 9.74 | |
| cofactor binding | GO:0048037 | 4.16 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| protein homodimerization activity | GO:0042803 | 3.16 |
| amino acid binding | GO:0016597 | 5.71 |
| transferase activity, transferring nitrogenous groups | GO:0016769 | 6.65 |
| identical protein binding | GO:0042802 | 2.63 |
| pyridoxal phosphate binding | GO:0030170 | 5.83 |