Disease table of CONGENITAL DISORDERS OF GLYCOSYLATION, TYPE I OMIM ID: PS212065

Gene-disease associations table

GeneAssociated with CONGENITAL DISORDERS OF GLYCOSYLATION, TYPE I inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
DOLKClinVar, OMIM, HUMSAVARHGNC link9q34.111PS212065
ALG8ClinVar, OMIM, HUMSAVARHGNC link11q14.11PS212065
ALG9ClinVar, OMIM, HUMSAVARHGNC link11q23.11PS212065
ALG2ClinVar, OMIMHGNC link9q22.332PS212065, PS601462
ALG3ClinVar, OMIM, HUMSAVARHGNC link3q27.11PS212065
ALG1ClinVar, OMIM, HUMSAVARHGNC link16p13.31PS212065
ALG6ClinVar, OMIM, HUMSAVARHGNC link1p31.31PS212065
DDOSTClinVar, OMIM, HUMSAVARHGNC link1p36.121PS212065
MPDU1ClinVar, OMIM, HUMSAVARHGNC link17p13.11PS212065
STT3BClinVar, OMIMHGNC link3p231PS212065
PMM2ClinVar, OMIM, HUMSAVARHGNC link16p13.21PS212065
ALG12ClinVar, OMIM, HUMSAVARHGNC link22q13.331PS212065
CADClinVar, OMIM, HUMSAVARHGNC link2p23.31PS212065
SRD5A3ClinVar, OMIMHGNC link4q122PS212065, 612713
DPM3ClinVar, OMIM, HUMSAVARHGNC link1q221PS212065
DPM2ClinVar, OMIM, HUMSAVARHGNC link9q34.111PS212065
DPM1ClinVar, OMIM, HUMSAVARHGNC link20q13.131PS212065
DPAGT1ClinVar, OMIM, HUMSAVARHGNC link11q23.32PS212065, PS601462
PGM1ClinVar, OMIM, HUMSAVARHGNC link1p31.31PS212065
ALG11ClinVar, OMIM, HUMSAVARHGNC link13q14.31PS212065
STT3AClinVar, OMIM, HUMSAVARHGNC link11q24.21PS212065
ALG13ClinVar, OMIM, HUMSAVARHGNC linkXq232PS212065, PS308350
MPIClinVar, OMIM, HUMSAVARHGNC link15q24.11PS212065
SSR4OMIMHGNC linkXq281PS212065
RFT1ClinVar, OMIM, HUMSAVARHGNC link3p21.11PS212065

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By sub-band
Shared sub_bandNumber of genes associated with the diseaseGenes associated with the disease
1p31.32ALG6, PGM1
9q34.112DOLK, DPM2
By band
Shared bandNumber of genes associated with the diseaseGenes associated with the disease
9q342DOLK, DPM2
16p132ALG1, PMM2
11q232ALG9, DPAGT1
1p312ALG6, PGM1
By region
Shared regionNumber of genes associated with the diseaseGenes associated with the disease
16p12ALG1, PMM2
3p22RFT1, STT3B
11q23ALG9, STT3A, DPAGT1
1p33ALG6, PGM1, DDOST
Xq22SSR4, ALG13
9q32DOLK, DPM2
By arm
Shared armNumber of genes associated with the diseaseGenes associated with the disease
1p3ALG6, PGM1, DDOST
3p2RFT1, STT3B
11q4ALG8, ALG9, DPAGT1, STT3A
9q3DOLK, ALG2, DPM2
Xq2SSR4, ALG13
16p2ALG1, PMM2
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
114ALG8, ALG9, DPAGT1, STT3A
162ALG1, PMM2
14ALG6, DPM3, DDOST, PGM1
33ALG3, RFT1, STT3B
93DOLK, ALG2, DPM2
X2SSR4, ALG13
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
CADYES3MYC, HDAC2, SMARCA40
SRD5A3YES1AR0
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
DOLKALG3No2CREB3, ERGIC3
ALG8ALG3No1GPR52
ALG8ALG1No1NXF1
ALG8DDOSTNo1NXF1
ALG8MPDU1No1NXF1
ALG8ALG11No1TSPAN5
ALG8STT3ANo1ATP2A2
ALG8RFT1No2GPR52, TSPAN5
ALG9ALG3No2TCTN3, TCTN2
ALG9ALG6No2TCTN3, ZACN
ALG9DDOSTNo2TCTN3, TCTN2
ALG9STT3BNo4TCTN3, TMEM216, CORO1C, TCTN2
ALG9RFT1No3TCTN3, TCTN2, ZACN
ALG2DDOSTNo1HSP90AA1
ALG2MPINo1SRI
ALG2SSR4No1HSP90AA1
ALG3ALG6No2TCTN3, LPAR1
ALG3DDOSTNo2TCTN3, TCTN2
ALG3STT3BNo2TCTN3, TCTN2
ALG3RFT1No3TCTN3, GPR52, TCTN2
ALG1DDOSTNo3NXF1, FBXO6, MOV10
ALG1MPDU1No2NXF1, MOV10
ALG1STT3BNo1FBXO6
ALG1CADNo2RPS6KB2, FBXO6
ALG1DPM1No1FBXO6
ALG1STT3ANo1FBXO6
ALG1SSR4No1FBXO6
ALG6DDOSTNo1TCTN3
ALG6STT3BNo1TCTN3
ALG6RFT1No3TCTN3, TMEM171, ZACN
DDOSTMPDU1No2NXF1, MOV10
DDOSTSTT3BYes12TMEM173, RPN1, TCTN2, TCTN3, UNC93B1, TCTN1, RPN2, MAGT1, FBXO6, NTRK1, AUP1, KRTCAP2
DDOSTCADNo10STAU1, CLTC, UQCRC2, MCM2, SLC25A3, FBXO6, NTRK1, HDAC5, ATP1A1, CUL7
DDOSTDPM1No5NTRK1, MCM2, HUWE1, FBXO6, CLN3
DDOSTPGM1No1NTRK1
DDOSTSTT3ANo6TMEM173, KTN1, FBXO6, NTRK1, KRTCAP2, UNC93B1
DDOSTSSR4Yes19HSP90AA1, UQCRC2, RPN1, CLN3, FBXO6, MAGT1, RPN2, ATP5C1, HUWE1, COX2, SLC25A3, VAPB, TECR, SUZ12, HSP90AB1, COX4I1, ILF2, MCM2, SSR1
DDOSTRFT1No3TCTN3, VAPB, TCTN2
STT3BCADNo2NTRK1, FBXO6
STT3BDPM1No2NTRK1, FBXO6
STT3BPGM1No1NTRK1
STT3BSTT3ANo8TMEM173, UNC93B1, NTRK1, MAD2L1, FBXO6, TMED2, KRTCAP2, OST4
STT3BSSR4No5MAGT1, RPN1, DDOST, FBXO6, RPN2
STT3BRFT1No3TCTN3, TMED2, TCTN2
CADDPM1No5NTRK1, ILK, MCM2, FBXO6, TUBG1
CADDPAGT1No1CUL3
CADPGM1No1NTRK1
CADSTT3ANo2NTRK1, FBXO6
CADSSR4No11UQCRC2, NOS2, OTUB1, CDK2, ILK, MCM2, TUBA1C, SLC25A3, FBXO6, CUL3, KSR1
CADRFT1No1NEDD4
DPM3DPM2No1DPM1
DPM3DPM1Yes0
DPM3PGM1No1TINF2
DPM2DPM1Yes0
DPM1PGM1No1NTRK1
DPM1STT3ANo3NTRK1, FBXO6, EGFR
DPM1SSR4No9FBXO6, ILK, MCM2, HUWE1, CLN3, AATK, EGFR, BMI1, MYC
DPAGT1SSR4No1CUL3
PGM1STT3ANo1NTRK1
PGM1MPINo2SOD1, APP
PGM1SSR4No1SOD1
ALG11RFT1No1TSPAN5
STT3ASSR4No2FBXO6, EGFR
STT3ARFT1No1TMED2
MPISSR4No1SOD1
SSR4RFT1No1VAPB

