Gene table of ALG1 : ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase

Gene-disease associations table

Disease IDDisease nameSource of annotation with ALG1OMIM linkNumber of associated genesgenes
PS212065CONGENITAL DISORDERS OF GLYCOSYLATION, TYPE IClinVar, OMIM, HUMSAVAR link to OMIM 25ALG2, ALG1, ALG13, ALG3, CAD, STT3A, SRD5A3, ALG12, ALG8, DPAGT1, DDOST, ALG6, MPI, PMM2, STT3B, DOLK, MPDU1, RFT1, PGM1, ALG9, DPM1, DPM3, ALG11, DPM2, SSR4

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Annotation of the gene ALG1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
N-Glycan biosynthesishsa005107.07
Metabolic pathwayshsa011002.49
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Defective ALG1 causes ALG1-CDG (CDG-1k)R-HSA-454938012.98
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinR-HSA-4461936.92
Metabolism of proteinsR-HSA-3924993.41
Asparagine N-linked glycosylationR-HSA-4462036.1
Diseases of glycosylationR-HSA-37818656.89
Post-translational protein modificationR-HSA-5975924.54
Diseases associated with N-glycosylation of proteinsR-HSA-37818608.89
DiseaseR-HSA-16436853.33
Associated GO terms for Molecular function
GO termGO IDGO IC
transferase activity, transferring glycosyl groupsGO:00167574.08
catalytic activityGO:00038241.05
transferase activityGO:00167401.95
GO:00191879.74
transferase activity, transferring hexosyl groupsGO:00167584.43
GO:00045789.74
mannosyltransferase activityGO:00000306.52