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
ALG8ALG3No-1UBC
ALG8ALG1No-1UBC
ALG8DDOSTNo-1UBC
ALG8MPDU1No-1UBC
ALG8STT3BNo-1UBC
ALG8PMM2No-1UBC
ALG8CADNo-1UBC
ALG8DPM1No-1UBC
ALG8DPAGT1No-1UBC
ALG8PGM1No-1UBC
ALG8STT3ANo-1UBC
ALG3ALG1No-1UBC
ALG3DDOSTNo-1UBC
ALG3MPDU1No-1UBC
ALG3STT3BNo-1UBC
ALG3PMM2No-1UBC
ALG3CADNo-1UBC
ALG3DPM1No-1UBC
ALG3DPAGT1No-1UBC
ALG3PGM1No-1UBC
ALG3STT3ANo-1UBC
ALG1DDOSTNo-1UBC
ALG1MPDU1No-1UBC
ALG1STT3BNo-1UBC
ALG1PMM2No-1UBC
ALG1CADNo-1UBC
ALG1DPM1No-1UBC
ALG1DPAGT1No-1UBC
ALG1PGM1No-1UBC
ALG1STT3ANo-1UBC
DDOSTMPDU1No-1UBC
DDOSTSTT3BYesbinding9RPN1, SEC61B, TUSC3, STT3A, RPN2, OSTC, DAD1, UBC, KRTCAP2
DDOSTPMM2No-1UBC
DDOSTCADNo-6RPS27A, UBA52, RPSA, UBC, UBB, RPL7
DDOSTDPM1No-2UBC, UBB
DDOSTDPAGT1No-1UBC
DDOSTPGM1No-1UBC
DDOSTSTT3AYesbinding9RPN1, SEC61B, TUSC3, RPN2, STT3B, OSTC, DAD1, UBC, KRTCAP2
MPDU1STT3BNo-1UBC
MPDU1PMM2No-1UBC
MPDU1CADNo-1UBC
MPDU1DPM1No-1UBC
MPDU1DPAGT1No-1UBC
MPDU1PGM1No-1UBC
MPDU1STT3ANo-1UBC
STT3BPMM2No-1UBC
STT3BCADNo-1UBC
STT3BDPM1No-1UBC
STT3BDPAGT1No-1UBC
STT3BPGM1No-1UBC
STT3BSTT3AYesbinding9RPN1, DDOST, SEC61B, TUSC3, RPN2, OSTC, DAD1, UBC, KRTCAP2
PMM2CADNo-1UBC
PMM2DPM1No-1UBC
PMM2DPAGT1No-1UBC
PMM2PGM1No-1UBC
PMM2STT3ANo-1UBC
CADDPM1No-2UBC, UBB
CADDPAGT1No-1UBC
CADPGM1No-1UBC
CADSTT3ANo-1UBC
DPM3DPM2Yesbinding1DPM1
DPM3DPM1Yesbinding1DPM2
DPM2DPM1Yesbinding1DPM3
DPM1DPAGT1No-1UBC
DPM1PGM1No-1UBC
DPM1STT3ANo-1UBC
DPAGT1PGM1No-1UBC
DPAGT1STT3ANo-1UBC
DPAGT1ALG13Yesactivation, binding1ALG14
PGM1STT3ANo-1UBC

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Gene1Gene2Direct InteractionComplexesNumber of shared interactorsShared genes in interaction
DDOSTSTT3BYesOligosaccharyltransferase complex (Stt3B variant)5MAGT1, RPN1, TUSC3, DAD1, RPN2
DDOSTSTT3AYesOligosaccharyltransferase complex (Stt3A variant)4MAGT1, RPN1, DAD1, RPN2
STT3BSTT3ANo-5MAGT1, RPN1, DDOST, DAD1, RPN2
DPM3DPM2YesDolichol-phosphate mannose (DPM) synthase1DPM1
DPM3DPM1YesDolichol-phosphate mannose (DPM) synthase1DPM2
DPM2DPM1YesDolichol-phosphate mannose (DPM) synthase1DPM3

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CENSUS
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
DDOSTSTT3BYes1MAGT1
DDOSTSSR4Yes1ILF2
STT3BSSR4No1DDOST

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Metabolic pathwayshsa011002.4921PGM1, MPI, DPM1, DDOST, DPM2, DPM3, ALG11, ALG13, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, PMM2, ALG2
N-Glycan biosynthesishsa005107.0717ALG11, DPM1, DDOST, DPM2, DPM3, ALG13, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG2
Protein processing in endoplasmic reticulumhsa041415.354STT3B, STT3A, DDOST, SSR4
Amino sugar and nucleotide sugar metabolismhsa005207.153MPI, PGM1, PMM2
Fructose and mannose metabolismhsa000517.722MPI, PMM2

NET-GE enrichment

Term New enriched termICP valueGenes
Global and overview mapsNEW2.470.0MPI, DDOST, SSR4, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, ALG6, STT3A, ALG1, PGM1, ALG11, DPM1, ALG13, DPM3
MetabolismNEW2.060.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
Metabolic pathways (hsa01100) -2.490.0MPI, DDOST, SSR4, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, ALG6, STT3A, ALG1, PGM1, ALG11, DPM1, ALG13, DPM3
N-Glycan biosynthesis (hsa00510) -7.070.0ALG11, DPM1, DDOST, DPM2, STT3A, ALG13, DPM3, ALG3, STT3B, ALG1, ALG12, ALG9, ALG8, DOLK, ALG6, DPAGT1, ALG2
Glycan biosynthesis and metabolismNEW4.780.0ALG11, DPM1, DDOST, DPM2, STT3A, ALG13, DPM3, ALG3, STT3B, ALG1, ALG12, ALG9, ALG8, DOLK, ALG6, DPAGT1, ALG2
Amino sugar and nucleotide sugar metabolism (hsa00520) -7.150.013MPI, PGM1, PMM2
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Metabolism of proteinsR-HSA-3924993.4122MPI, DDOST, SSR4, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, ALG6, ALG2, ALG3, STT3A, ALG1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
Post-translational protein modificationR-HSA-5975924.5421MPI, ALG11, DPM1, DDOST, RFT1, MPDU1, DPM3, ALG13, SRD5A3, ALG3, STT3A, ALG1, ALG9, ALG8, DOLK, ALG6, ALG12, DPAGT1, PMM2, ALG2, DPM2
Asparagine N-linked glycosylationR-HSA-4462036.121MPI, ALG11, DPM1, DDOST, RFT1, MPDU1, STT3A, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
Diseases of glycosylationR-HSA-37818656.8920PGM1, MPI, DPM1, DPM3, RFT1, MPDU1, ALG11, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
DiseaseR-HSA-16436853.3320PGM1, MPI, DPM1, DPM3, RFT1, MPDU1, ALG11, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinR-HSA-4461936.9219MPI, ALG11, DPM1, RFT1, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
Diseases associated with N-glycosylation of proteinsR-HSA-37818608.8912ALG11, RFT1, MPDU1, ALG13, ALG9, ALG3, ALG1, ALG12, ALG6, ALG8, DPAGT1, ALG2
Diseases associated with glycosylation precursor biosynthesisR-HSA-56099759.088MPI, DPM1, DPM2, PMM2, SRD5A3, DPM3, DOLK, PGM1
Synthesis of substrates in N-glycan biosythesisR-HSA-4462197.287MPI, DPM1, DPM3, SRD5A3, PMM2, DOLK, DPM2
Post-translational modification: synthesis of GPI-anchored proteinsR-HSA-1631258.283DPM1, DPM2, DPM3
MetabolismR-HSA-14307282.343SRD5A3, CAD, PGM1
Synthesis of dolichyl-phosphate mannoseR-HSA-16269911.43DPM1, DPM2, DPM3
Gene ExpressionR-HSA-741602.722DDOST, SSR4
SRP-dependent cotranslational protein targeting to membraneR-HSA-17993396.242DDOST, SSR4
Synthesis of GDP-mannoseR-HSA-44620510.662MPI, PMM2
Synthesis of Dolichyl-phosphateR-HSA-44619910.662SRD5A3, DOLK
TranslationR-HSA-727665.82DDOST, SSR4

NET-GE enrichment

Term New enriched termICP valueGenes
Post-translational modification: synthesis of GPI-anchored proteins (R-HSA-163125) -8.280.003DPM1, DPM2, DPM3
Synthesis of substrates in N-glycan biosythesis (R-HSA-446219) -7.280.0MPI, DPM1, DPM3, SRD5A3, PMM2, DOLK, DPM2
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (R-HSA-446193) -6.920.0MPI, ALG11, DPM1, RFT1, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
Diseases associated with glycosylation precursor biosynthesis (R-HSA-5609975) -9.080.0MPI, DPM1, DPM2, PMM2, SRD5A3, DPM3, DOLK, PGM1
Post-translational protein modification (R-HSA-597592) -4.540.0MPI, ALG11, DPM1, DDOST, RFT1, MPDU1, DPM3, ALG13, ALG9, ALG3, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, SRD5A3, ALG2
Metabolism of proteins (R-HSA-392499) -3.410.0MPI, DDOST, SSR4, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, ALG6, ALG2, ALG3, SRD5A3, ALG1, ALG11, DPM1, ALG13, STT3A, DPM3, RFT1
Synthesis of Dolichyl-phosphate (R-HSA-446199) -10.660.006SRD5A3, DOLK
Asparagine N-linked glycosylation (R-HSA-446203) -6.10.0ALG11, MPI, DPM1, DDOST, MPDU1, DPM2, STT3A, DPM3, ALG13, ALG9, ALG3, RFT1, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, PMM2, ALG2
Synthesis of GDP-mannose (R-HSA-446205) -10.660.004MPI, PMM2
Diseases of glycosylation (R-HSA-3781865) -6.890.0PGM1, MPI, DPM1, DPM3, RFT1, MPDU1, ALG11, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
Diseases associated with N-glycosylation of proteins (R-HSA-3781860) -8.890.0ALG11, RFT1, MPDU1, ALG13, ALG9, ALG3, ALG1, ALG12, ALG6, ALG8, DPAGT1, ALG2
Synthesis of dolichyl-phosphate mannose (R-HSA-162699) -11.40.0DPM1, DPM2, DPM3
Disease (R-HSA-1643685) -3.330.0PGM1, MPI, DPM1, DDOST, RFT1, MPDU1, DPM3, ALG11, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
catalytic activity (GO:0003824) 1.0522MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
transferase activity (GO:0016740) 1.9518ALG11, DPM1, DDOST, DPM2, DPM3, ALG13, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
transferase activity, transferring glycosyl groups (GO:0016757) 4.0816ALG11, DPM1, DDOST, DPM2, DPM3, ALG13, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, ALG6, DPAGT1, ALG2
transferase activity, transferring hexosyl groups (GO:0016758) 4.4315ALG11, DPM1, DDOST, DPM2, DPM3, ALG13, ALG9, ALG3, STT3B, ALG1, ALG12, ALG6, ALG8, STT3A, ALG2
binding (GO:0005488) 0.1813MPI, DPM1, DDOST, DPM2, MPDU1, ALG13, DPM3, DOLK, STT3A, CAD, ALG2, PMM2, PGM1
protein binding (GO:0005515) 0.4612DPM1, DDOST, DPM2, MPDU1, ALG13, DPM3, PMM2, STT3A, CAD, ALG2, DOLK, PGM1
mannosyltransferase activity (GO:0000030) 6.5210ALG11, DPM1, DPM2, DPM3, ALG9, ALG3, ALG12, ALG1, ALG8, ALG2
cation binding (GO:0043169) 1.43MPI, CAD, PGM1
dolichyl-diphosphooligosaccharide-protein glycotransferase activity (GO:0004579) 7.663STT3B, STT3A, DDOST
isomerase activity (GO:0016853) 4.623MPI, PGM1, PMM2
transferase activity, transferring phosphorus-containing groups (GO:0016772) 2.773DPAGT1, CAD, DOLK
ion binding (GO:0043167) 1.363MPI, CAD, PGM1
oligosaccharyl transferase activity (GO:0004576) 7.543STT3B, STT3A, DDOST
metal ion binding (GO:0046872) 1.413MPI, CAD, PGM1
(GO:0000033) 8.643ALG3, ALG2, ALG8
dolichyl-phosphate beta-D-mannosyltransferase activity (GO:0004582) 8.353DPM1, DPM2, DPM3
hydrolase activity (GO:0016787) 1.92CAD, ALG13
glycolipid mannosyltransferase activity (GO:0004376) 8.352ALG11, ALG2
transition metal ion binding (GO:0046914) 2.482MPI, CAD
phosphotransferase activity, alcohol group as acceptor (GO:0016773) 3.082CAD, DOLK
organic cyclic compound binding (GO:0097159) 1.052CAD, ALG13
kinase activity (GO:0016301) 2.932CAD, DOLK
(GO:0042281) 9.052ALG6, ALG8
glucosyltransferase activity (GO:0046527) 6.972ALG6, ALG8
small molecule binding (GO:0036094) 1.892DPM1, CAD
zinc ion binding (GO:0008270) 2.662MPI, CAD
intramolecular transferase activity, phosphotransferases (GO:0016868) 7.342PGM1, PMM2
intramolecular transferase activity (GO:0016866) 6.442PGM1, PMM2
(GO:0004583) 8.352ALG6, ALG8
heterocyclic compound binding (GO:1901363) 1.062CAD, ALG13
(GO:0000026) 8.642ALG11, ALG9

NET-GE enrichment

Term New enriched termICP valueGenes
glycolipid mannosyltransferase activity (GO:0004376) -8.350.0ALG11, ALG2
alpha-1,6-mannosyltransferase activity (GO:0000009) NEW9.740.0ALG12, ALG2
catalytic activity (GO:0003824) -1.050.0PGM1, MPI, DPM1, STT3A, ALG11, ALG13, ALG9, ALG3, STT3B, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, PMM2, ALG2
transferase activity (GO:0016740) -1.950.0ALG11, DPM1, DDOST, DPM2, ALG13, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
oligosaccharyl transferase activity (GO:0004576) -7.540.0STT3B, STT3A, DDOST
transferase activity, transferring glycosyl groups (GO:0016757) -4.080.0ALG11, DPM1, DDOST, DPM2, ALG13, ALG9, ALG3, ALG6, STT3A, ALG12, ALG1, ALG8, STT3B, DPAGT1, ALG2
intramolecular transferase activity, phosphotransferases (GO:0016868) -7.340.014PGM1, PMM2
transferase activity, transferring hexosyl groups (GO:0016758) -4.430.0ALG11, DPM1, DPM2, ALG13, ALG9, ALG3, STT3B, ALG1, ALG12, ALG6, ALG8, STT3A, ALG2
dolichyl-diphosphooligosaccharide-protein glycotransferase activity (GO:0004579) -7.660.003STT3B, STT3A
alpha-1,3-mannosyltransferase activity (GO:0000033) -8.640.0ALG3, ALG2, ALG8
alpha-1,2-mannosyltransferase activity (GO:0000026) -8.640.001ALG11, ALG9
mannosyltransferase activity (GO:0000030) -6.520.0ALG11, DPM1, ALG9, ALG3, ALG12, ALG1, ALG8, ALG2
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
single-organism process (GO:0044699) 0.4824MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
primary metabolic process (GO:0044238) 0.6923MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
single-organism metabolic process (GO:0044710) 1.6323MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
cellular process (GO:0009987) 0.2623MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, DPM1, ALG13, SRD5A3, DPM3, RFT1
organic substance metabolic process (GO:0071704) 0.6323MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
single-organism cellular process (GO:0044763) 0.6523MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, DPM1, ALG13, SRD5A3, DPM3, RFT1
metabolic process (GO:0008152) 0.5823MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
cellular metabolic process (GO:0044237) 0.6922MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, DPM1, ALG13, SRD5A3, DPM3
single-organism carbohydrate metabolic process (GO:0044723) 3.4220PGM1, MPI, DPM1, DDOST, DPM2, MPDU1, DPM3, ALG11, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, ALG6, DPAGT1, PMM2, SRD5A3, ALG2
carbohydrate metabolic process (GO:0005975) 3.2620PGM1, MPI, DPM1, DDOST, DPM2, MPDU1, DPM3, ALG11, ALG9, ALG3, STT3B, ALG1, ALG12, ALG6, ALG8, STT3A, DPAGT1, PMM2, SRD5A3, ALG2
organic substance biosynthetic process (GO:1901576) 1.3419PGM1, MPI, DPM1, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, PMM2, ALG2
carbohydrate derivative metabolic process (GO:1901135) 3.0719PGM1, MPI, DPM1, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, ALG1, ALG12, ALG6, ALG8, STT3B, CAD, DPAGT1, PMM2, SRD5A3, ALG2
biosynthetic process (GO:0009058) 1.3219PGM1, MPI, DPM1, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, PMM2, ALG2
macromolecule metabolic process (GO:0043170) 0.8319PGM1, DPM1, DDOST, DPM2, DPM3, ALG13, ALG9, ALG3, STT3B, ALG1, ALG12, ALG6, ALG8, STT3A, CAD, DPAGT1, PMM2, SRD5A3, ALG2
protein metabolic process (GO:0019538) 1.4518SRD5A3, DPM1, DDOST, DPM2, STT3A, DPM3, ALG13, ALG9, ALG3, ALG1, ALG12, ALG6, ALG8, STT3B, CAD, DPAGT1, PMM2, ALG2
cellular macromolecule metabolic process (GO:0044260) 0.9318PGM1, DPM1, DDOST, DPM2, DPM3, ALG9, ALG6, ALG3, STT3A, ALG12, ALG1, ALG8, STT3B, CAD, DPAGT1, PMM2, SRD5A3, ALG2
cellular protein metabolic process (GO:0044267) 1.6317DPM1, DDOST, DPM2, STT3A, DPM3, ALG9, ALG3, STT3B, SRD5A3, ALG12, ALG1, ALG8, ALG6, CAD, DPAGT1, PMM2, ALG2
single-organism biosynthetic process (GO:0044711) 2.817PGM1, DPM1, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
carbohydrate derivative biosynthetic process (GO:1901137) 3.7317MPI, DPM1, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, ALG1, ALG12, ALG6, ALG8, CAD, DPAGT1, PMM2, SRD5A3, ALG2
glycosylation (GO:0070085) 4.1617ALG11, DPM1, DDOST, DPM2, STT3A, DPM3, ALG9, ALG3, STT3B, SRD5A3, ALG12, ALG1, ALG8, ALG6, DPAGT1, PMM2, ALG2
cellular protein modification process (GO:0006464) 1.7917SRD5A3, DPM1, DDOST, DPM2, DPM3, ALG9, ALG3, STT3B, ALG1, ALG12, ALG6, ALG8, STT3A, CAD, DPAGT1, PMM2, ALG2
macromolecule modification (GO:0043412) 1.7317SRD5A3, DPM1, DDOST, DPM2, DPM3, ALG9, ALG3, STT3B, ALG1, ALG12, ALG6, ALG8, STT3A, CAD, DPAGT1, PMM2, ALG2
protein modification process (GO:0036211) 1.7917DPM1, DDOST, DPM2, STT3A, DPM3, ALG9, ALG3, STT3B, SRD5A3, ALG12, ALG1, ALG8, ALG6, CAD, DPAGT1, PMM2, ALG2
macromolecule glycosylation (GO:0043413) 4.216SRD5A3, DPM1, DDOST, DPM2, DPM3, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, ALG6, DPAGT1, PMM2, ALG2
protein glycosylation (GO:0006486) 4.216SRD5A3, DPM1, DDOST, DPM2, DPM3, ALG9, ALG3, STT3A, ALG1, ALG6, ALG8, STT3B, ALG12, DPAGT1, PMM2, ALG2
cellular lipid metabolic process (GO:0044255) 2.9215DPM1, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG2
lipid metabolic process (GO:0006629) 2.6815DPM1, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG2
dolichol-linked oligosaccharide biosynthetic process (GO:0006488) 7.0211SRD5A3, MPDU1, ALG13, ALG9, ALG3, ALG1, ALG12, ALG6, ALG8, DPAGT1, ALG2
cellular biosynthetic process (GO:0044249) 1.3711MPI, DPM1, DPM2, DPM3, ALG1, SRD5A3, CAD, DOLK, DPAGT1, PMM2, PGM1
oligosaccharide-lipid intermediate biosynthetic process (GO:0006490) 7.0211SRD5A3, MPDU1, ALG13, ALG9, ALG3, ALG1, ALG12, ALG6, ALG8, DPAGT1, ALG2
mannosylation (GO:0097502) 6.2610ALG11, DPM1, DPM2, DPM3, ALG9, ALG3, ALG12, ALG1, ALG8, ALG2
protein N-linked glycosylation (GO:0006487) 5.6510DPM1, DDOST, ALG6, STT3A, ALG12, DPM3, ALG8, STT3B, DPAGT1, DPM2
organophosphate metabolic process (GO:0019637) 3.048MPI, DPM1, DPM3, SRD5A3, CAD, PGM1, DOLK, DPM2
phosphate-containing compound metabolic process (GO:0006796) 2.168MPI, DPM1, DPM3, SRD5A3, CAD, PGM1, DOLK, DPM2
phosphorus metabolic process (GO:0006793) 2.158MPI, DPM1, DPM3, SRD5A3, CAD, PGM1, DOLK, DPM2
small molecule metabolic process (GO:0044281) 2.387MPI, DPM1, SRD5A3, CAD, PGM1, DPAGT1, DPM2
peptidyl-amino acid modification (GO:0018193) 2.987DPM1, DDOST, DPM3, STT3A, CAD, STT3B, DPM2
lipid biosynthetic process (GO:0008610) 3.497DPM1, DPM3, SRD5A3, ALG1, DOLK, DPAGT1, DPM2
nucleobase-containing compound metabolic process (GO:0006139) 1.356MPI, DPM1, PMM2, CAD, DPAGT1, PGM1
peptidyl-asparagine modification (GO:0018196) 6.076DPM1, DDOST, DPM3, STT3A, STT3B, DPM2
cellular aromatic compound metabolic process (GO:0006725) 1.36MPI, DPM1, PMM2, CAD, DPAGT1, PGM1
cellular nitrogen compound metabolic process (GO:0034641) 1.226MPI, DPM1, PMM2, CAD, DPAGT1, PGM1
nitrogen compound metabolic process (GO:0006807) 1.136MPI, DPM1, PMM2, CAD, DPAGT1, PGM1
organophosphate biosynthetic process (GO:0090407) 3.676DPM1, DPM3, SRD5A3, CAD, DOLK, DPM2
protein N-linked glycosylation via asparagine (GO:0018279) 6.096DPM1, DDOST, DPM3, STT3A, STT3B, DPM2
organic cyclic compound metabolic process (GO:1901360) 1.266MPI, DPM1, PMM2, CAD, DPAGT1, PGM1
heterocycle metabolic process (GO:0046483) 1.316MPI, DPM1, PMM2, CAD, DPAGT1, PGM1
phospholipid metabolic process (GO:0006644) 3.885DPM2, SRD5A3, DPM1, DPM3, DOLK
regulation of biological quality (GO:0065008) 1.685DPM2, SRD5A3, CAD, DPM3, RFT1
biological regulation (GO:0065007) 0.395DPM2, SRD5A3, CAD, DPM3, RFT1
phospholipid biosynthetic process (GO:0008654) 4.395DPM2, SRD5A3, DPM1, DPM3, DOLK
liposaccharide metabolic process (GO:1903509) 4.984DPM2, DPM1, DPM3, ALG1
nucleotide-sugar metabolic process (GO:0009225) 6.234MPI, DPAGT1, DPM1, PMM2
polyprenol metabolic process (GO:0016093) 7.654DPM1, SRD5A3, DPAGT1, DPM2
response to stimulus (GO:0050896) 1.224STT3B, CAD, DDOST, ALG2
alcohol metabolic process (GO:0006066) 4.24DPM1, SRD5A3, DPAGT1, DPM2
isoprenoid metabolic process (GO:0006720) 4.894DPM1, SRD5A3, DPAGT1, DPM2
response to chemical (GO:0042221) 1.984STT3B, CAD, DDOST, ALG2
dolichol metabolic process (GO:0019348) 7.944DPM1, SRD5A3, DPAGT1, DPM2
organic hydroxy compound metabolic process (GO:1901615) 3.844DPM1, SRD5A3, DPAGT1, DPM2
GDP-mannose metabolic process (GO:0019673) 7.653MPI, DPM1, PMM2
glycerophospholipid metabolic process (GO:0006650) 4.133DPM1, DPM2, DPM3
phosphorylation (GO:0016310) 2.633CAD, PGM1, DOLK
cellular catabolic process (GO:0044248) 2.623STT3B, SRD5A3, PGM1
small molecule biosynthetic process (GO:0044283) 3.793DPAGT1, CAD, PGM1
protein mannosylation (GO:0035268) 6.733DPM1, DPM2, DPM3
protein O-linked mannosylation (GO:0035269) 7.093DPM1, DPM2, DPM3
organic cyclic compound biosynthetic process (GO:1901362) 1.663MPI, CAD, PMM2
glycerolipid biosynthetic process (GO:0045017) 4.533DPM1, DPM2, DPM3
organic substance catabolic process (GO:1901575) 2.453STT3B, SRD5A3, PGM1
localization (GO:0051179) 1.43CAD, MPDU1, RFT1
GPI anchor metabolic process (GO:0006505) 6.233DPM1, DPM2, DPM3
GPI anchor biosynthetic process (GO:0006506) 6.263DPM1, DPM2, DPM3
phosphatidylinositol biosynthetic process (GO:0006661) 4.943DPM1, DPM2, DPM3
glycolipid metabolic process (GO:0006664) 5.013DPM1, DPM2, DPM3
heterocycle biosynthetic process (GO:0018130) 1.73MPI, CAD, PMM2
membrane lipid metabolic process (GO:0006643) 4.513DPM1, DPM2, DPM3
transport (GO:0006810) 1.513CAD, MPDU1, RFT1
glycolipid biosynthetic process (GO:0009247) 5.63DPM1, DPM2, DPM3
phosphatidylinositol metabolic process (GO:0046488) 4.463DPM1, DPM2, DPM3
aromatic compound biosynthetic process (GO:0019438) 1.73MPI, CAD, PMM2
nucleobase-containing compound biosynthetic process (GO:0034654) 1.723MPI, CAD, PMM2
cellular nitrogen compound biosynthetic process (GO:0044271) 1.593MPI, CAD, PMM2
glycerolipid metabolic process (GO:0046486) 3.913DPM1, DPM2, DPM3
establishment of localization (GO:0051234) 1.483CAD, MPDU1, RFT1
catabolic process (GO:0009056) 2.383STT3B, SRD5A3, PGM1
response to organic substance (GO:0010033) 2.23STT3B, CAD, DDOST
protein lipidation (GO:0006497) 5.383DPM1, DPM2, DPM3
protein O-linked glycosylation (GO:0006493) 5.133DPM1, DPM2, DPM3
membrane lipid biosynthetic process (GO:0046467) 4.993DPM1, DPM2, DPM3
carbohydrate biosynthetic process (GO:0016051) 4.933MPDU1, PGM1, ALG1
glycerophospholipid biosynthetic process (GO:0046474) 4.623DPM1, DPM2, DPM3
protein folding (GO:0006457) 4.322MPDU1, ALG12
cellular macromolecule biosynthetic process (GO:0034645) 1.662PGM1, ALG1
nucleoside triphosphate metabolic process (GO:0009141) 4.612CAD, PGM1
carboxylic acid metabolic process (GO:0019752) 3.122CAD, PGM1
GDP-mannose biosynthetic process (GO:0009298) 8.342MPI, PMM2
small molecule catabolic process (GO:0044282) 3.992SRD5A3, PGM1
ribonucleoside monophosphate metabolic process (GO:0009161) 4.622CAD, PGM1
nucleoside monophosphate metabolic process (GO:0009123) 4.542CAD, PGM1
ribonucleotide metabolic process (GO:0009259) 4.112CAD, PGM1
cellular component organization or biogenesis (GO:0071840) 1.222DPAGT1, RFT1
single-organism catabolic process (GO:0044712) 3.212SRD5A3, PGM1
cellular polysaccharide metabolic process (GO:0044264) 5.412PGM1, ALG1
cellular carbohydrate metabolic process (GO:0044262) 4.742PGM1, ALG1
dolichyl diphosphate biosynthetic process (GO:0006489) 7.942SRD5A3, DOLK
cellular component organization (GO:0016043) 1.242DPAGT1, RFT1
ribonucleoside triphosphate metabolic process (GO:0009199) 4.772CAD, PGM1
single-organism localization (GO:1902578) 2.092CAD, RFT1
proteolysis (GO:0006508) 2.732STT3B, ALG13
dolichyl diphosphate metabolic process (GO:0046465) 7.942SRD5A3, DOLK
co-translational protein modification (GO:0043686) 9.042STT3B, STT3A
hexose metabolic process (GO:0019318) 4.642MPI, PGM1
post-translational protein modification (GO:0043687) 6.172STT3B, STT3A
nucleotide-sugar biosynthetic process (GO:0009226) 6.782MPI, PMM2
polysaccharide biosynthetic process (GO:0000271) 5.942PGM1, ALG1
nucleobase-containing small molecule metabolic process (GO:0055086) 3.592CAD, PGM1
cellular carbohydrate biosynthetic process (GO:0034637) 5.762PGM1, ALG1
single-organism transport (GO:0044765) 2.182CAD, RFT1
macromolecule biosynthetic process (GO:0009059) 1.612PGM1, ALG1
nucleotide metabolic process (GO:0009117) 3.732CAD, PGM1
nucleoside metabolic process (GO:0009116) 4.122CAD, PGM1
oxoacid metabolic process (GO:0043436) 3.122CAD, PGM1
ribonucleoside metabolic process (GO:0009119) 4.212CAD, PGM1
macromolecule catabolic process (GO:0009057) 3.02STT3B, PGM1
oxidation-reduction process (GO:0055114) 2.912SRD5A3, PGM1
organonitrogen compound metabolic process (GO:1901564) 2.322CAD, PGM1
organic acid metabolic process (GO:0006082) 3.012CAD, PGM1
polysaccharide metabolic process (GO:0005976) 5.322PGM1, ALG1
monosaccharide metabolic process (GO:0005996) 4.572MPI, PGM1
regulation of protein stability (GO:0031647) 4.332DPM2, DPM3
ribose phosphate metabolic process (GO:0019693) 4.062CAD, PGM1
cellular polysaccharide biosynthetic process (GO:0033692) 6.022PGM1, ALG1
glycosyl compound metabolic process (GO:1901657) 4.042CAD, PGM1
nucleoside phosphate metabolic process (GO:0006753) 3.712CAD, PGM1

NET-GE enrichment

Term New enriched termICP valueGenes
GDP-mannose metabolic process (GO:0019673) -7.650.0MPI, DPM1, PMM2
C-terminal protein amino acid modification (GO:0018410) NEW7.090.004DPM1, DPM2, DPM3
polyprenol metabolic process (GO:0016093) -7.650.0DPM1, SRD5A3, DPAGT1, DPM2
GDP-mannose biosynthetic process (GO:0009298) -8.340.009MPI, PMM2
protein mannosylation (GO:0035268) -6.730.0DPM1, DPM2, DPM3
protein O-linked mannosylation (GO:0035269) -7.090.0DPM1, DPM2, DPM3
single-organism process (GO:0044699) -0.480.004MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
organic substance biosynthetic process (GO:1901576) -1.340.0MPI, DDOST, SSR4, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, ALG6, ALG2, ALG3, SRD5A3, ALG1, PGM1, ALG11, DPM1, ALG13, DPM3, RFT1
single-organism metabolic process (GO:0044710) -1.630.0MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
single-organism biosynthetic process (GO:0044711) -2.80.0MPI, DPM1, DPM2, MPDU1, DPM3, ALG1, SRD5A3, CAD, DOLK, DPAGT1, PMM2, PGM1
cellular macromolecule metabolic process (GO:0044260) -0.930.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
protein N-linked glycosylation (GO:0006487) -5.650.0MPI, ALG11, DPM1, DDOST, RFT1, DPM2, DPM3, ALG13, SRD5A3, ALG3, ALG6, STT3A, ALG1, ALG9, ALG8, DOLK, STT3B, ALG12, DPAGT1, PMM2, ALG2
dolichol-linked oligosaccharide biosynthetic process (GO:0006488) -7.020.0MPI, ALG11, DPM1, RFT1, MPDU1, DPM3, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPM2, DPAGT1, PMM2, ALG2
dolichyl diphosphate biosynthetic process (GO:0006489) -7.940.026SRD5A3, DOLK
peptidyl-asparagine modification (GO:0018196) -6.070.0MPI, ALG11, DPM1, DDOST, RFT1, DPM2, STT3A, DPM3, ALG13, ALG9, ALG3, ALG6, ALG1, ALG12, DOLK, ALG8, STT3B, DPAGT1, PMM2, SRD5A3, ALG2
peptidyl-amino acid modification (GO:0018193) -2.980.0MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
C-terminal protein lipidation (GO:0006501) NEW7.780.011DPM1, DPM2, DPM3
organic substance metabolic process (GO:0071704) -0.630.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
GPI anchor metabolic process (GO:0006505) -6.230.011DPM1, DPM2, DPM3
isoprenoid metabolic process (GO:0006720) -4.890.006DPM1, SRD5A3, DPAGT1, DPM2
phosphatidylinositol biosynthetic process (GO:0006661) -4.940.001DPM2, DPM1, DDOST, DPM3, SSR4
dolichyl diphosphate metabolic process (GO:0046465) -7.940.026SRD5A3, DOLK
protein N-linked glycosylation via asparagine (GO:0018279) -6.090.0MPI, ALG11, DPM1, DDOST, RFT1, DPM2, DPM3, ALG13, SRD5A3, ALG3, ALG6, STT3A, ALG1, ALG9, ALG8, DOLK, STT3B, ALG12, DPAGT1, PMM2, ALG2
phospholipid metabolic process (GO:0006644) -3.880.031DPM1, DDOST, DPM3, SSR4, SRD5A3, DOLK, DPM2
lipid metabolic process (GO:0006629) -2.680.029DPM1, ALG13, DPM3, ALG1, SRD5A3, DOLK, DPAGT1, DPM2
cellular protein metabolic process (GO:0044267) -1.630.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
nucleotide-sugar metabolic process (GO:0009225) -6.230.0MPI, DPAGT1, DPM1, PMM2
glycolipid biosynthetic process (GO:0009247) -5.60.012DPM1, DPM2, DPM3
post-translational protein modification (GO:0043687) -6.170.0MPI, ALG11, DPM1, DDOST, RFT1, DPM2, DPM3, ALG13, SRD5A3, ALG3, STT3B, STT3A, ALG1, ALG9, ALG8, DOLK, ALG6, ALG12, DPAGT1, PMM2, ALG2
co-translational protein modification (GO:0043686) -9.040.001STT3B, STT3A
glycosylation (GO:0070085) -4.160.0MPI, ALG11, DPM1, DDOST, RFT1, DPM2, STT3A, DPM3, ALG13, ALG9, ALG3, ALG6, ALG1, ALG12, ALG8, DOLK, STT3B, DPAGT1, PMM2, SRD5A3, ALG2
cellular protein modification process (GO:0006464) -1.790.0MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
biosynthetic process (GO:0009058) -1.320.0MPI, DDOST, SSR4, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, ALG6, ALG2, ALG3, SRD5A3, ALG1, PGM1, ALG11, DPM1, ALG13, DPM3, RFT1
macromolecule modification (GO:0043412) -1.730.0MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
macromolecule glycosylation (GO:0043413) -4.20.0MPI, ALG11, DPM1, DDOST, RFT1, DPM2, DPM3, ALG13, SRD5A3, ALG3, STT3B, STT3A, ALG1, ALG9, ALG8, DOLK, ALG6, ALG12, DPAGT1, PMM2, ALG2
phosphatidylinositol metabolic process (GO:0046488) -4.460.019DPM2, DPM1, DDOST, DPM3, SSR4
metabolic process (GO:0008152) -0.580.001MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
single-organism carbohydrate metabolic process (GO:0044723) -3.420.0MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
cellular lipid metabolic process (GO:0044255) -2.920.018DPM1, DDOST, DPM2, ALG13, DPM3, SSR4, SRD5A3, CAD, ALG1, DOLK, DPAGT1, PGM1
organophosphate biosynthetic process (GO:0090407) -3.670.001MPI, DPM1, DDOST, DPM3, PMM2, SRD5A3, CAD, SSR4, DOLK, DPM2
carbohydrate biosynthetic process (GO:0016051) -4.930.01PGM1, MPDU1, ALG1, PMM2
lipid biosynthetic process (GO:0008610) -3.490.029DPM1, DDOST, DPM3, SSR4, SRD5A3, ALG1, DOLK, DPAGT1, DPM2
protein lipidation (GO:0006497) -5.380.021DPM1, DDOST, DPM2, DPM3
primary metabolic process (GO:0044238) -0.690.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
carbohydrate metabolic process (GO:0005975) -3.260.0MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
protein glycosylation (GO:0006486) -4.20.0MPI, ALG11, DPM1, DDOST, RFT1, DPM2, DPM3, ALG13, SRD5A3, ALG3, ALG6, STT3A, ALG1, ALG9, ALG8, DOLK, STT3B, ALG12, DPAGT1, PMM2, ALG2
phospholipid biosynthetic process (GO:0008654) -4.390.001DPM1, DDOST, DPM3, SSR4, SRD5A3, DOLK, DPM2
protein metabolic process (GO:0019538) -1.450.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
carbohydrate derivative metabolic process (GO:1901135) -3.070.0MPI, ALG11, DPM1, MPDU1, DPM2, DPM3, ALG13, ALG9, ALG3, RFT1, STT3B, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, PMM2, ALG2
mannosylation (GO:0097502) -6.260.0ALG11, DPM1, DPM2, DPM3, ALG9, ALG3, ALG12, ALG1, ALG8, ALG2
cellular metabolic process (GO:0044237) -0.690.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
macromolecule metabolic process (GO:0043170) -0.830.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
carbohydrate derivative biosynthetic process (GO:1901137) -3.730.0MPI, DDOST, SSR4, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, ALG6, ALG2, ALG3, SRD5A3, ALG1, ALG11, DPM1, ALG13, DPM3, RFT1
protein modification process (GO:0036211) -1.790.0MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
organophosphate metabolic process (GO:0019637) -3.040.015MPI, DPM1, DPM3, SRD5A3, CAD, PMM2, DOLK, DPAGT1, DPM2
single-organism cellular process (GO:0044763) -0.650.007MPI, DDOST, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
GPI anchor biosynthetic process (GO:0006506) -6.260.003DPM1, DPM2, DPM3
dolichol metabolic process (GO:0019348) -7.940.0DPM1, SRD5A3, DPAGT1, DPM2
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
intracellular part (GO:0044424) 0.2825MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
cytoplasmic part (GO:0044444) 0.8225MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
cell part (GO:0044464) 0.1125MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
membrane-bounded organelle (GO:0043227) 0.4724MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, SRD5A3, ALG6, PGM1, ALG11, DPM1, ALG13, STT3A, DPM3
organelle (GO:0043226) 0.424MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, SRD5A3, ALG6, PGM1, ALG11, DPM1, ALG13, STT3A, DPM3
intracellular organelle part (GO:0044446) 0.8122DDOST, SSR4, CAD, ALG9, DPAGT1, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, ALG6, STT3A, ALG1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
intracellular organelle (GO:0043229) 0.5122DDOST, SSR4, CAD, ALG9, DPAGT1, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, ALG6, STT3A, ALG1, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
membrane (GO:0016020) 0.6822DDOST, SSR4, CAD, ALG9, DPAGT1, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, ALG6, STT3A, ALG1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
organelle part (GO:0044422) 0.7922DDOST, SSR4, CAD, ALG9, DPAGT1, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, ALG6, STT3A, ALG1, ALG11, DPM1, ALG13, SRD5A3, DPM3, RFT1
membrane part (GO:0044425) 0.9521ALG11, DPM1, DDOST, MPDU1, DPM2, STT3A, DPM3, SSR4, ALG13, ALG9, ALG3, RFT1, ALG6, ALG1, ALG12, DOLK, ALG8, STT3B, DPAGT1, SRD5A3, ALG2
endoplasmic reticulum part (GO:0044432) 2.7321SRD5A3, ALG11, DPM1, DDOST, RFT1, MPDU1, STT3A, DPM3, SSR4, ALG13, ALG9, ALG3, STT3B, ALG1, ALG12, DOLK, ALG8, ALG6, DPM2, DPAGT1, ALG2
intracellular membrane-bounded organelle (GO:0043231) 0.621ALG11, DPM1, DDOST, DPM2, MPDU1, STT3A, DPM3, SSR4, ALG13, SRD5A3, ALG3, STT3B, ALG1, ALG12, ALG9, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
endoplasmic reticulum membrane (GO:0005789) 2.9521ALG11, DPM1, DDOST, RFT1, MPDU1, DPM3, SSR4, ALG13, STT3A, ALG3, STT3B, ALG1, ALG12, ALG9, ALG8, DOLK, ALG6, DPM2, DPAGT1, SRD5A3, ALG2
integral component of membrane (GO:0016021) 1.1419ALG11, DDOST, MPDU1, DPM2, STT3A, DPM3, SSR4, ALG9, ALG3, RFT1, STT3B, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG2
endoplasmic reticulum (GO:0005783) 2.5619SRD5A3, ALG11, DPM1, DDOST, DPM2, MPDU1, DPM3, SSR4, ALG13, ALG9, ALG3, STT3B, STT3A, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG12
intrinsic component of membrane (GO:0031224) 1.1319ALG11, DDOST, RFT1, MPDU1, STT3A, DPM3, SSR4, SRD5A3, ALG3, STT3B, ALG1, ALG12, ALG9, ALG8, DOLK, ALG6, DPM2, DPAGT1, ALG2
protein complex (GO:0043234) 1.518DPM1, DDOST, DPM3, STT3A, CAD, SSR4, STT3B, DPM2
macromolecular complex (GO:0032991) 1.358DPM1, DDOST, DPM3, STT3A, CAD, SSR4, STT3B, DPM2
cytoplasm (GO:0005737) 1.016MPI, PMM2, SRD5A3, CAD, ALG2, PGM1
extracellular organelle (GO:0043230) 1.896MPI, MPDU1, PMM2, CAD, SSR4, PGM1
vesicle (GO:0031982) 1.646MPI, MPDU1, PMM2, CAD, SSR4, PGM1
extracellular exosome (GO:0070062) 1.896MPI, MPDU1, PMM2, CAD, SSR4, PGM1
membrane-bounded vesicle (GO:0031988) 1.716MPI, MPDU1, PMM2, CAD, SSR4, PGM1
transferase complex (GO:1990234) 3.326DPM1, DDOST, DPM3, STT3A, STT3B, DPM2
extracellular vesicle (GO:1903561) 1.896MPI, MPDU1, PMM2, CAD, SSR4, PGM1
extracellular region part (GO:0044421) 1.576MPI, MPDU1, PMM2, CAD, SSR4, PGM1
catalytic complex (GO:1902494) 2.96DPM1, DDOST, DPM3, STT3A, STT3B, DPM2
membrane protein complex (GO:0098796) 2.844STT3B, STT3A, DDOST, SSR4
cytosol (GO:0005829) 1.684MPI, CAD, PGM1, PMM2
integral component of endoplasmic reticulum membrane (GO:0030176) 5.014DPM2, DPAGT1, DPM3, DOLK
intrinsic component of endoplasmic reticulum membrane (GO:0031227) 4.974DPM2, DPAGT1, DPM3, DOLK
mannosyltransferase complex (GO:0031501) 7.723DPM1, DPM2, DPM3
dolichol-phosphate-mannose synthase complex (GO:0033185) 8.73DPM1, DPM2, DPM3
nucleus (GO:0005634) 1.073DPM1, CAD, ALG2
oligosaccharyltransferase complex (GO:0008250) 7.53STT3B, STT3A, DDOST
cell body (GO:0044297) 3.742CAD, PMM2
neuron part (GO:0097458) 2.642CAD, PMM2
neuronal cell body (GO:0043025) 3.92CAD, PMM2

NET-GE enrichment

Term New enriched termICP valueGenes
mannosyltransferase complex (GO:0031501) -7.720.0DPM1, DPM2, DPM3
membrane region (GO:0098589) NEW3.950.0PGM1, ALG11, DPM1, DDOST, DPM2, MPDU1, STT3A, DPM3, SSR4, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
organelle membrane (GO:0031090) NEW1.970.0ALG11, DPM1, DDOST, DPM2, MPDU1, STT3A, DPM3, SSR4, ALG13, ALG9, ALG3, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
bounding membrane of organelle (GO:0098588) NEW2.390.0SRD5A3, ALG11, DPM1, DDOST, DPM2, MPDU1, DPM3, ALG13, ALG9, ALG3, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG2
membrane (GO:0016020) -0.680.001ALG11, DPM1, DDOST, DPM2, MPDU1, STT3A, ALG13, ALG9, ALG3, STT3B, ALG1, ALG12, DPM3, ALG8, DOLK, ALG6, CAD, DPAGT1, SRD5A3, ALG2
endoplasmic reticulum membrane (GO:0005789) -2.950.0SRD5A3, ALG11, DPM1, DDOST, DPM2, MPDU1, DPM3, SSR4, ALG13, ALG9, ALG3, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG2
intracellular organelle part (GO:0044446) -0.810.0ALG11, DPM1, DDOST, MPDU1, DPM2, STT3A, DPM3, SSR4, ALG13, SRD5A3, ALG3, STT3B, ALG1, ALG12, ALG9, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
endoplasmic reticulum part (GO:0044432) -2.730.0ALG11, DPM1, DDOST, DPM2, MPDU1, DPM3, SSR4, ALG13, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, SRD5A3, ALG2
cytoplasmic part (GO:0044444) -0.820.0MPI, DDOST, SSR4, ALG1, CAD, ALG9, DPAGT1, PMM2, DPM2, MPDU1, DOLK, ALG12, ALG8, STT3B, ALG2, ALG3, STT3A, ALG6, PGM1, ALG11, DPM1, ALG13, SRD5A3, DPM3
integral component of endoplasmic reticulum membrane (GO:0030176) -5.010.0DPM1, DPM3, SSR4, DOLK, DPAGT1, DPM2
integral component of organelle membrane (GO:0031301) NEW4.850.025DPM1, DPM3, SSR4, DOLK, DPAGT1, DPM2
transferase complex (GO:1990234) -3.320.002DPM1, DDOST, DPM3, STT3A, STT3B, DPM2
endoplasmic reticulum (GO:0005783) -2.560.0DPM1, DDOST, DPM2, MPDU1, DPM3, SSR4, ALG3, SRD5A3, ALG12, ALG1, CAD, PGM1
membrane part (GO:0044425) -0.950.0ALG11, DPM1, DDOST, MPDU1, DPM2, STT3A, DPM3, SSR4, ALG13, ALG9, ALG3, RFT1, ALG6, ALG1, ALG12, DOLK, ALG8, STT3B, DPAGT1, SRD5A3, ALG2
dolichol-phosphate-mannose synthase complex (GO:0033185) -8.70.0DPM1, DPM2, DPM3
oligosaccharyltransferase complex (GO:0008250) -7.50.0STT3B, STT3A, DDOST
integral component of membrane (GO:0016021) -1.140.0ALG11, DDOST, MPDU1, DPM2, STT3A, DPM3, SSR4, ALG9, ALG3, RFT1, STT3B, SRD5A3, ALG12, ALG1, ALG8, DOLK, ALG6, DPAGT1, ALG2
organelle part (GO:0044422) -0.790.0SRD5A3, ALG11, DPM1, DDOST, DPM2, MPDU1, DPM3, SSR4, ALG13, ALG9, ALG3, STT3B, STT3A, ALG12, ALG1, ALG8, DOLK, ALG6, CAD, DPAGT1, ALG2
catalytic complex (GO:1902494) -2.90.022DPM1, DDOST, DPM3, STT3A, STT3B, DPM2